- Advanced Data Compression Techniques
- Design Education and Practice
- Electrocatalysts for Energy Conversion
- Video Coding and Compression Technologies
- Electrochemical Analysis and Applications
- Advanced Vision and Imaging
- CO2 Reduction Techniques and Catalysts
- Advanced Thermodynamics and Statistical Mechanics
- Online and Blended Learning
- Radical Photochemical Reactions
- Ionic liquids properties and applications
- Video Analysis and Summarization
- Ethics in medical practice
- Advancements in Battery Materials
- Ammonia Synthesis and Nitrogen Reduction
- Advanced Thermoelectric Materials and Devices
- Impact of Technology on Adolescents
- Carbon dioxide utilization in catalysis
- Educational Reforms and Innovations
- Hedgehog Signaling Pathway Studies
- Advanced battery technologies research
- Educational Technology and Assessment
- Thermal Radiation and Cooling Technologies
- Embedded Systems and FPGA Design
- Skin and Cellular Biology Research
Tokyo Institute of Technology
2023
Stanford University
2014-2022
Interface (United States)
2020-2022
SLAC National Accelerator Laboratory
2020-2022
Southwest University of Science and Technology
2022
Northwest A&F University
2020
Xi'an Jiaotong University
2020
Stanford Medicine
2020
Children's Hospital of Chongqing Medical University
2012
Chongqing University
2012
Patients with recessive dystrophic epidermolysis bullosa (RDEB) lack functional type VII collagen owing to mutations in the gene COL7A1 and suffer severe blistering chronic wounds that ultimately lead infection development of lethal squamous cell carcinoma. The discovery induced pluripotent stem cells (iPSCs) ability edit genome bring possibility provide definitive genetic therapy through corrected autologous tissues. We generated patient-derived COL7A1-corrected epithelial keratinocyte...
Aberrant Shh signaling promotes tumor growth in diverse cancers. The importance of is particularly evident medulloblastoma and basal cell carcinoma (BCC), where inhibitors targeting the pathway component Smoothened (Smo) show great therapeutic promise. However, emergence drug resistance limits long-term efficacy, mechanisms remain poorly understood. Using new models, we identify two distinct paradigms to Smo inhibition. Sufu mutations lead maintenance presence inhibitors. Alternatively...
Accurate theoretical simulation of electrochemical activation barriers is key to understanding electrocatalysis and guides the design more efficient catalysts. Providing a detailed picture proton transfer processes encounters several challenges: constant potential requirement during charge transfer, different time scales involved in processes, thermal fluctuation solvent. Hence, it prohibitively expensive computationally apply density functional theory (DFT) calculations modeling...
Bimetallic catalysts with optimal CO and C affinity for electrochemical reduction of 2 (eCO R) to high-value multi-carbon chemicals are identified by screening transition p-block metals complementary strong weak binding energy.
Understanding the bond strength of O* and OH* intermediates to metal-oxide surfaces is key predicting catalytic activity in oxygen-based electrochemistry. In this work, we uncover highly non-linear trends adsorption energies across 3d, 4d, 5d series MO2 transition-metal (TM) oxide computed within Hubbard-U corrected density functional theory (DFT + U). Investigating electronic structure with crystal orbital Hamiltonian populations (COHP) relevant metal–oxygen bonds reveals that...
Many breakthroughs have been achieved in rechargeable aluminum-ion battery technologies recent years. Most recently, operando X-ray diffraction (XRD) combined with density functional theory (DFT) calculations was reported to study the chloroaluminate anion (AlCl4-)-intercalated graphite cathode of battery. However, there are quite a few discrepancies between measured and simulated XRD patterns. This work is focused on simulation patterns intercalation compounds (GICs) DFT calculations. Our...
The contact between fine hydrophilic α-Al2O3 particles and nitrogen bubbles was studied as a function of solution composition in single bubble capture experiments, where the collection efficiency measured. surface charges both particle were controlled by varying electrolyte concentration pH solution. In all experiments negatively charged while either (above isoelectric point, pHIEP) or positively (below charged. found to be strongly influenced charge particles. maximum occurred when...
In an H.264 video encoder, motion estimation (ME) is the most time-consuming component. The ME process consists of two stages, integer pixel search and fractional search. Since complexity has been greatly reduced by numerous fast algorithms, computation overhead required become relatively significant. To reduce ME, we propose a prediction-based directional algorithm. We utilize more accurate vector predictions to achieve better reduction. further early termination method decrease amount...
A multistep electron transfer process is realized over C12A7:e − electride composite material. The graphene promotes from through surface Pd to the aryl halide substrates, affording a series of cross-coupling reactions.
Managing high heat flux is one of the greatest technical challenges integrated circuit (IC) industry facing because rising temperature limits device minimization and decreases its lifetime. In this paper, we report characterization cooling effect nanoscale Bi2Te3/Sb2Te3 multilayered thin films. The multilayer film was prepared with e-beam evaporation, had 21 layers (5-nm-thick each layer 105-nm-thick total). A thermoelectric film, which sandwiched between a diode sensor platinum sensor,...
This paper presents a novel motion estimation (ME) framework that offers fine-granular computational-complexity scalability. In the proposed framework, ME process is first partitioned into multiple search passes. A priority function used to represent distortion reduction efficiency of each pass. According predicted macroblock (MB), computational resources are then allocated effectively in progressive way achieve Experiments show our scheme achieves progressively improved performance over...
We studied the impact dynamics of a droplet on two types surfaces, i.e., nanostructured/hierarchical (NS/HS) with different extents hydrophobicity. It was found that contact time is related to wetting hysteresis. can be concluded hysteresis plays significant role in process bouncing drops based work done against resistance produced by angle (CAH). For similar surface roughness, CAH dominates, and lower creates smaller time. Compared NS energy stored during Cassie-Baxter/Wenzel state...
The phenomenon of cutting a class is increasingly more serious in university, leading to lot universities begin strengthen the daily management for students.The students attendance most common method.This paper introduces some can be used technology classroom attendance, through introduction technology, managers university have pointed choice students' management.
SUMMARY Tissue development results from lineage-specific transcription factors (TF) programming a dynamic chromatin landscape through progressive cell fate transitions. Here, we interrogate the epigenomic during epidermal differentiation and create an inference network that ranks coordinate effects of TF-accessible regulatory element-target gene expression triplets on lineage commitment. We discover two critical transition periods: surface ectoderm initiation keratinocyte maturation,...
Video applications in mobile devices call for low complexity video compression algorithms. This paper presents a 2-power transform compression. The elements of the matrix are all 2's low-order power. computation requires only 28 additions and 10 binary shifts. Computational analysis, coding gains RD curve comparison show that our is simpler than IntDCT ICT, while its efficiency similar to IntDCT, higher ICT much DT WHT. magnitude also avoids large memory consumption, problem many integer transforms.
Using an experimental pharmaceutical analysis course as example, we established a problem-oriented multidimensional teaching design that explored the three-body integrated mode in course.On basis of syllabus, various directions, including practical life, width, and depth direction, were used classroom practice carriers for analyzing solving problems.Practice results show design, which relies on problem-guided learning, increases interest systematicness experiment, compared to traditional...