A5066407002- Vasculitis and related conditions
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Otitis Media and Relapsing Polychondritis
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Musculoskeletal synovial abnormalities and treatments
- Renal Diseases and Glomerulopathies
- Systemic Sclerosis and Related Diseases
- Cell Adhesion Molecules Research
- Urticaria and Related Conditions
- Atherosclerosis and Cardiovascular Diseases
- Peripheral Neuropathies and Disorders
- Orthopedic Surgery and Rehabilitation
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Inflammasome and immune disorders
- Viral Infections and Immunology Research
- Peripheral Nerve Disorders
- Ocular Diseases and Behçet’s Syndrome
- Occupational exposure and asthma
- Platelet Disorders and Treatments
- Musculoskeletal Disorders and Rehabilitation
Azienda Sanitaria Unità Locale di Reggio Emilia
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2014-2025
Ospedale Santa Maria
2014-2024
Santa Maria Nuova Hospital
2007-2023
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2022
University of Modena and Reggio Emilia
2018-2022
Azienda Ospedaliera S.Maria
1997-2021
Azienda Ospedaliero-Universitaria di Modena
2007-2020
Marche Polytechnic University
2019
University of Turin
2018
The objective of this study was to develop EULAR/ACR classification criteria for polymyalgia rheumatica (PMR). Candidate were evaluated in a 6-month prospective cohort 125 patients with new onset PMR and 169 non-PMR comparison subjects conditions mimicking PMR. A scoring algorithm developed based on morning stiffness >45 minutes (2 points), hip pain/limited range motion (1 point), absence RF and/or ACPA peripheral joint pain point). score ≥4 had 68% sensitivity 78% specificity discriminating...
Abstract The objective of this study was to develop European League Against Rheumatism/American College Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate were evaluated in a 6‐month prospective cohort 125 patients with new‐onset PMR and 169 non‐PMR comparison subjects conditions mimicking PMR. A scoring algorithm developed based on morning stiffness >45 minutes (2 points), hip pain/limited range motion (1 point), absence rheumatoid factor and/or...
To define the elementary ultrasound (US) lesions in giant cell arteritis (GCA) and to evaluate reliability of assessment US according these definitions a web-based exercise.Potential normal abnormal findings temporal extracranial large arteries were retrieved by systematic literature review. As subsequent step, structured Delphi exercise was conducted involving an expert panel Outcome Measures Rheumatology (OMERACT) Large Vessel Vasculitis Group agree appearance key vasculitis arteries. The...
The main objective of this study was to analyse the prevalence and characteristics subclinical GCA in patients with PMR.
To evaluate the frequency of visual manifestations at presentation in an Italian population-based cohort patients with biopsy-proven giant cell arteritis (GCA), and to investigate predictors for development permanent loss.We identified 136 Reggio Emilia (Italy) residents GCA diagnosed between 1986 2002. Medical records these were reviewed, demographic, clinical, laboratory data collected.Multivariate analysis multiple logistic regression models was performed identify best loss.Visual...
We studied the epidemiology of giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) in a Mediterranean population. Ninety-nine patients with PMR and/or GCA were identified over 9-year period (1980-1988) Reggio Emilia, Italy. The average annual incidence was 12.7/100,000 6.9/100,000, respectively, population aged 50 years or older. Frequencies HLA antigens determined 49 who followed by staff at our rheumatology unit during 1980-1988 period. When compared findings 242 healthy controls,...
Background: Evidence of a dark halo on ultrasonography has been considered specific sign giant-cell arteritis and may replace temporal artery biopsy for the diagnosis in patients with typical clinical manifestations. Objective: To assess usefulness duplex to compare this mode physical examination arteries suspected or polymyalgia rheumatica. Design: Diagnostic test study. Setting: Several divisions Reggio Emilia Hospital, Emilia, Italy. Patients: 86 consecutive rheumatica identified over...
Background: A reliable alternative to steroids for treating polymyalgia rheumatica has not yet been identified. Although infliximab used occasionally in steroid-resistant cases, its efficacy demonstrated a controlled study. Objective: To compare the of prednisone plus with that placebo patients newly diagnosed rheumatica. Design: Randomized, placebo-controlled trial. Setting: 7 rheumatology clinics Italy. Patients: 51 Patients associated giant cell arteritis and those who had previously...
To evaluate the impact of traditional cardiovascular risk factors, carotid atherosclerosis and effect anti-platelet/anti-coagulant therapy on occurrence severe cranial ischaemic events (CIEs) in GCA.We identified 180 Reggio Emilia (Italy) residents with biopsy-proven GCA diagnosed between 1986 2005. We evaluated data demographics, clinical features, laboratory investigations, use atherosclerosis.Systemic signs/symptoms were significantly less frequent (P = 0.004) ESR C-reactive protein (CRP)...
<h3>Objectives</h3> Skin and joint involvement in psoriasis (PsO) psoriatic arthritis (PsA) are thought to relate the so-called Koebner response. Given that dactylitis is non-randomly distributed digits, this study tested hypothesis accessory pulleys linked flexor tendons were thickened PsA thus exhibited koebnerisation. <h3>Methods</h3> Ninety-six subjects (27 PsA, 27 rheumatoid (RA), 23 PsO 19 healthy controls (HCs)) enrolled. The A1, A2 A4 pulley thickness was measured using a...
