A5006493859- Reproductive Health and Contraception
- Reproductive Biology and Fertility
- Menstrual Health and Disorders
- Renal and related cancers
- Endometriosis Research and Treatment
- Ovarian function and disorders
- Global Maternal and Child Health
- Adolescent Sexual and Reproductive Health
- Meta-analysis and systematic reviews
- Birth, Development, and Health
- Female Genital Mutilation/Cutting Issues
- Uterine Myomas and Treatments
- Ethics in Clinical Research
- Child and Adolescent Psychosocial and Emotional Development
- Delphi Technique in Research
- Sexual function and dysfunction studies
- Sperm and Testicular Function
- Homelessness and Social Issues
- Food Security and Health in Diverse Populations
- Youth Development and Social Support
- Prenatal Screening and Diagnostics
- Behavioral and Psychological Studies
- Genetics, Aging, and Longevity in Model Organisms
- Vaccine Coverage and Hesitancy
- Assisted Reproductive Technology and Twin Pregnancy
Family Health International 360
2018-2025
University of Maryland, Baltimore
2014-2024
University of North Carolina at Chapel Hill
2020
Johns Hopkins University
2011-2016
University of Baltimore
2015
Global efforts to improve menstrual health and sexual reproductive rights (SRHR) are fundamentally intertwined share similar goals for improving well-being increasing gender equality. Historically, however, the two fields have operated independently missed opportunities build upon their biological sociocultural linkages. Biological touchpoints connecting include genital tract infections, disorders, contraception, menopause. From a perspective, intersections occur in relation experience of...
Abstract While there is consensus that advanced maternal age (AMA) reduces oocyte yield and quality, the notion high FSH quality causes aneuploidy remains controversial, perhaps due to difficulties controlling confounding variables of levels. Here, contributions gonadotrophin elevation were separately controlled using a mouse model human female reproductive aging. Ovulated oocytes collected from young midlife mice after 0-, 2.6-, or 17-day treatment with analog equine chorionic (eCG), both...
Method-related concerns represent an important cause of contraceptive non-use and discontinuation. User preferences must be incorporated into the design new technologies to ensure product success improve family planning outcomes. We assessed among potential users in Burkina Faso Uganda for six methods currently under development or ready introduction: a copper intra-uterine device (IUD), levonorgestrel system, single-rod implant, biodegradable longer-acting injectable, method non-surgical...
A new family planning counseling tool uses the simple mnemonic device “NORMAL” to help counselors and providers communicate their clients key messages about menstrual bleeding changes associated with use of hormonal contraception copper IUD.
STUDY HYPOTHESISCellular aging of the egg following ovulation, also known as post-ovulatory aging, is associated with aberrant cortical mechanics and actomyosin cytoskeleton functions.
: Unmet need remains high in developing regions. New contraceptive technologies may improve uptake and use. This study examines desirable product characteristics.
Background: Contraceptive-induced menstrual changes (CIMCs) can affect family planning (FP) users' lives in both positive and negative ways, resulting opportunities consequences. Despite this, despite the important links between FP health (MH), neither field adequately addresses CIMCs, including research, product development, policies, programs globally. Methods: In November 2020, a convening of MH experts reviewed existing evidence on CIMCs identified significant gaps key areas. Results:...
Abstract Background Elevated FSH often occurs in women of advanced maternal age (AMA, ≥ 35) and infertility patients undergoing controlled ovarian stimulation (COS). There is controversy on whether high endogenous contributes to exogenous adversely impacts patient pregnancy rates. Methods The senescence-accelerated mouse-prone-8 (SAMP8) model female reproductive aging was employed assess the separate activity percentages (%) viable mature ovulated oocytes recovered after gonadotropin...
Women experience a series of specific transitions in their reproductive function with age. Shortening the menstrual cycle begins mid to late 30s and is regarded as first sign aging. Other early changes include elevation increased variance serum FSH levels, incidences oocyte spindle aberrations aneuploidy, declining fertility. The goal this study was investigate whether mouse strain senescence-accelerated mouse-prone-8 (SAMP8) suitable model for these midlife aging characteristics. Midlife...
ABSTRACT Despite the importance of menstruation and menstrual cycle to health, human rights, sociocultural economic wellbeing, study health suffers from a lack funding, research remains fractured across many disciplines. We sought systematically review validated approaches measure four aspects changes cycle—bleeding, blood, pain, perceptions—caus ed by any source used within field. then evaluated quality utility for clinical trials identified instruments. searched MEDLINE, Embase, instrument...
Abstract Objective We sought to develop consensus recommendations for improved measurement of contraceptive-induced menstrual changes (CIMCs) in contraceptive clinical trials build upon previous standardization efforts. Study Design undertook a virtual consensus-building process using modified Delphi approach, incorporating aspects Nominal Group Technique and the Jandhyala method. The consisted four half-day meetings, developing within five topical working groups, series questionnaires...
Abstract Women of advanced maternal age (AMA) (age ≥ 35) have increased rates infertility, miscarriages, and trisomic pregnancies. Collectively these conditions are called “egg infertility.” A root cause egg infertility is oocyte aneuploidy with age. AMA women often elevated endogenous FSH. Female senescence-accelerated mouse-prone-8 (SAMP8) has spindle aberrations, diminished fertility, rising FSH We hypothesize that during the oocyte's FSH-responsive growth period a abnormalities in...
<ns4:p><ns4:bold>Background</ns4:bold>: Unmet need remains high in developing regions. New contraceptive technologies may improve uptake and use. This study examines desirable product characteristics.</ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>: We added a module to the female questionnaire of PMA2020 surveys Burkina Faso Uganda conducted 50 focus group discussions (FGDs) with women, 10 FGDs men, 37 in-depth interviews (IDIs) providers across two countries. women IDIs included...
Women's concerns about contraceptive-induced menstrual changes can lead to method discontinuation and nonuse, contributing unmet need for contraception. Research on women's perceptions of amenorrhea related longer acting methods in low-income countries is limited.Data were from nationally representative household surveys focus group discussions with women reproductive age conducted Burkina Faso Uganda 2016-2017. Bivariate cross-tabulations multivariate logistic regression analyses used...
OPINION article Front. Glob. Womens Health, 07 September 2022Sec. Contraception and Family Planning https://doi.org/10.3389/fgwh.2022.992639