Patrick Young

ORCID: 0000-0003-1705-5991
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About
Contact & Profiles
Research Areas
  • Stellar, planetary, and galactic studies
  • Gamma-ray bursts and supernovae
  • Astro and Planetary Science
  • Astronomy and Astrophysical Research
  • Pulsars and Gravitational Waves Research
  • Astrophysics and Cosmic Phenomena
  • Nuclear physics research studies
  • Astrophysics and Star Formation Studies
  • Astrophysical Phenomena and Observations
  • Planetary Science and Exploration
  • Inflammatory mediators and NSAID effects
  • Synthesis and Reactions of Organic Compounds
  • Neutrino Physics Research
  • Synthesis and Biological Evaluation
  • Astronomical and nuclear sciences
  • Space Exploration and Technology
  • Synthesis and biological activity
  • Historical Studies and Socio-cultural Analysis
  • Carbohydrate Chemistry and Synthesis
  • Solar and Space Plasma Dynamics
  • Cultural Identity and Heritage
  • French Historical and Cultural Studies
  • Synthesis of Organic Compounds
  • Adventure Sports and Sensation Seeking
  • Paleontology and Stratigraphy of Fossils

Arizona State University
2014-2023

Wingate University
2012-2023

University of New Hampshire
2023

University of New Hampshire at Manchester
2023

University of Massachusetts Lowell
2009-2022

Max Planck Society
2018

Los Alamos National Laboratory
2005-2011

University of Arizona
2001-2010

Stockholm University
1994-2010

Earth and Space Research
2008-2010

Zileuton [N-(1-benzo[b]thien-2-ylethyl)-N-hydroxyure] inhibited 5-hydroxyeicosatetraenoic acid synthesis by rat basophilic leukemia cell 20,000 x g supernatant and polymorphonuclear leukocytes (PMNL) (IC50 = 0.5 0.3 microM) respectively. It also leukotriene (LT)B4 biosynthesis PMNL 0.4 microM), human whole blood 0.9 microM). Inhibition of LTB4 was removed readily a simple wash procedure. At concentrations up to 100 microM, the compound produced little or no inhibition several related...

10.1016/s0022-3565(25)23086-5 article EN Journal of Pharmacology and Experimental Therapeutics 1990-03-01

Abstract Sirius, the seventh-nearest stellar system, is a visual binary containing metallic-line A1 V star Sirius A, brightest in sky, orbited 50.13 year period by B, and nearest white dwarf (WD). Using images obtained over nearly two decades with Hubble Space Telescope ( HST ), along photographic observations covering almost 20 years 2300 historical measurements dating back to 19th century, we determine precise orbital elements for binary. Combined parallax motion of A component, these...

10.3847/1538-4357/aa6af8 article EN The Astrophysical Journal 2017-05-08

We provide a set of stellar evolution and nucleosynthesis calculations that applies established physics assumptions simultaneously to low- intermediate-mass massive star models. Our goal is an internally consistent comprehensive nuclear production yield data base for applications in areas such as pre-solar grain studies. non-rotating models assume convective boundary mixing where it has been adopted before. include 8 (12) initial masses $Z = 0.01$ ($0.02$). Models are followed either until...

10.3847/0067-0049/225/2/24 article EN The Astrophysical Journal Supplement Series 2016-08-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives: inhibitors of immune complex induced inflammationFortuna Haviv, James D. Ratajczyk, Robert W. DeNet, Francis A. Kerdesky, Roland L. Walters, Steven P. Schmidt, H. Holms, Patrick R. Young, and George CarterCite this: J. Med. Chem. 1988, 31, 9, 1719–1728Publication Date (Print):September 1, 1988Publication History Published online1 May 2002Published inissue 1 September...

10.1021/jm00117a010 article EN Journal of Medicinal Chemistry 1988-09-01

We compare a suite of 3D explosion calculations and stellar models incorporating advanced physics with observational constraints on the progenitor Cassiopeia A. consider binary single stars from 16 to 40 solar masses range energies geometries. The parameter space allowed by observations nitrogen rich high velocity ejecta, ejecta mass, compact remnant 44Ti 56Ni abundances individually as an ensemble is considered. A 15-25 which loses its hydrogen envelope interaction undergoes energetic can...

10.1086/500108 article EN The Astrophysical Journal 2006-03-27

We compile spectroscopic abundance data from 84 literature sources for 50 elements across 3058 stars in the solar neighborhood, within 150 pc of Sun, to produce Hypatia Catalog. evaluate variability spread measurements reported same star by different surveys. also explore likely association Galactic disk, corresponding observation and determination methods all catalogs Hypatia, influence specific on overall trends, effect normalizing abundances scale. The resulting large number stellar...

