A5088908664- Antimicrobial agents and applications
- Extraction and Separation Processes
- Inorganic and Organometallic Chemistry
- Organometallic Compounds Synthesis and Characterization
- Antimicrobial Peptides and Activities
- Metal complexes synthesis and properties
- Dental materials and restorations
- Synthetic Organic Chemistry Methods
- Biopolymer Synthesis and Applications
- biodegradable polymer synthesis and properties
- Ionic liquids properties and applications
- Chemical and Physical Properties in Aqueous Solutions
- Advanced Polymer Synthesis and Characterization
- Molecular Junctions and Nanostructures
Warsaw University of Technology
2016-2024
Cationic polymers have been extensively investigated as a potential replacement for traditional antibiotics. Here, we examined the effect of molecular weight (MW) on antimicrobial, cytotoxic, and hemolytic activity linear polytrimethylenimine (L-PTMI). The results indicate that biological polymer sharply increases MW increases. Thanks to different position antibacterial toxicity thresholds, tuning PTMI allows one achieve therapeutic window between antimicrobial concentrations. L-PTMI...
Polymeric antimicrobial agents are intensively investigated as potential novel antibiotics. In this work we use copolymerization of 2-propyl-2-oxazine (PrOzi) and 2-methyl-2-oxazoline (MeOx) combined with hydrolysis the polymer side chains a tool to obtain various linear polymeric derivatives polytrimethylenimines (L-PTMI) polyethylenimine (L-PEI). To well-defined polymers, initially determined rates, subsequently, hydrolytic rates repeating units, namely PrOzi, MeOx, 2-methyl-2-oxazine...
Antibacterial polylactide film composed of commercial PLA and block copolymer lactide linear polyethyleneimine (L-PEI) has been prepared. To observe complete inhibition bacterial growth only 1.1 wt% L-PEI is required.