A5049031308- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Surgical Sutures and Adhesives
- Tendon Structure and Treatment
- biodegradable polymer synthesis and properties
- Electrospun Nanofibers in Biomedical Applications
- CRISPR and Genetic Engineering
- Graphene and Nanomaterials Applications
- Bee Products Chemical Analysis
- Electrohydrodynamics and Fluid Dynamics
- Osteoarthritis Treatment and Mechanisms
- Knee injuries and reconstruction techniques
- Remote Sensing and LiDAR Applications
- Intestinal and Peritoneal Adhesions
- Microfluidic and Capillary Electrophoresis Applications
- Shoulder Injury and Treatment
- Bone and Dental Protein Studies
- Microfluidic and Bio-sensing Technologies
- Hernia repair and management
- Pluripotent Stem Cells Research
Shantou University
2021-2023
Chang Gung University
2014-2019
A desirable multi-functional nanofibrous membrane (NFM) for prevention of postoperative tendon adhesion should be endowed with abilities to prevent fibroblast attachment and penetration exert anti-inflammation effects. To meet this need, hyaluronic acid (HA)/ibuprofen (IBU) (HAI) NFMs were prepared by electrospinning, followed dual ionic crosslinking FeCl3 (HAIF NFMs) covalent 1,4-butanediol diglycidyl ether (BDDE) produce HAIFB NFMs. It is expected that the will act as a physical barrier...
Macroporous and biocompatible scaffolds for bone tissue engineering were prepared from 4% gelatin (G) gelatin/2% nanohydroxyapatite (nHAP), (GN), by cryogelation. The cryogels have interconnected pores with pore size around 100 μm a high degree of cross-linking. incorporation nHAP slightly reduced the porosity, crosslinking, swelling kinetics equilibrium water uptake, but enhanced toughness cryogel scaffolds. osteo-regeneration potential GN was further binding morphogenetic protein (BMP-2)...
Peritoneal adhesions are a common complication following pelvic and abdominal surgery, which could be reduced using anti-adhesion barriers. However, the shortcomings of existing hyaluronic acid (HA)-based film, such as rapid degradation rate poor operation ability, cannot ignored. The aim this study is to develop dual crosslinked electrospun HA nanofibrous membrane (NFM) with improved properties prolonged time an barrier film for preventing post-surgical peritoneal adhesions. NFMs were...
This study aims to prepare biphasic osteochondral scaffolds based on seamless joining of sintered polymer and polymer/ceramic microspheres for co-culture chondrocytes bone marrow stem cells (BMSCs). Poly(lactide-co-glycolide) (PLGA) 10% nanohydroxyapatite (nHAP)-incorporated PLGA (PGA/nHAP) were prepared through the oil-in-water precipitation method. Virgin (V) composite (C) from 250⁻500 µm PLGA/nHAP microspheres, respectively, while (OC) fabricated combination V C scaffolds....
Neurodegenerative disorders (NDs) including Alzheimer's Disease, Parkinson's Amyotrophic Lateral Sclerosis (ALS), and Huntington's disease are all incurable can only be managed with drugs for the associated symptoms. Animal models of human illnesses help to advance our understanding pathogenic processes diseases. Understanding pathogenesis as well drug screening using appropriate neurodegenerative diseases vital identifying novel therapies. Human-derived induced pluripotent stem cell (iPSC)...
Plasma separation is of high interest for lateral flow tests using whole blood as sample liquids. Here, we built a passive microfluidic device plasma with performance. This was made by filtration membrane and off-stoichiometry thiol-ene (OSTE) pillar forest. OSTE forest fabricated double replica moldings laser-cut polymethylmethacrylate (PMMA) mold, which has uniform microstructure. utilized to separate from samples used hydrophilic the capillary pump propel plasma. The can be purity later...
Existing nanofibrous based tissue engineering scaffolds are poor in cell infiltration and mechanical stability. Microsphere can be suggested as alternative for this problem. Poly (lactide-co-glycolide) (PLGA) with lactide to glycolide ratio 85:15 was used make virgin composite microsphere scaffolds. Nano Hydroxyapatite (nHAP) synthesized, characterized incorporated into microspheres 15% nHAP Microspheres of size range 250-500µm making three scaffold types; virgin, a combination...