10.1088/0004-6256/148/3/54 article EN The Astronomical Journal 2014-08-18

Although there is strong support for the collapsar engine as power source of long‐duration gamma‐ray bursts (GRBs), we still do not definitively know progenitor these explosions. Here review current set scenarios GRBs and observational constraints on scenarios. Examining models, find that single stars cannot be only GRBs. Several binary progenitors can match solid also have potential to trends are currently seeing in observations. Type Ib/c supernovae likely produced primarily binaries;...

10.1086/523768 article EN Publications of the Astronomical Society of the Pacific 2007-11-01

We compare the yields of Ti44 and Ni56 produced from post-processing thermodynamic trajectories three different core-collapse models -- a Cassiopeia A progenitor, double shock hypernova rotating 2D explosion with exponential power-law trajectories. The peak temperatures densities achieved in these span several distinct nucleosynthesis regions we identify, resulting trends for mass elements. fraction profiles generally explain tendencies post-processed yields, depending on which are traversed...

10.1088/0067-0049/191/1/66 article EN The Astrophysical Journal Supplement Series 2010-10-25

In recent years, an increasing number of proper motions have been measured for Galactic X-ray binaries. When supplemented with accurate determinations the component masses, orbital period, and donor effective temperature, these kinematical constraints harbor a wealth information on system's past evolution. Here, we consider all this available to reconstruct full evolutionary history black hole binary XTE J1118+480, assuming that system originated in disk has solar metallicity. This analysis...

10.1088/0004-637x/697/2/1057 article EN The Astrophysical Journal 2009-05-08

The AB Dor Moving Group consists of a "nucleus" ~10 stars at d ~ 20 pc, along with dozens purported "stream" members distributed across the sky. We perform chemical and kinematic analysis subsample stream to test whether they constitute physical stellar group. use NEMO Galactic code investigate orbits members, abundance using high resolution spectra taken Magellan Clay 6.5-m telescope. Using chi^2 measured abundances for 10 different elements, we find that only half could possibly...

10.1088/0004-637x/766/1/6 article EN The Astrophysical Journal 2013-02-28

ABSTRACT Stellar elemental abundances are important for understanding the fundamental properties of a star or stellar group, such as age and evolutionary history, well composition an orbiting planet. However, abundance measurement techniques have progressed, there has been little standardization between individual methods their comparisons. As result, different procedures determine measurements that vary beyond quoted error same elements within stars. The purpose this paper is to better...

10.3847/0067-0049/226/1/4 article EN The Astrophysical Journal Supplement Series 2016-08-31

We analyze stellar convection with the aid of three-dimensional (3D) hydrodynamic simulations, introducing turbulent cascade into our theoretical analysis. devise closures Reynolds-decomposed mean field equations by simple physical modeling simulations (we relate temperature and density fluctuations via coefficients); procedure (Convection Algorithm Based on Simulations) is terrestrially testable amenable to systematic improvement. develop a kinetic energy equation which contains both...

10.1088/0004-637x/690/2/1715 article EN The Astrophysical Journal 2008-12-30

The ideal exoplanets to search for life are those within a star's habitable zone. However, even the zone planets can still develop uninhabitable climate states. Sustaining temperate over geologic ($\sim$Gyr) timescales requires planet contain sufficient internal energy power planetary-scale carbon cycle. A major component of rocky planet's budget is heat produced by decay radioactive elements, especially $^{40}$K, $^{232}$Th, $^{235}$U and $^{238}$U. As ages these elements decay, this...

10.3847/2041-8213/ac6596 article EN cc-by The Astrophysical Journal Letters 2022-05-01

Abstract Stars and their associated planets originate from the same cloud of gas dust, making a star’s elemental composition valuable indicator for indirectly studying planetary compositions. While connection between iron (Fe) abundance presence giant exoplanets is established, relationship with small remains unclear. The elements Mg, Si, Fe are important in forming planets. Employing machine learning algorithms like XGBoost, trained on abundances (e.g., Hypatia Catalog) known...

