A5073532733- Cancer Immunotherapy and Biomarkers
- Cutaneous Melanoma Detection and Management
- COVID-19 and healthcare impacts
- Immunotherapy and Immune Responses
- Advanced Breast Cancer Therapies
- Breast Lesions and Carcinomas
- Inflammatory Biomarkers in Disease Prognosis
- Breast Cancer Treatment Studies
- Nutrition, Genetics, and Disease
- Cell Adhesion Molecules Research
- Melanoma and MAPK Pathways
Complexo Hospitalario Universitario A Coruña
2019-2025
Servicio Gallego de Salud
2019-2023
Universidade da Coruña
2020
Background: Anti-PD-1-based immunotherapy has improved outcomes in stage IIB to IV resected melanoma patients clinical trials. However, little is known about real-world outcomes, prognostic factors and patterns of relapse. Methods: This a retrospective multicenter observational study including with treated subsequent anti-PD-1-based adjuvant immunotherapy. Data on demographic characteristics, delivered treatment, factors, time pattern relapse were collected. Results: We included 245 from...
Abstract Since Coronavirus Disease 2019 (COVID-19) was declared pandemic in March 2020, there have been 545.226.550 cases up to 4 July 2022 (1). Several studies concluded that patients (pts) with cancer are at increased risk of COVID-19 infection, morbidity and mortality. Those undergoing neoadyuvant treatment particularly disease progression if chemotherapy or surgery delayed. Also, is known a higher NLR (neutrophil limphocyte ratio) related worse outcomes (3). Our hospital located the...
e21573 Background: PD-1 inhibitors improve outcomes in resected stage II-IV melanoma. However, recurrence patterns and prognostic factors are less known. Methods: We conducted a retrospective study melanoma patients (p) treated with adjuvant (clinical practice or clinical trials) from 5 centers. Demographic, disease characteristics, therapy, recurrence, treatment at relapse outcome were recorded. Descriptive assessment for analysis performed. Results: From June 2017 to 2022, 181 p included....
e13061 Background: Smoking is the leading cause of avoidable death in world. Although controversial for years, current prospective studies suggest that smoking increases risk cancer women with a deleterious BRCA1/2 mutation. Actually, we have very limited information about tobacco habit among carriers. Methods: We report an observational retrospective study consecutive sample 198 carriers studied between April 2014 and March 2018 at Family Cancer Clinic University Hospital Coruña (NW-Spain)....
Abstract Objectives: To evaluate the efficacy and cardiotoxicity profile of liposomal anthracycline or Carboplatin as part neoadjuvant therapy added to taxanes dual blockade in HER2-positive operable breast cancer patients. Methods: A total 60 patients diagnosed from August 2016 May 2019 were included study. The treatment consisted a sequential regimen non- pegilated (Myocet) plus trastuzumab pertuzumab, combination with carboplatin pertuzumab. clinical pathologic responses evaluated...