A5082131925- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Musculoskeletal synovial abnormalities and treatments
- Gout, Hyperuricemia, Uric Acid
- Autoimmune and Inflammatory Disorders Research
- Bone and Joint Diseases
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Psoriasis: Treatment and Pathogenesis
- Osteoarthritis Treatment and Mechanisms
- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Orthopedic Infections and Treatments
- Pregnancy and Medication Impact
- Lymphadenopathy Diagnosis and Analysis
- Tendon Structure and Treatment
- Bone Metabolism and Diseases
- Dermatologic Treatments and Research
- Osteomyelitis and Bone Disorders Research
- Viral Infections and Immunology Research
- Venous Thromboembolism Diagnosis and Management
- Musculoskeletal Disorders and Rehabilitation
- Reproductive System and Pregnancy
- Dermatological and COVID-19 studies
- Dermatology and Skin Diseases
Ospedale San Carlo
2020-2025
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2022
Ospedale Madonna Delle Grazie
2018-2022
Azienda Ospedaliera Carlo Poma
2021-2022
University of Siena
2013-2017
Inserm
2017
University of Turin
2017
University of Pisa
2017
Hôpital Ambroise-Paré
2017
Instituto Nacional de Rehabilitación
2017
Objective To define the role of ultrasound (US) for assessment patients with rheumatoid arthritis (RA) in clinical remission, including joint and tendon evaluation. Methods A multicentre longitudinal study has been promoted by US Study Group Italian Society Rheumatology. 25 centres participated, enrolling consecutive RA remission. All underwent complete (demographic data, disease characteristics, laboratory exams, 28 joints patient/physician-reported outcomes) Power Doppler (PD) evaluation...
To define the ultrasonographic characteristics of calcium pyrophosphate crystal (CPP) deposits in joints and periarticular tissues to evaluate intra- interobserver reliability expert ultrasonographers assessment CPP deposition disease (CPPD) according new definitions.After a systematic literature review, Delphi survey was circulated among group ultrasonographers, who were members CPPD Ultrasound (US) Outcome Measures Rheumatology (OMERACT) subtask force, obtain definitions US at level...
To assess the reliability of OMERACT ultrasound (US) definitions for identification calcium pyrophosphate deposition disease (CPPD) at metacarpal-phalangeal, triangular fibrocartilage wrist (TFC), acromioclavicular (AC) and hip joints.A web-based exercise subsequent patient-based were carried out. A panel 30 members, participated by evaluating twice a set US images presence/absence CPPD. Afterwards, 19 members met in Siena, Italy, exercise. During exercise, all sonographers examined eight...
Treatment of rheumatoid arthritis (RA)-related interstitial lung disease (ILD) is challenging, and many conventional biologic disease-modifying anti-rheumatic drugs (DMARDs) have been associated with ILD development or progression. The aim this multicentric retrospective study was to analyze the evolution in Italian RA-ILD patients treated abatacept (ABA).All ABA for at least six months were retrospectively evaluated. Serology, previous concurrent therapies, chest high-resolution computer...
To investigate pregnancy outcomes in women with autoimmune rheumatic diseases (ARD) the Italian prospective cohort study P-RHEUM.it.
Objectives. This study aimed to estimate the prevalence of US-detected tenosynovitis in RA patients clinical remission and explore its correlates. Methods. A total 427 were consecutively enrolled from 25 Italian rheumatology centres. Tenosynovitis synovitis scored by US grey scale (GS) power Doppler (PD) semi-quantitative scoring systems at wrist hand joints. Complete assessment was performed rheumatologists blinded results. flare questionnaire used assess unstable (primary outcome), HAQ for...
The objectives of this study are to investigate the prevalence Baker's cyst (BC) in patients with knee pain, and assess correlation between BC severity osteophytes joint effusion. A retrospective was conducted on a group pain referred our outpatient clinic for ultrasonography January 2010 February 2011. Patients underwent an ultrasonographic exam knees presence marginal femorotibial osteophytosis, effusion BC. dichotomous score assigned each item (1 present, 0 absent) US signs osteoarthritis...
A common and well-documented feature of spondyloarthropathies is inflammation the peripheral enthesis1. Ultrasound (US) imaging useful when assessing enthesitis, many investigators have described its features2,3. A 50-year-old man with psoriasis developed morning stiffness, tenderness, swelling small joints in hands asymmetrically during last month. Clinical examination revealed tenderness proximal interphalangeal (PIP) second, third, fourth fingers …
Abstract A 7‐day‐old infant developed erythematous indurated plaques on the back, left shoulder, and arm a few days after therapeutic hypothermia. Ultrasonographic study along with Doppler blood flow analysis of lesional skin areas revealed flogistic fat involvement calcifications. On basis clinical appearance, patient history, ultrasonographic study, diagnosis subcutaneous necrosis newborn was established.
In this prospective observational study, data were collected from 34 rheumatology clinics in Italy patients with rheumatoid arthritis (RA), psoriatic (PsA) and axial spondyloarthritis (axSpA) who started golimumab (GLM) as a second anti-TNFα drug. The primary objective was to evaluate the effectiveness of GLM after 6 months. Changes quality life using EQ-5D-5L also assessed. A total 194 aged 53.2 ± 12 years anti-TNF drug: 39 (20.1%) RA, 91 (46.9%) PsA 64 (32.9%) axSpA. After months...
Objective. The objective of this study was to draw up a set recommendations for the format and content musculoskeletal ultrasonography (MSUS) report in rheumatology. Methods. A panel rheumatologists, members MSUS Study Group Italian Society Rheumatology, met order identify main discrepancies report. 15 then defined, aimed at resolving discrepancies. They consisted information about motivations examination, equipment, US modalities scanning technique, list examined structures findings,...
Interleukin 23 (IL-23) is a pro-inflammatory cytokine that plays protective role against bacterial and fungal infections. However, the dysregulation of IL-23/IL-17 axis provides solid substrate for development various inflammatory diseases, such as psoriatic arthritis (PsA) ankylosing spondylitis (AS).In different clinical trials, several drugs IL-23 have shown efficacy safety toward PsA, with excellent results on skin joint scores. same did not show in AS, suggesting may be relevant driver...
Ultrasonography (US) has been demonstrated to be an important tool in the diagnosis of calcium pyrophosphate (CPP) crystal deposition disease. The aim our study was individuate and describe possible pitfalls US detection such deposits menisci.We enrolled all patients waiting undergo knee replacement surgery due osteoarthritis, for one-month period. Each patient underwent examination knee, focusing on menisci. After surgery, menisci were examined by US, macroscopically microscopically, using...
Ultrasonography (US) is a relevant tool in the study of calcium pyrophosphate dihydrate (CPP) deposition disease. However, differential diagnosis hyperechoic deposits within fibrocartilage can be difficult; moreover, US limited by need an adequate acoustic window. We describe scanning technique that offers new viewpoint knee meniscal structure: longitudinal scan performed according to long axis meniscus. This proves particularly useful for identification CPP deposition, but could also...
Background . Bone damage in rheumatoid arthritis (RA) and psoriatic (PsA) includes an accelerated bone mineral density (BMD) reduction. The objective was to evaluate BMD variations of the metacarpophalangeal joints (MCPs) patients starting treatment with methotrexate (MTX) or etanercept. Methods Patients affected by RA PsA hand involvement moderate high disease activity, were enrolled this study. All underwent clinical examination, laboratory exams, a DXA scan most hand, as assessed...