A5077213592- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Rheumatoid Arthritis Research and Therapies
- Atherosclerosis and Cardiovascular Diseases
- Monoclonal and Polyclonal Antibodies Research
- Spondyloarthritis Studies and Treatments
- Liver Disease Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Platelet Disorders and Treatments
- T-cell and B-cell Immunology
- Peripheral Neuropathies and Disorders
- Immunodeficiency and Autoimmune Disorders
- Liver Disease and Transplantation
- Chronic Lymphocytic Leukemia Research
- Renal Diseases and Glomerulopathies
- Adipokines, Inflammation, and Metabolic Diseases
- Vasculitis and related conditions
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Eosinophilic Esophagitis
- Salivary Gland Disorders and Functions
- Urticaria and Related Conditions
- Hepatitis C virus research
- Dermatologic Treatments and Research
- Autoimmune Bullous Skin Diseases
Università Campus Bio-Medico
2013-2022
Campus Bio Medico University Hospital
2003-2022
Società Italiana di Reumatologia
2019
University of Campania "Luigi Vanvitelli"
2018
Center for Rheumatology
2005-2018
IRCCS Istituto Auxologico Italiano
2018
University of Palermo
2017
Sapienza University of Rome
1994-2010
Medico
2009
Weatherford College
2007
The authors assessed the prevalence of neuropsychiatric manifestations occurring in patients with systemic lupus erythematosus (NPSLE), according to American College Rheumatology standardized definitions for NPSLE, and evaluated relationship between NPSLE antiphospholipid antibodies. Sixty-one consecutive SLE were studied. Neuropsychiatric consistent diagnosis occurred 44 (72%). Patients showed significantly higher levels anticardiolipin
To study concentrations of adipokines in patients with systemic lupus erythematosus (SLE) and the relationship among adipokines, metabolic syndrome (MeS), cardiovascular disease (CVD) risk factors.We enrolled 50 SLE 26 controls, all women. Leptin, resistin, visfatin, adiponectin were measured by commercial ELISA kits.MeS prevalence was increased subjects SLE. Leptin levels higher than controls. Among patients, independent determinants leptin insulin (p < 0.0001), triglycerides = 0.03), body...
The diagnostic, predictive and prognostic role of anti-cyclic citrullinated peptide (CCP) antibodies in rheumatoid arthritis (RA) patients is widely accepted. Moreover, detection these subjects presenting with undifferentiated (UA) associated a significant risk to develop the disease. On other hand, clinical significance evaluating anti-CCP levels inflammatory at disease onset has not been fully clarified. goal this prospective study analyze value titer quantification UA subjects.Serial...
The aim of this study was to evaluate the proportion patients with Systemic Lupus Erythematosus (SLE) who did not met WHO recommendations for physical activity and amount time spent in sedentary behavior.SLE were consecutively enrolled a cross sectional study. type behavior evaluated using IPAQ short form questionnaire. adequate defined according 2010 health 2017 SBRN consensus. We also assessed quality life SF-36, mood disorders BDI HAM-H, fatigue Facit-Fatigue sleep PSQI scores.Physical...
Background Secukinumab (SEC) is effective for ankylosing spondylitis (AS) and psoriatic arthritis (PsA) in randomized trials, but real-life data are lacking.Research design methods Real-life, prospective observational study on 169 consecutive outpatients at baseline (T0) 6 (T6) 12 months (T12) after starting SEC (39 AS, 23%; 130 PsA, 77%).Results Significant improvement was seen T6 T12 all clinical variables, including TJC, SJC, ESR, CRP, DAPSA, ASDAS-CRP, BASDAI, as well patient-reported...
Abstract Objective . To evaluate the efficacy of long‐term treatment with cyclosporin A (CSA) in systemic lupus erythematosus (SLE). Methods Thirty patients SLE whose condition was either poorly responsive or unresponsive to steroids and/or cytotoxic drugs were enrolled a prospective, nonrandomized study CSA. Patients hypertension hypercreatinemia excluded. Disease activity evaluated according measure. Assessments made prior entry and after 6, 12, 18, 24 months. Results Twenty‐seven...
Abstract Background: The recommended method for antinuclear antibodies (ANA) detection is indirect immunofluorescence (IIF). To pursue a high image quality without artefacts and reduce interobserver variability, this study aims at evaluating the reliability of automatically acquired digital images IIF slides diagnostic purposes. Methods: Ninety‐six sera were screened ANA by on HEp‐2 cells. Two expert physicians looking both fluorescence microscope computer monitor performed blind to evaluate...
Rheumatoid arthritis (RA) is associated with an increased risk of morbidity and mortality, when compared general population, largely due to enhanced atherosclerotic disease. In this work, we aimed at assessing both occurrence predictive factors subclinical clinical atherosclerosis in RA. From January 1, 2015, December 31, consecutive participants RA, admitted Italian Rheumatology Units, were assessed the GIRRCS (Gruppo Italiano di Ricerca Reumatologia Clinica e Sperimentale) cohort. After...
Objectives Remission in systemic lupus erythematosus (SLE) is defined through a combination of ‘clinical SLE Disease Activity Index (cSLEDAI)=0’, ‘physician's global assessment (PGA) <0.5’ and ‘prednisone (PDN) ≤5 mg/day’. We investigated the performance these items, alone or combination, defining remission predicting SLICC/ACR Damage Index. Methods tested seven potential definitions patients followed-up for ≥5 years: PDN mg/day; PGA <0.5; cSLEDAI=0; <0.5 plus cSLEDAI=0 mg/day...
To investigate the thrombotic tendency in patients with systemic lupus erythematosus (SLE) by evaluating congenital or acquired abnormalities associated an increased risk of venous and/or arterial thrombosis.A total 57 SLE were included study. Twenty-one (37%) had a history thrombosis and 36 (63%) did not have such history. Sera from 50 healthy controls examined. Protein C, protein S, antithrombin, D-dimer, fibrinogen, homocysteine, anticardiolipin antibodies (aCL), anticoagulant (LAC),...