Véronique Ramoni
- Systemic Lupus Erythematosus Research
- Pregnancy and Medication Impact
- Reproductive System and Pregnancy
- Systemic Sclerosis and Related Diseases
- Eosinophilic Esophagitis
- Platelet Disorders and Treatments
- Autoimmune and Inflammatory Disorders Research
- Endometriosis Research and Treatment
- Renal Diseases and Glomerulopathies
- Monoclonal and Polyclonal Antibodies Research
- Cardiovascular Issues in Pregnancy
- Eosinophilic Disorders and Syndromes
- Pregnancy and preeclampsia studies
- Rheumatoid Arthritis Research and Therapies
- Immunodeficiency and Autoimmune Disorders
- Autoimmune Bullous Skin Diseases
- Cell Adhesion Molecules Research
- Parvovirus B19 Infection Studies
- Connective tissue disorders research
- Blood disorders and treatments
- Lymphoma Diagnosis and Treatment
- Viral Infections and Immunology Research
- Cardiac Arrhythmias and Treatments
- Hemophilia Treatment and Research
- Urticaria and Related Conditions
Ospedale Maggiore di Lodi
2022-2024
Ospedale Maggiore
2022-2024
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2022-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2022
University of Pavia
2010-2022
Policlinico San Matteo Fondazione
2010-2022
Aziende Socio Sanitarie Territoriale Lodi
2021
Center for Rheumatology
2019
Pavia nel Cuore
2017-2018
Ospedale Papa Giovanni XXIII
2016-2018
To assess fetal and maternal outcomes in women with systemic sclerosis (SSc).Prospectively collected data on 99 SSc from 25 Italian centers were analyzed retrospectively. Women observed during 109 pregnancies (from 2000 to 2011), compared those the general obstetric population (total of 3,939 deliveries). The age at conception was a mean ± SD 31.8 5.3 years, median disease duration 60 months (range 2-193 months).SSc patients, population, had significantly increased frequency preterm...
Summary Previous thrombosis, diagnosis of systemic lupus erythematosus (SLE) and triple antiphospholipid (aPL) antibody positivity have recently been found to be independent factors associated pregnancy failure during conventional therapy in women with syndrome (APS). This study aimed assess the effect various treatment strategies on outcomes APS risk for failure. One hundred ninety-six pregnancies 156 patients diagnosed were analysed: 118 (60.2%) these had previous 81 (41.3%) SLE, 107...
Abstract The effect of additional treatments combined with conventional therapy on pregnancy outcomes was examined in high-risk primary antiphospholipid syndrome (PAPS) patients to identify the most effective treatment strategy. study's inclusion criteria were (1) positivity lupus anticoagulant alone or associated anticardiolipin and/or anti-β2 glycoprotein I antibodies; (2) a history severe maternal–foetal complications (Group I) one more pregnancies refractory leading unexplained foetal...
To investigate pregnancy outcomes in women with autoimmune rheumatic diseases (ARD) the Italian prospective cohort study P-RHEUM.it.
Objective: Neonatal Lupus (NL) is a rare syndrome caused by placental transfer of maternal anti-SSA/Ro and anti-La/SSB autoantibodies to the fetus. The rarity this condition requires establishment multidisciplinary registries in order improve our knowledge. Method: Inclusion criteria retrospective study were confirmed positivity for and/or anti-SSB/La antibodies, presence II or III degree congenital heart block (CHB) utero neonatal period (up 30 days after birth). Result: Eighty-nine cases...
Antiphospholipid syndrome (APS) is a rare disease characterised by venous and/or arterial thrombosis, pregnancy complications and the presence of specific autoantibodies called antiphospholipid antibodies. This review aims to identify existing clinical practice guidelines (CPG) as part ERN ReCONNET project, aimed at evaluating CPGs or recommendations in complex diseases. Seventeen papers providing important data were identified; however, literature search highlighted scarceness reliable...
The burden of pregnancy complications associated with well defined, already established systemic rheumatic diseases preexisting such as rheumatoid arthritis, lupus erythematosus or scleroderma is known. Systemic are characterized by a long natural history few symptoms, an undifferentiated picture remitting course making difficult timely diagnosis. It has been suggested that screening measures for these could be useful but the impact unrecognized disorders on outcome unknown. objective study...
The objective of this study was to evaluate the rates previously undiagnosed rheumatic diseases during first trimester pregnancy and their impact on outcome.Pregnant women in were screened using a two-step approach self-administered 10-item questionnaire subsequent testing for autoantibodies (antinuclear antibody, anti-double-stranded DNA, anti-extractable nuclear antigen, anticardiolipin antibodies, anti-β2-glycoprotein I antibodies lupus anticoagulant) evaluation by rheumatologist....
Objective. To evaluate the association between serum complement levels (C3 and C4) obstetric complications. Methods. Fifty-seven pregnancies in primary APS (PAPS) patients were compared with 49 UCTD SS. A group of 175 healthy pregnant women studied to calculate a normality range for C3 C4 during pregnancy. Such was applied define hypocomplementaemia PAPS UCTD/SS. Results. Both groups (PAPS UCTD/SS) showed significantly lower each trimester as women; conversely, no significant difference...
Objective. To study anti-Ro/La-negative congenital heart block (CHB). Methods. Forty-five fetuses with CHB were evaluated by analysis of anti-Ro/La antibodies using sensitive laboratory methods. Results. There 9 cases CHB; 3 died (33.3%). Only (33.3%) complete in utero and 5 (55.5%) unstable. No specific etiology was diagnosed. Six infants (66.6%) given pacemakers. 36 anti-Ro/La-positive CHB. All except 2 (94.4%) had atrioventricular utero. Ten (27.8%), one (2.7%) developed severe dilated...
The aim was to determine whether assisted reproductive technologies (ARTs) confer additional risk in rheumatic patients (in terms of disease flare and fetal–maternal complications) whether, if performed, their efficacy is affected by maternal disease. Sixty infertile women undergoing 111 ART cycles were included. Clinical pregnancy rate, live birth flares maternal–fetal complications recorded. One hundred eleven 60 analysed. We reported 46 pregnancies (41.4%), 3 (3.1%) cases ovarian...
Objective To evaluate the impact of preclinical systemic autoimmune rheumatic disorders on pregnancy outcome. Methods In this longitudinal cohort study, patients were enrolled during first trimester if they reported having had connective tissue disorder symptoms, found to be positive for circulating autoantibodies, and clinical evaluation judged have a or incomplete disorder. The incidence fetal growth restriction (FGR), preeclampsia, adverse outcomes in with was compared that selected...
Objective To evaluate the prevalence of undiagnosed rheumatic diseases in first trimester pregnancy. Design We screened for 1210 consecutive pregnant women during pregnancy using a 10‐item questionnaire. Setting A university hospital northern Italy. Population One hundred and thirty‐seven (11.3%) who answered positively to at least one question constituted cases were compared with 107 negative controls. Methods Cases controls tested autoantibodies (antinuclear antibody, anti‐double‐stranded...