A5048314505- Nanofabrication and Lithography Techniques
- Molecular Junctions and Nanostructures
- Bacterial biofilms and quorum sensing
- Electrodeposition and Electroless Coatings
- Electrochemical Analysis and Applications
- Bone Tissue Engineering Materials
- Force Microscopy Techniques and Applications
- Theoretical and Computational Physics
- Graphene and Nanomaterials Applications
- Photodynamic Therapy Research Studies
- Polymer Surface Interaction Studies
- Antimicrobial agents and applications
- Nanoparticles: synthesis and applications
- Biosensors and Analytical Detection
- Nanoplatforms for cancer theranostics
- Corrosion Behavior and Inhibition
- Advanced biosensing and bioanalysis techniques
- Ion-surface interactions and analysis
- Gold and Silver Nanoparticles Synthesis and Applications
- Material Dynamics and Properties
- Antimicrobial Peptides and Activities
- Nanotechnology research and applications
- Science, Technology, and Education in Latin America
- Copper Interconnects and Reliability
- Electrocatalysts for Energy Conversion
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas
2013-2024
Consejo Nacional de Investigaciones Científicas y Técnicas
2013-2024
Universidad Nacional de La Plata
2011-2024
Centro Científico Tecnológico - Tucumán
2009
Universidad de La Laguna
2005
Bangladesh University of Engineering and Technology
2001
A common problem with implants is that bacteria can form biofilms on their surfaces, which lead to infection and, eventually, implant rejection. An interesting strategy inhibit bacterial colonization the immobilization of silver (Ag) species surface devices. The aim this paper investigate action citrate-capped nanoparticles (AgNPs) clinically relevant Gram-positive (Staphylococcus aureus) and Gram-negative (Pseudomonas aeruginosa) in two different situations: (i) dispersed AgNPs (to assess...
The adhesion of Pseudomonas fluorescens was studied on nano/microengineered surfaces. Results show that these bacteria formed well-defined aggregates randomly oriented nanosized granular gold substrates. These consist aligned ensembles bacteria, with some them strongly elongated. This kind biological structure not found ordered engineered surfaces because bacterial alignment and cell-to-cell sticking were hindered. Importantly, differences in cell morphology, length, orientation,...
Device-associated infections (DAI) remain a serious concern in modern healthcare. Bacterial attachment to surface is the first step biofilm formation, which one of main causes DAIs. The development materials capable preventing or inhibiting bacterial constitutes promising approach deal with this problem. multifactorial nature maturation and antibiotic resistance directs research for multitargeted combinatorial therapeutic approaches. One attractive strategy modification engineering surfaces...
Biomaterials failures are frequently associated to the formation of bacterial biofilms on surface. The aim this work is study adhesion non motile bacteria streptococci consortium and Pseudomonas fluorescens. Substrates with micro nanopatterned topography were used. influence surface characteristics was investigated using optical epifluorescence microscopy, scanning electron microscopy (SEM) atomic force (AFM). Results showed an important substratum nature. On microrough surfaces, initial...
Arthroplasty is a highly successful treatment to restore the function of joint. The contamination implant via bacterial adhesion first step toward development device-associated infections. emerging concern about antimicrobial resistance resulted in growing interest develop alternative therapeutic strategies. Thus, increment incidence periprosthetic infections, complexity treating infections caused by organisms biofilms, together with rise antibiotic resistant bacteria, expose need design...
The increasing incidence of infections in implantable devices has encouraged the search for biocompatible antimicrobial surfaces. To inhibit bacterial adhesion and proliferation on biomaterials, several surface functionalization strategies have been developed. However, most these lead to bacteriostatic effect only few are able reach bactericidal condition. In this work, surfaces were designed through titanium with poly-l-lysine (PLL) as mediator incorporation silver nanoparticles (AgNPs)....
The use of implants in orthopedics and dental practice is a widespread surgical procedure to treat diverse diseases. However, peri-implantitis due infections and/or poor osseointegration can lead metallic implant failure. aim this study was develop multifunctional coating on titanium (Ti) surfaces, simultaneously deal with both issues, by combining antibacterial silver nanoparticles (AgNPs) regenerative properties lactoferrin (Lf). A simple cost-effective methodology that allows the direct...