10.3847/1538-3881/adbbb5 article EN cc-by The Astronomical Journal 2025-03-20

The hydroxamic acid functionally can be incorporated into simple molecules to produce potent inhibitors of 5-lipoxygenase. ability many these hydroxamates inhibit leukotriene synthesis in vivo has been measured directly with a rat peritoneal anaphylaxis model. Despite their enzyme inhibitory activity vitro, orally dosed acids only weakly inhibited vivo. This discrepancy is attributable at least part the rapid metabolism corresponding carboxylic acids, which are inactive against enzyme. A...

10.1021/jm00394a032 article EN Journal of Medicinal Chemistry 1987-11-01

The results of a 3-dimensional SNSPH simulation the core collapse 23 solar mass star are presented. This did not launch an explosion until over 600ms after collapse, allowing ideal opportunity to study evolution and structure convection below accretion shock late times. late-time allows us several recent claims in literature about role convection: is it dominated by l=1 mode driven vortical-acoustic (or other) instability, does produce strong neutron kicks, and, finally, key new mechanism?...

10.1086/513003 article EN The Astrophysical Journal 2007-04-17

While the 26S proteasome is a key proteolytic complex, little known about how levels are maintained in higher eukaryotic cells.Here we describe an RNA interference (RNAi) screen of Drosophila melanogaster that was used to identify transcription factors may play role maintaining proteasome.We RNAi library against 993 factor genes whose suppression Schneider 2 cells stabilized ubiquitin-green fluorescent protein reporter protein.This identified Cnc (cap 'n' collar [CNC]; basic region leucine...

10.1128/mcb.00799-10 article EN Molecular and Cellular Biology 2010-12-14

{\tau} Ceti (HD10700), a G8 dwarf with solar mass of 0.78, is close (3.65 pc) sun-like star where 5 possibly terrestrial planet candidates (minimum masses 2, 3.1, 3.5, 4.3, and 6.7 Earth masses) have recently been discovered. We report abundances 23 elements using spectra from the MIKE spectrograph on Magellan. Using stellar models determined here, we calculate position classical habitable zone time. At current best fit age, 7.63 Gy, up to two planets (e f) may be in zone, depending...

10.1088/0004-637x/803/2/90 article EN The Astrophysical Journal 2015-04-21

RULES FOR NOMENCLATURE IN TOMATO GENETICS: Including a List of Known Genes Get access D. W. BARTON, BARTON Search for other works by this author on: Oxford Academic PubMed Google Scholar L. BUTLER, BUTLER J. A. JENKINS, JENKINS C. M. RICK, RICK P. YOUNG Journal Heredity, Volume 46, Issue 1, January 1955, Pages 22–26, https://doi.org/10.1093/oxfordjournals.jhered.a106504 Published: 01 1955

10.1093/oxfordjournals.jhered.a106504 article EN Journal of Heredity 1955-01-01

We examine contributions of second-order physical processes to the results stellar evolution calculations that are amenable direct observational testing. In first paper in series, we established baseline using only physics were common modern codes. this establish how much discrepancy between observations and models is due particular elements new areas mixing, diffusion, equations state, opacities. then consider impact uncertainties on maximum predictive accuracy achievable by a code. The Sun...

10.1086/426131 article EN The Astrophysical Journal 2005-01-10

The Sirius AB binary system has masses that are well determined from many decades of astrometric measurements. Because the well-measured radius and luminosity A, we employed TYCHO stellar evolution code to determine age accurately, at 225-250 Myr. Note this fit requires assumption solar abundance use new Asplund et al. primordial metallicity. No A's position is possible using old Grevesse & Sauval scale. B white dwarf parameters have also been accurately space observations, cooling could be...

10.1086/462419 article EN The Astrophysical Journal 2005-08-11

We present new reddening measurements toward the young supernova remnant Cassiopeia A using two techniques not previously applied to this object. Our observations of near-infrared [Fe ii] 1.257 μm and 1.644 lines show extinction be highly variable across remnant, increasing west south, consistent with previous radio X-ray observations. While absolute value AV as determined by is uncertain due conflicting calculations their intrinsic flux ratio, parts without optical comparatively higher...

10.1088/0004-637x/697/1/29 article EN The Astrophysical Journal 2009-04-30

We report extensive radial velocity measurements of the two giant components detached, 104 day period binary system Capella. Our highly accurate three-dimensional orbital solution based on all existing spectroscopic and astrometric observations including our own yields much improved masses for primary secondary 2.466 ± 0.018 M☉ 2.443 0.013 M☉, with relative errors only 0.7% 0.5%, respectively. The mass ratio is considerably closer to unity than previously believed, which has an impact...

10.1088/0004-637x/700/2/1349 article EN The Astrophysical Journal 2009-07-13
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