A5051108835- Systemic Lupus Erythematosus Research
- Innovations in Medical Education
- Rheumatoid Arthritis Research and Therapies
- Musculoskeletal Disorders and Rehabilitation
- Systemic Sclerosis and Related Diseases
- Clinical Reasoning and Diagnostic Skills
- Ultrasound in Clinical Applications
- Infectious Diseases and Tuberculosis
- Autoimmune and Inflammatory Disorders Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Musculoskeletal synovial abnormalities and treatments
- Spondyloarthritis Studies and Treatments
- Pharmacological Effects of Natural Compounds
- Empathy and Medical Education
- Sarcoidosis and Beryllium Toxicity Research
- Meta-analysis and systematic reviews
- Atherosclerosis and Cardiovascular Diseases
- Inflammatory Myopathies and Dermatomyositis
- Pharmaceutical industry and healthcare
- Gout, Hyperuricemia, Uric Acid
- Radiology practices and education
- Dermatological and COVID-19 studies
- Immune Cell Function and Interaction
- Statistical Methods in Clinical Trials
- Hip disorders and treatments
Loma Linda University
2016-2025
University of California, Riverside
2019-2025
Amgen (United States)
2025
Loma Linda University Medical Center
2014-2023
VA Loma Linda Healthcare System
2016-2020
Riverside University Health System - Medical Center
2019
UMass Memorial Medical Center
2016
George E. Wahlen Department of VA Medical Center
2016
University of Utah
2016
Martingale Research (United States)
2016
To develop an Outcome Measures in Rheumatology (OMERACT) ultrasonography score for monitoring disease activity giant cell arteritis (GCA) and evaluate its metric properties.The OMERACT Instrument Selection Algorithm was followed. Forty-nine members of the large vessel vasculitis working group were invited to seven Delphi rounds. An online reliability exercise conducted using images bilateral common temporal arteries, parietal frontal branches as well axillary arteries from 16 patients with...
This study examines the relationship between psychosocial factors, ethnicity, disease activity and quality of life in systemic lupus erythematosus.One hundred twenty-five adult Caucasian Hispanic patients were recruited from four Southern California medical centers. Linear regression analysis was performed to assess correlation socioeconomic factors (age, income), (patient physician reported), as well psychological (depression, internality, helplessness) variables with (QOL) measured by...
Competitive pressure to maximize the current bibliometric measures of productivity is jeopardizing integrity scientific literature. Efforts are underway address ‘reproducibility crisis’ by encouraging use more rigorous, confirmatory methods. However, as long continues be defined number discoveries scientists publish, impact factor journals they publish in and times their papers cited, will reluctant accept high quality methods consistently conduct confirmatory/replication studies. This...
ABSTRACT Background Psychological safety (PS) is the perception that it safe to take interpersonal risks in work environment. In teaching hospitals, PS may influence clinical learning environment for trainees. Objective We assessed whether resident physicians believe they are psychologically safe, and if associated with how rate satisfaction their experience. Methods Data were extracted from Learners' Perceptions Survey (LPS) of residents who rotated through a Department Veterans Affairs...
To assess the association of industry funding with characteristics, outcome, and reported quality randomized controlled trials (RCTs) drug therapy for rheumatoid arthritis (RA).The Medline Cochrane Central Register Controlled Trials databases were searched to identify original RA RCTs published in 2002-2003 2006-2007. Two reviewers independently assessed each RCT source, outcome (positive [statistically significant result favoring experimental primary outcome] or not positive), reporting...
Systemic lupus erythematosus (SLE) is an autoimmune disease that can significantly impact both physiological and psychological functioning. In order to examine the relationship between functioning activity in SLE, we administered instruments collected sociodemographic information measured indices of psychosocial from 125 adult Hispanic White patients with SLE. Patients were recruited four healthcare settings greater Southern California area. Both cross-sectional longitudinal relationships...
Objectives The purpose of this study was to establish standards for musculoskeletal ultrasound competency through knowledge and skills testing using criterion‐referenced methods. Methods Two groups rheumatology fellows trained in a standardized curriculum, which required submission studies review over 8 months. Both then completed written practical examinations ultrasound. Instructors, advanced users, intermediate users served as comparison groups. A passing score (competency) established...
This study examined the contribution of pain and psychological distress to fatigue.One-hundred twenty-five adult Caucasian Hispanic lupus patients participated in this study. Demographic data, patient- physician-reported disease activity, as well functioning, were collected. Fatigue, pain, vitality measured using visual analogue scales a subscale SF-36 questionnaire. Linear hierarchical regression analyses conducted. In analysis, ethnicity was entered at first step, followed by age, income...
Systemic lupus erythematosus (SLE) predominantly affects women. Clinical phenotype and outcomes in SLE may vary by sex are further complicated unique concerns that dependent upon sex-defined roles. We aimed to describe differences disease-specific quality of life (QoL) assessment scores using the Lupus Patient-Reported Outcome (LupusPRO) tool a large international study.Cross-sectional data from 1,803 patients with on demographics, self-identified status, LupusPRO, disease activity were...
Objective To examine characteristics associated with the publication and timeliness of randomized controlled trials (RCTs) treatment rheumatoid arthritis (RA). Methods RA RCTs (phases II–IV) registered at ClinicalTrials.gov completed by December 31, 2009 were identified. A standardized strategy was used to determine status outcome assessment. The association RCT recorded study time assessed. Results search conducted least 30 months after trial completion revealed that among 143 eligible...
Musculoskeletal ultrasound (MSUS) in rheumatology the US has advanced by way of promotion certifications and standards use inclusion core fellowship curriculum. In order to inform endeavors for curricular integration, objectives present study were assess current program needs incorporation teaching methods that are being employed.A needs-assessment survey (S1) was sent 113 directors. For programs taught MSUS, a curriculum (S2) lead faculty. Programs stratified according size formal written...
Abstract Hyperinflammation and lymphopenia provoked by SARS-CoV-2-activated macrophages contribute to the high mortality of Coronavirus Disease 2019 (COVID-19) patients. Thus, defining host pathways aberrantly activated in patient is critical for developing effective therapeutics. We discovered that G9a, a histone methyltransferase overexpressed COVID-19 patients with viral load, activates translation specific genes induce hyperinflammation impairment T cell function or lymphopenia. This...
Objective Lupus nephritis (LN) is a major cause of morbidity and mortality in systemic lupus erythematosus (SLE). Despite multiple studies addressing healthcare disparities, disparate outcomes LN persist. We investigate herein the association between socioeconomic status (SES) as well SES, SLE disease activity index (SLEDAI), treatment response. Methods Patients were selected from Southern California Registry (SCOLR), registry enrolling all-comers with SLE. Analysis was completed on...
To examine the prevalence, types and temporal trends of reported financial conflicts interest (FCOIs) among authors drug therapy randomized controlled trials (RCTs) for RA their association with study outcomes.We identified original, non-phase 1, parallel-group, RCTs published in years 2002-03, 2006-07, 2010-11. Two investigators independently obtained trial characteristics data. Authors' FCOIs were classified as honoraria/consultation fees receipt, employee status, research grant, stock...