Bacterial adhesion and spreading on biomaterials are considered key features of pathogenicity. Roughness topography the substrate have been reported to affect bacterial adhesion, but little is known about their effect spreading. Submicron row channel tuning with diameter (S2) were designed test motility these surfaces. Random nanometer-sized structures (S1) used as controls. Optical microscopy AFM employed detect biological surface pattern details in micro- nanoscale, respectively. Results...
The 33-mer gliadin peptide, is a highly immunogenic peptide involved in celiac disease and probably other immune pathologies associated to gliadin. spontaneous self-assembly of water reported, providing better insight into oligomers morphology secondary structure.
The control of multidrug-resistant (MDR) bacteria is a growing public health problem, and new strategies are urgently needed for the infections caused by these microorganisms. Notoriously, some MDR microorganisms generate complex structures or biofilms, which adhere to surfaces confer extraordinary resistance properties that fundamental challenges infections. One promising antimicrobial photodynamic therapy (aPDT), takes advantage suitable photosensitizers (PS), oxygen radiation eradicate...
Molecular diagnostic methods to detect and quantify viral RNA in clinical samples rely on the purification of genetic material prior reverse transcription polymerase chain reaction (qRT-PCR). Due large number processed laboratories, automation has become a necessity order increase method processivity maximize throughput per unit time. An attractive option for isolating is based magnetic solid phase separation procedure (MSPS) using microparticles. This offers advantage over other alternative...
An electrochemical method for self-assembling melanin films on the Au(111) surface from aggregates in alkaline media is reported. Electrochemical data combined with scanning tunneling microscopy (STM), atomic force microscopy, and Auger electron spectoscopy show that amount structure of deposited film depend potential (E) applied to interface deposition time. Film formation takes place at a noticeable rate E = −1.0 V (vs SCE). High-resolution STM images early stages growth small particles,...
Changes in the topography of Cu electrodeposits grown on polycrystalline substrates at low constant current density from still aqueous concentrated CuSO4 + H2SO4 solutions, 298 K, were studied by scanning force microscopy (SFM) different scale lengths (L) nanometer level upward. The dynamic scaling theory applied to SFM images leads exponents α = 0.87 ± 0.06 and β 0.63 0.08, which are consistent with an interface growing under unstable regime. For similar conditions, addition...
A new method for direct patterning of metal surfaces with sub‐50 nm resolution based on molecular films is described (see Figure). Thermal vapor deposition different metals chemically surface‐modified nanostructured silicon or metallic masters allows pattern transfer and easy film detachment. Patterned are also used as platforms to grow hybrid materials by controlled chemical reactions.
Pattern transfer with high resolution is a frontier topic in the emerging field of nanotechnologies. Electrochemical molding possible route for nanopatterning metal, alloys and oxide surfaces simple inexpensive way. This method involves electrodeposition onto conducting master covered by self-assembled alkanethiolate monolayer (SAMs). molecular film enables direct surface-relief pattern from to inner face electrodeposit, also allows an easy release electrodeposited due their excellent...
Commercial LaAlO3 substrates were thermally cycled simulating a procedure similar to those followed during TiO2 and SnO2 dilute magnetic semiconductors’ film pulsed laser deposition. Ferromagneticlike behavior was found in some substrates, which metallic iron impurities detected by x-ray photoelectron spectroscopy total reflection fluorescence measurements. A thorough experimental investigation, using high resolution techniques, showed that these introduced the used fix oven silicon holders....
This paper describes bacterial organization on nano/micropatterned surfaces with different chemical properties, which show interactions the biological systems (inert, biocompatible, and bactericide). These were prepared by molding techniques exposed to Pseudomonas fluorescens (P. fluorescens) cultures. Results from atomic force microscopy optical imaging demonstrate that structure of P. aggregates is strongly dependent surface topography while there no clear linking physical-chemical...
Microbial related contamination is of major concern and can cause substantial economic losses. Photodynamic inactivation (PDI) has emerged as a suitable approach to inhibit microorganism proliferation. In this work, PDI induced by 6-carboxypterin (Cap), biocompatible photosensitizer (PS), was analyzed. The growth inhibition Staphylococcus aureus exposed artificial UV-A radiation sunlight in the presence Cap investigated. After irradiation, 50 μM able decrease three orders (with respect...