A5101499751- Advanced Radiotherapy Techniques
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Medical Imaging Techniques and Applications
- Endometrial and Cervical Cancer Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Cancer Genomics and Diagnostics
- Lung Cancer Diagnosis and Treatment
- Healthcare and Venom Research
- Photodynamic Therapy Research Studies
- Cancer Research and Treatments
- Ovarian cancer diagnosis and treatment
- Cancer Cells and Metastasis
- Natural Compounds in Disease Treatment
- Myofascial pain diagnosis and treatment
- Medical Image Segmentation Techniques
- Asthma and respiratory diseases
- MRI in cancer diagnosis
- Immune Response and Inflammation
- Prostate Cancer Treatment and Research
- Medical Research and Treatments
- Advanced X-ray and CT Imaging
- Cervical Cancer and HPV Research
Jiangsu Cancer Hospital
2020
Qufu Normal University
2018
Columbia University
2010-2017
NewYork–Presbyterian Hospital
2017
Columbia University Irving Medical Center
2012-2016
Army Medical University
2016
Southwest Hospital
2016
Tianjin Third Central Hospital
2016
Tianjin Medical University
2016
Qingdao University
2015
3504 Background: We presented the prognostic (prog) impact of molecular markers (MM) on relapse free survival (RFS) stage II-III CC (ASCO proc 2009, 27, abstr. 4002). analyze now 8 same MM overall (OS) after in PETACC 3, an adjuvant trial with 3278 patients (pts). Methods: 1,564 blocks were prospectively collected, tumor (Tu) DNA extracted and assessed as described previously. Markers prog value was analysed by Cox regression for OS, multivariate analysis (MA) Kaplan-Meier estimates median...
Hepatocellular carcinoma (HCC) is one of the most common and malignant cancers. The HCC incidence gets a strong sexual dimorphism as men are major sufferers in this disaster. Although several studies have uncovered presentative correlation between axis androgen/androgen receptor (AR) incidence, mechanism still largely unknown. Cancer stem cells (CSCs) small subgroup cancer contributing to multiple tumors behaviors, which play an important role oncogenesis various cancers including HCC....
The geriatric nutritional risk index (GNRI) is associated with the prognosis of many diseases. However, association between GNRI and patients aged ≥65 years severe community-acquired pneumonia (SCAP) has not been studied. We aimed to evaluate prognostic value in elderly SCAP patients.This study retrospectively analyzed clinical data 346 from December 2013 September 2019. Patients were divided into 4 groups by GNRI. chi-square test or student's t was used compare differences groups. Logistic...
Objective This study was aimed at investigating the clinical efficacy and studying possible mechanism of FUS applications to treat cervical intraepithelial neoplasia 1 (CIN1).Methods a prospective study, in which 30 patients with CIN1 (28/30 were HPV positive) enrolled treated therapy by gynecologist. All followed up for 3 months after therapy. Telephone interviews, PAP smear, colposcopic examinations, biopsies HPVDNA tests performed assess safety effectiveness HPV-positive CIN1. The...
3505 Background: KRAS and BRAF activating mutations (mut) are frequent in colorectal cancer (CRC). Both genes act the ERK pathway, but they occur different CRC subtypes have prognostic implications, suggesting might entail disruptions signaling pathways. Methods: RNA extracted from 1378 formalin-fixed tissues was used for expression profiling on Affymetrix-based ALMAC platform Colorectal Cancer DSA. G12S, G13V, G13C, G13D, G12R, G13A, G12V, G12D, G12G, G12C, G12A, G12G mut V600 were...
The Feng Gou Zhen (sharp-hook acupuncture) as a traditional form of ancient acupuncture is said to be particularly effective for managing periarthritis shoulder. We conducted this randomized controlled trial evaluate the effectiveness an add-on compared conventional analgesics patients with PAS. 132 were randomly assigned in 1 : ratio either group receiving sharp-hook plus acupoint injection or control group. Patients from both groups evaluated at week 0 (baseline), 1, and 4. primary outcome...
Bevacizumab (BV) is broadly used to treat a number of cancers; however, BV resistance mechanisms and strategies overcome this are yet be determined.We established xenograft mice models harboring Kirsten rat sarcoma oncogene homolog (KRAS) mutations based on the A549 cell line, tested responses tumors series drugs in ex vivo experiments. Changes transcriptive level were analyzed by ribonucleic acid (RNA) sequencing expressions connexins determined immunohistochemistry staining.A549 mutation...
Prostate brachytherapy is an effective treatment for early prostate cancer. The success depends critically on the correct needle implant position. We have devised automatic shape-based 3D level set segmentation tool tracking in trans-rectal ultrasound (TRUS) images, which uses shape information and technique to localize position estimate endpoint of real-time. Automatic initialization image not trivial. assume that most likely at with highest intensity a TRUS difference subtraction prior...
436 Background: Pancreatic ductal adenocarcinoma (PDAC) carries a poor prognosis, with significant morbidity and mortality from local progression. Radiotherapy can be administered for control, stereotactic body radiotherapy (SBRT) increasingly being utilized. We aim to compare the toxicity of SBRT intensity-modulated (IMRT) in this setting. Methods: A retrospective analysis patients PDAC receiving IMRT or at our institution between April 2011 November 2015 was performed. 81 were identified....
Pancreatic cancer is one of the most common human cancers with very low survival rate. So far, difficulties to make early diagnosis and find curative therapy for this malignant disease remain challenging. Considering Chinese medicine a long history clinical application in treating various diseases, it has been now introduced into anti-cancer treatment begun attract attentions researchers worldwide. Here, we summarize recent studies on anti-tumor activity pancreatic potential molecular...
Purpose: To use recursive cluster analysis to filter noises and artifacts out of useful signals. The method was applied CT or CBCT for preserving interested low Hounsfield Unit (HU) signals such as lung tissues while the HU is often overlapped with (or CBCT) artifacts. Methods: Cluster search similarity among data points, which could employ multi‐dimensional techniques. For our purpose, we searched a robust, fast, automatic process sorting object in CT, Therefore, 1‐D suitable purpose....
Objective To discuss the correlation between nasal administration of vitamin D3 and immunoglobulin (Ig) G4 IgE in patients with allergic rhinitis (AR) , study effect on immune mechanism AR. Methods Thirty AR whose skin prick test (SPT) were positive selected as observation group, 30 simple septum deviation SPT negative control group. All treated 300 000 U administration, once a week 4 times total. Seven days after treatment, serum concentrations IgG4 measured by lightscattering...
Purpose: Respiration‐correlated CBCT reduces respiratory motion artifacts at the cost of increased view‐aliasing due to gaps in projection data that are sorted other phases. Respiratory‐gated acquisitions can cover full scanning range but is inefficient (∼5 minutes per phase). In this study, we developed a 4D acquisition method using phase predication technique potentially acquire for each within clinically acceptable (∼10 or less) time. Methods: The proposed continuously scans target until...