A5071666854- Aquaculture disease management and microbiota
- Vibrio bacteria research studies
- Venomous Animal Envenomation and Studies
- Bacteriophages and microbial interactions
- Antimicrobial Peptides and Activities
- Identification and Quantification in Food
- Microbial infections and disease research
- Aquatic life and conservation
- Immune Response and Inflammation
- Animal Virus Infections Studies
- Echinoderm biology and ecology
- Viral gastroenteritis research and epidemiology
- Mosquito-borne diseases and control
- Calpain Protease Function and Regulation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- interferon and immune responses
- Inflammasome and immune disorders
- Bacterial biofilms and quorum sensing
- Seaweed-derived Bioactive Compounds
- Aquaculture Nutrition and Growth
- Escherichia coli research studies
- Parasite Biology and Host Interactions
- Biomarkers in Disease Mechanisms
- Marine Bivalve and Aquaculture Studies
Jilin Agricultural University
2019-2024
Shandong University
2021-2024
Changchun University
2019-2021
Aeromonas veronii is an important pathogen causing freshwater fish sepsis and ulcer syndrome. An increasing number of cases have demonstrated its significance as aquatic zoonotic agent. The purpose this study was to ensure the safety products by evaluating infection status edible fish. In experiment, we isolated A. from several species apparently healthy fish, including Carassius auratus, Cyprinus carpio, Ctenopharyngodon idella, Silurus asotus. identified through bacterial staining, culture...
The constant increase in temperatures under global warming has led to a prolonged aestivation period for Apostichopus japonicus, resulting considerable losses production and economic benefits. However, the specific mechanism of not been fully elucidated. In this study, we first tried illustrate biological mechanisms from perspective gut microbiota metabolites. Significant differences were found aestivating adult A. japonicus (AAJSD group) compared with nonaestivating (AAJRT young (YAJRT...
Aeromonas veronii is one of the main pathogens causing freshwater fish sepsis and ulcer syndrome. More more cases have shown that it has become an important zoonotic aquatic agent. In this study, a A. TH0426 mutant strain (ΔlamB) with in-frame deletion removed nucleotides 10-1,296 lamB gene was firstly constructed to investigate its functions. The results showed LD50 value ΔlamB zebrafish mice 13.7-fold 5.6-fold higher than those wild-type strain, respectively. toxicity EPC cells 2.1-fold...
Aeromonas veronii is a zoonotic pathogen capable of causing sepsis and ulceration in freshwater fish. Recently, reports numerous cases indicate marked increase pathogenicity. Nonetheless, little known about the pathogenesis A. infections. In this study, an in-frame mutant vipB gene was generated to investigate its biological function. Deletion resulted significant 204.71-fold decrease LD50 against zebrafish 2-fold 4-fold reduction toxicity EPC cells at 1 h 2 infection, respectively. The...
Abstract Aeromonas veronii is an important zoonotic and aquatic agent. More more cases have shown that it has caused huge economic losses in the aquaculture industry addition to threatening human health. But reasons for increasing virulence of A. are still unclear. In order further understand increased , we conducted a comparative analysis genomes with different virulence. The revealed there multiple factors, such as those related fimbriae, flagella, toxins, iron ion uptake systems type II,...
Aeromonas veronii is one of the main pathogens causing freshwater fish sepsis and ulcer syndrome. This bacterium has caused serious economic losses in aquaculture industry worldwide, it become an important zoonotic aquatic agent. However, little known about molecular mechanism pathogenesis A. veronii. In this study, we first constructed unmarked mutant strain (ΔpreA) by generating in-frame deletion preA gene, which encodes a periplasmic binding protein, to investigate its role TH0426. Our...
Abstract Aeromonas veronii is an important zoonotic and aquatic pathogen. An increasing number of reports indicate that it has caused substantial economic losses in the aquaculture industry, addition to threatening human health. However, little known about its pathogenesis. Exploration new virulence factors A. would be helpful for further understanding Hence, we comparatively analyzed proteomes virulent, attenuated, avirulent strains using tandem mass tag (TMT) protein labeling found...
Abstract Aeromonas veronii is a significant pathogen that capable of infecting humans, animals, and aquatic animals. The type III secretion system (T3SS) intimately associated with bacterial pathogenicity. ascO gene an important core component T3SS in A. , but its function still unclear. TH0426 was deleted by using the pRE112 suicide plasmid to study function. results showed ability ∆ adhere invade EPC cells significantly reduced 1.28 times. toxicity mutant strain Δ consistently lower than...
Aeromonas veronii is a virulent fish pathogen that causes extensive economic losses in the aquaculture industry worldwide. In this study, strain of A. TH0426 was used to establish an vitro biofilm model. The results show biofilm-forming abilities were similar different media, peaking under conditions 20 °C and pH 6. Further, isobaric tags for relative absolute quantitation (iTRAQ)-based quantitative proteomics methods compare differential expression between planktonic cells. alterations 277...
Aeromonas veronii is an important pathogen found in various aquatic environments and products, posing a threat to public health. The Hanks-like serine/threonine protein kinase closely linked the pathogenesis of pathogenic bacteria, but exact role YihE A. remains still unknown. To study specific function kinase, we constructed knockout mutant yihE gene veronii. deletion resulted changes metabolism L-arginine-AMC acetic acid, as well enhanced resistance ampicillin kanamycin Additionally, ΔyihE...
Ras-related C3 botulinum toxin substrate protein (Rac2) is an important member of the Ras family. Rac has a variety biological functions and closely connected with cytoskeleton formation, cell signal transduction, adhesion apoptosis. In this study, to investigate function northern snakehead (Channa argus) Rac2, full-length cDNA sequence Rac2 gene was obtained by RACE based on differentially expressed fragment from SSH library head kidney established in previous its physicochemical...