A5051734690- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Pregnancy and Medication Impact
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Adipokines, Inflammation, and Metabolic Diseases
- Atherosclerosis and Cardiovascular Diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Psychosomatic Disorders and Their Treatments
- Eosinophilic Esophagitis
- Regulation of Appetite and Obesity
- Spondyloarthritis Studies and Treatments
- Peripheral Neuropathies and Disorders
- Monoclonal and Polyclonal Antibodies Research
- Renal Diseases and Glomerulopathies
- Rheumatoid Arthritis Research and Therapies
- Dermatological and COVID-19 studies
- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Galectins and Cancer Biology
- Diversity and Career in Medicine
- Diabetes and associated disorders
- Salivary Gland Disorders and Functions
- COVID-19 Clinical Research Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Immunodeficiency and Autoimmune Disorders
Campus Bio Medico University Hospital
2003-2024
Università Campus Bio-Medico
2009-2023
Center for Rheumatology
2005-2017
Medizinisches Versorgungszentrum Prof. Mathey, Prof. Schofer
2017
University of Bari Aldo Moro
2003
Sapienza University of Rome
2002
The authors assessed the prevalence of neuropsychiatric manifestations occurring in patients with systemic lupus erythematosus (NPSLE), according to American College Rheumatology standardized definitions for NPSLE, and evaluated relationship between NPSLE antiphospholipid antibodies. Sixty-one consecutive SLE were studied. Neuropsychiatric consistent diagnosis occurred 44 (72%). Patients showed significantly higher levels anticardiolipin
To study concentrations of adipokines in patients with systemic lupus erythematosus (SLE) and the relationship among adipokines, metabolic syndrome (MeS), cardiovascular disease (CVD) risk factors.We enrolled 50 SLE 26 controls, all women. Leptin, resistin, visfatin, adiponectin were measured by commercial ELISA kits.MeS prevalence was increased subjects SLE. Leptin levels higher than controls. Among patients, independent determinants leptin insulin (p < 0.0001), triglycerides = 0.03), body...
To investigate the thrombotic tendency in patients with systemic lupus erythematosus (SLE) by evaluating congenital or acquired abnormalities associated an increased risk of venous and/or arterial thrombosis.A total 57 SLE were included study. Twenty-one (37%) had a history thrombosis and 36 (63%) did not have such history. Sera from 50 healthy controls examined. Protein C, protein S, antithrombin, D-dimer, fibrinogen, homocysteine, anticardiolipin antibodies (aCL), anticoagulant (LAC),...
Detection of early carotid vascular disease in patients with systemic lupus erythematosus (SLE) is considered mandatory for evaluation subclinical atherosclerosis (ATS), and various ultrasonographic (US) parameters have been proposed. In the present investigation, 33 SLE healthy age-matched females studied by colour-coded sonography common artery, assessing intima-media thickness (IMT), strain (VS), distensibility (VD), stiffness (VSf) pressure-strain elastic modulus (PSEM) as possible...
Objectives: To assess the prevalence of interstitial lung disease (ILD) in patients with different forms connective tissue (CTD) using non‐invasive procedures including high‐resolution computed tomography (HRCT) and to evaluate relationship between imaging functional status patients.Methods: Eighty‐one subjects CTD (47 inpatients 34 outpatients) were evaluated pulmonary function tests (PFT) radiological investigations. The extent severity was quantified an HRCT scoring system previously used...
Alexithymia is conceptualized as a disorder of emotion regulation mechanisms, which involves dissociation emotional and physical responses to life events bodily sensations. Our results might suggest possible relationship between the alexithymic construct TNF levels in RA patients. These preliminary findings corroborate integrated bidirectional interactions neuropsychological mechanisms neuroendocrine-immune system patients affected by autoimmune diseases contribute finding common biological...
Objectives: BAFF and APRIL belong to the tumor necrosis factor (TNF) superfamily are crucial for survival, maturation, differentiation of B cells. Aim study is evaluate in patients affected by Sjögren syndrome (SS) systemic lupus erythematosus (SLE). Methods: Sixty patients, (40 SLE, 20 SS) healthy subjects were enrolled this study. All evaluated laboratory data (ESR, CRP, immunoglobulin G, A M, complement fragments C3 C4, LDH, beta2microglobulin, serum levels rheumatoid factor),...
Objective: Aim of this study was to evaluate the prevalence alexithymia in patients affected by SLE or RA and investigate correlation between immunoendocrine parameters (PRL, hGH, IL-6 TNF-alfa). Methods: Twenty-five (12 13 RA, respectively) were enrolled into study. The Toronto Alexithymia Scale-20 (TAS-20) administered. PRL, TNF-alfa levels measured commercially available ELISA kits. Results: (TAS-20≥51) 54% 42% patients. hGH serum 3.1±4.2 1.1±0.9 IU/ml respectively. PRL concentration...