A5058244949- Muscle activation and electromyography studies
- Cardiomyopathy and Myosin Studies
- Sports Performance and Training
- Muscle Physiology and Disorders
- Lower Extremity Biomechanics and Pathologies
- Cardiovascular Effects of Exercise
- Sports injuries and prevention
- Knee injuries and reconstruction techniques
- Advanced Sensor and Energy Harvesting Materials
- Motor Control and Adaptation
- Effects of Vibration on Health
- Foot and Ankle Surgery
- Neuroscience and Neural Engineering
- Force Microscopy Techniques and Applications
- Winter Sports Injuries and Performance
- Nuclear Structure and Function
- Tendon Structure and Treatment
- Prosthetics and Rehabilitation Robotics
University of Arizona
2025
University of Münster
2023-2024
Alphabet (United States)
2023
University of Calgary
2018-2023
Czech Academy of Sciences, Institute of Physiology
2023
Augenstern
2023
Many attempts have been made to determine the contribution of individual muscles in an agonistic group mechanics joints. However, previous approaches had limitations that often could not be controlled a precise manner, activated individually, and muscle contributions measured actively contracting group. Here, we introduce surgical approach allows for activation The is illustrated vastus lateralis (VL), medialis (VM) rectus femoris (RF) rabbit quadriceps We provide exemplar results potential...
This study aimed to examine whether muscle force and tendon stiffness in a muscle-tendon complex alter synchronously following 8-week whole-body vibration (WBV) training older people. Forty women aged 65 years were randomly assigned into control (CON, n = 15) groups (exposure time, 13; intensity, 12). For the groups, 4-week detraining period was completed period. Throughout training/detraining period, of medial gastrocnemius (MG) Achilles assessed four times (0, 4, 8, 12 weeks) using...
Agonistic muscles lose approximately 20% of their individual torque generating capacity when activated with agonistic compared to stimulated in isolation. In this study, we (i) tested if loss was accompanied by a corresponding force, thereby testing the potential role changes moment arms between conditions; (ii) removed all inter-muscular connections quadriceps muscles, thus determining force transmission; and (iii) systematically changed pressure performing experiments at different...
Sarcomere lengths are non-uniform on all structural levels of mammalian skeletal muscle. These non-uniformities have been associated with a variety mechanical properties, including residual force enhancement and depression, creep, increased capacity, extension the plateau force-length relationship. However, nature sarcomere length has not explored systematically. The purpose this study was to determine properties in active passive Single myofibrils rabbit psoas ( n = 20; 412 individual...
Abstract In striated muscle, the sarcomeric protein myosin-binding protein-C (MyBP-C) is bound to myosin thick filament and predicted stabilize heads in a docked position against filament, which limits crossbridge formation. Here, we use homozygous Mybpc2 knockout (C2 -/- ) mouse line remove fast-isoform MyBP-C from fast skeletal muscle then conduct mechanical functional studies parallel with small-angle X-ray diffraction evaluate myofilament structure. We report that C2 −/− fibers present...
Vastus medialis (VM) weakness is thought to alter patellar tracking, thereby changing the loading of patellofemoral joint (PFJ), resulting in pain. However, it challenging measure VM force and human studies, nor possible associated mechanical changes PFJ. To obtain fundamental insight into its effects on PFJ mechanics, authors determined presence experimentally simulated weakness. Skeletally mature New Zealand White rabbits were used (n = 6), vastus lateralis, VM, rectus femoris stimulated...
Tendon elasticity is an important factor affecting muscle function and thus human movements. It has been reported that the mechanical properties of tendon are adaptable to external loading condition. Based on adaptability conditions, one can assume there might be optimum ratio between strength stiffness. The present study aimed investigate whether correlation plantar flexor stiffness achilles (AT). Twenty two male subjects (age: <TEX>$23.2{\pm}1.5yrs$</TEX>, height:...
The purpose of this study was to quantify the contribution individual quadriceps muscles patellar tracking. and/or combined were activated in rabbits (n = 6) during computer-controlled flexion/extension knee. Three-dimensional tracking measured for vastus lateralis, medialis, and rectus femoris when alone simultaneously at different frequencies, producing a range knee extensor torques. Patellar changed substantially as function torque differed between muscles. Specifically, all...
Abstract In striated muscle, some sarcomere proteins regulate crossbridge cycling by varying the propensity of myosin heads to interact with actin. Myosin-binding protein C (MyBP-C) is bound thick filament and predicted stabilize in a docked position against limit formation, so-called OFF state. Via an unknown mechanism, MyBP-C thought release into ON state, where they are more likely form crossbridges. To study this proposed we used C2 -/- mouse line knock down fast-isoform completely total...