This study evaluated the frequency, timing, and characteristics of flares in a large cohort Italian patients with biopsy-proven giant cell arteritis (GCA) to identify factors at diagnosis able predict occurrence flares. We 157 transmural GCA diagnosed followed Rheumatology Unit Reggio Emilia Hospital (Italy) for whom sufficient information was available from time until least 4 years follow-up. Fifty-seven (36.5%) experienced ≥1 Fifty-one (46.4%) 110 total (88 relapses 22 recurrences) were...
Objective To define the role of ultrasound (US) for assessment patients with rheumatoid arthritis (RA) in clinical remission, including joint and tendon evaluation. Methods A multicentre longitudinal study has been promoted by US Study Group Italian Society Rheumatology. 25 centres participated, enrolling consecutive RA remission. All underwent complete (demographic data, disease characteristics, laboratory exams, 28 joints patient/physician-reported outcomes) Power Doppler (PD) evaluation...
Objective. The purpose of the ULISSE study was to evaluate prevalence clinical and ultrasonographic (US) entheseal involvement in patients with psoriatic arthritis (PsA), psoriasis, fibromyalgia syndrome (FMS). Methods. In this cross-sectional multicenter study, PsA psoriasis (not taking systemic therapy) FMS underwent a evaluation entheses, B-mode power Doppler examination 6 pairs entheses. Results. analyzed 140 PsA, 51 FMS. Clinical US examinations were performed 1960 1680 entheses group,...
To develop an Outcome Measures in Rheumatology (OMERACT) ultrasonography score for monitoring disease activity giant cell arteritis (GCA) and evaluate its metric properties.The OMERACT Instrument Selection Algorithm was followed. Forty-nine members of the large vessel vasculitis working group were invited to seven Delphi rounds. An online reliability exercise conducted using images bilateral common temporal arteries, parietal frontal branches as well axillary arteries from 16 patients with...
The aim of the present study was to determine clinical significance subclinical giant cell arteritis (GCA) in polymyalgia rheumatica (PMR) and ascertain its optimal treatment approach.
Objective To determine the frequency and characteristics of distal musculoskeletal manifestations in polymyalgia rheumatica (PMR). Methods Prospective followup study 177 consecutive patients meeting clinical criteria for PMR, diagnosed over a 5-year period 2 rheumatology secondary referral centers Italy. Results Seventy-nine (45%) had manifestations. Peripheral arthritis occurred 45 (25%), carpal tunnel syndrome 24 (14%), extremity swelling with pitting edema 21 (12%), tenosynovitis 5 (3%)....
To determine laboratory parameters that may be useful in identifying polymyalgia rheumatica (PMR) patients who require long-term corticosteroid therapy.A prospective followup study of 94 consecutive untreated with PMR were assessed for relapse/recurrence a mean 39 months. This cohort represented all the diagnosed over 4-year period 2 Italian secondary referral centers. Patients monitored clinical signs and symptoms, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), serum...
To evaluate the inflammatory involvement of cervical interspinous bursae in patients with polymyalgia rheumatica (PMR) using MRI.In all, 12 consecutive, untreated new PMR were investigated. Five fibromyalgia, two osteoarthritis and six spondyloarthritis neck pain served as controls. MRI spine was performed all case 13 control patients. Two four pelvic girdle also had lumbar spine.MRI evidence bursitis found PMR, three psoriatic spondylitis one osteoarthritis. A moderate to marked (grade...
To investigate the epidemiology and clinical course of Behçet's disease (BD) over a 17-year period in defined area northern Italy.All patients with incident BD diagnosed (from January 1, 1988 to December 31, 2004) living Reggio Emilia were identified through following sources: physicians at Hospital, medical practitioners, community-based specialists. We all registered centralized index district database for rare diseases. Patients followed up from time diagnosis until either their death or...
<h3>Objective</h3> To compare the performance of published classification/diagnostic criteria for polymyalgia rheumatica (PMR), including new 2012 European League Against Rheumatism (EULAR)/American College Rheumatology (ACR) criteria, in a single-centre study. <h3>Methods</h3> We studied all consecutive patients with new-onset PMR seen our centre over 6 years, whose diagnosis was confirmed during prospective 12-month follow-up period. Subjects were classified by each seven different...
Objective To assess the findings of contrast‐enhanced ultrasound (CEUS) carotid arteries in patients with large vessel vasculitis (LVV) and to compare them those observed using 18 F‐fluorodeoxyglucose–positron emission tomography ( FDG‐PET). Methods A total 31 consecutive LVV (14 Takayasu arteritis, 17 giant cell arteritis involvement) underwent both PET/computed artery color Doppler (CDUS) for a 35 combined assessments. Right CEUS was performed after CDUS all Kerr's criteria, complete...
Objective. The aim of this study was to assess the usefulness colour duplex sonography (CDS)-guided temporal artery biopsy (TAB) for diagnosis GCA in patients with suspected GCA.