A5084818502- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Spondyloarthritis Studies and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Rheumatoid Arthritis Research and Therapies
- Sarcoidosis and Beryllium Toxicity Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Complement system in diseases
- Innovations in Medical Education
- Genital Health and Disease
- Dermatological and COVID-19 studies
- Drug-Induced Ocular Toxicity
- Primary Care and Health Outcomes
- T-cell and B-cell Immunology
- Hip disorders and treatments
- SARS-CoV-2 and COVID-19 Research
- Testicular diseases and treatments
- Urologic and reproductive health conditions
- Renal Diseases and Glomerulopathies
- Inflammatory Myopathies and Dermatomyositis
- Musculoskeletal Disorders and Rehabilitation
- Empathy and Medical Education
- Autoimmune Bullous Skin Diseases
- Peripheral Neuropathies and Disorders
Loma Linda University
2017-2024
Guru Gobind Singh Medical College and Hospital
2017-2023
University Health System
2022
Loma Linda University Medical Center
2017-2022
Riverside University Health System - Medical Center
2019-2022
University of California, Riverside
2019
Cedars-Sinai Medical Center
2015-2016
Center for Rheumatology
2013
St George's Hospital
2008
Background: Systemic Lupus Erythematosus (SLE) is an incurable autoimmune disorder with complement activation playing a key role in the pathogenesis of immune-mediated tissue injury. While quantifying to monitor SLE disease activity has been standard care since 1950s, decreased levels are not consistently associated flares. Objective: We seek clarify phenotype which deficiency causative, concomitant, or coincidental. Methods: A PUBMED literature review was conducted using words 'complement,'...
Objective The present study was undertaken to investigate prospective change in the prevalence of coronary microvascular dysfunction ( CMD ) and obstructive artery disease CAD a cohort subjects with systemic lupus erythematosus SLE initially evaluated for anginal chest pain CP ). Prior work documented relatively high absence . Methods Twenty female who underwent stress cardiac magnetic resonance imaging CMRI computed tomography angiography at baseline were reevaluated 5 years. Results...
ABSTRACT Inflammation driven by immune-mediated mechanisms can lead to a wide variety of skin manifestations. Cutaneous lupus erythematosus (CLE), for example, is an autoimmune connective tissue disease that may be limited the or part widespread multiorgan involvement seen in systemic erythematosus. Clinical findings are divided into lupus-specific (acute, subacute, and chronic) nonspecific lesions. The diagnosis CLE requires thorough physical examination and, some cases, biopsy laboratory...
Objective Lupus nephritis (LN) is a major cause of morbidity and mortality in systemic lupus erythematosus (SLE). Despite multiple studies addressing healthcare disparities, disparate outcomes LN persist. We investigate herein the association between socioeconomic status (SES) as well SES, SLE disease activity index (SLEDAI), treatment response. Methods Patients were selected from Southern California Registry (SCOLR), registry enrolling all-comers with SLE. Analysis was completed on...
The aim of this study is to identify rheumatology practice care gaps in evaluating for vitamin D deficiency systemic lupus erythematosus (SLE), as well adherence replacement SLE patients currently on corticosteroid therapy. Data were collected from the Southern California Lupus Registry addition data extraction medical health records. Evaluation serum level within 6 months patient encounter, current or prior use corticosteroids, and receiving therapy noted. Vitamin was defined 25(OH)D3 less...
Despite the evidence that complicated rheumatic diseases are more prevalent and severe in ethnic minorities, rheumatology research is afflicted with inadequate patient representation. It lacking socioeconomic diversity. The objective of this study to identify barriers enrollment propose possible solutions overcome these barriers. In study, 184 patients from two clinics (Safety Net clinic, a university-based clinic) were surveyed for concerns regarding participation clinical research....
Coexistence of systemic sclerosis and sarcoidosis is rare. Both have predominant lung manifestations, each with distinctive features on computed tomography (CT) the chest. We present herein a 52-year-old male limited manifested primarily by sclerodactyly subsequently shortness breath. A series CT scans chest were reviewed. Initial one year prior to onset revealed bilateral hilar right paratracheal, prevascular, subcarinal adenopathy. Five-year follow-up demonstrated thin-walled cysts,...
This study aimed to determine the baseline characteristics of a multi-ethnic systemic lupus erythematosus (SLE) cohort in Southern California established with intent addressing regional health inequity.Patients ≥18 years age SLE per Systemic Lupus International Collaborating Clinics (SLICC) criteria were recruited into Registry (SCOLR) if they resided San Bernardino and Riverside counties California. Individuals categorized according their stated ethnicity as non-Hispanic White, Hispanic,...
Coronary vasculitis is a rare, life-threatening complication of systemic lupus erythematosus (SLE).A 23-year-old woman with SLE presented typical angina and worsening dyspnoea on exertion. angiography revealed severe triple vessel disease 'string beads' appearance classic for coronary vasculitis. Transthoracic echocardiogram ejection fraction 25-30% severely hypokinetic distal septum anterior wall an akinetic apical wall. Despite treatment cyclophosphamide pulse-dose steroids, her did not...
Osteoporosis is a disease increasing in prevalence and growing public health concern. However, care gaps the diagnosis management of osteoporosis exist. One factors contributing to this observation may be that does not receive significant attention particularly during internal medicine residency training. A curriculum was designed implemented cohort Loma Linda University residents address issue. It consisted week-long rotation allowed enhance their knowledge recognition through participating...