Umberto di Luzio Paparatti

ORCID: 0009-0002-1267-0696
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About
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Research Areas
  • Parathyroid Disorders and Treatments
  • Dialysis and Renal Disease Management
  • Psoriasis: Treatment and Pathogenesis
  • Vitamin D Research Studies
  • Respiratory viral infections research
  • Spondyloarthritis Studies and Treatments
  • Smoking Behavior and Cessation
  • Tracheal and airway disorders
  • Chronic Kidney Disease and Diabetes
  • Parkinson's Disease Mechanisms and Treatments
  • Rheumatoid Arthritis Research and Therapies
  • Pharmacological Effects and Toxicity Studies
  • Dermatology and Skin Diseases
  • Autoimmune and Inflammatory Disorders Research
  • Herpesvirus Infections and Treatments
  • Congenital Heart Disease Studies
  • Renal and Vascular Pathologies
  • HIV/AIDS drug development and treatment
  • Pneumonia and Respiratory Infections
  • Magnesium in Health and Disease
  • Neonatal Respiratory Health Research
  • HIV/AIDS Research and Interventions
  • Nasal Surgery and Airway Studies
  • Cardiovascular Conditions and Treatments
  • Immunodeficiency and Autoimmune Disorders

Philip Morris International (Switzerland)
2022-2024

ABB (Italy)
2013-2019

Marche Polytechnic University
2019

AbbVie (United States)
2014

AbbVie (Japan)
2014

University of Padua
2011

Abbott (Canada)
2006-2007

University of Pavia
1999

GlaxoSmithKline (Italy)
1999

Objective. The purpose of the ULISSE study was to evaluate prevalence clinical and ultrasonographic (US) entheseal involvement in patients with psoriatic arthritis (PsA), psoriasis, fibromyalgia syndrome (FMS). Methods. In this cross-sectional multicenter study, PsA psoriasis (not taking systemic therapy) FMS underwent a evaluation entheses, B-mode power Doppler examination 6 pairs entheses. Results. analyzed 140 PsA, 51 FMS. Clinical US examinations were performed 1960 1680 entheses group,...

10.3899/jrheum.171411 article EN The Journal of Rheumatology 2019-03-15

Variability in severity among different respiratory syncytial virus (RSV) seasons may influence hospital admission rates for RSV-induced lower tract infection (LRTI) young children. The aim of the present study was to identify through logistic regression analysis, risk factors associated with higher likelihood acquire LRTI, children symptoms severe enough lead admission. Over four consecutive RSV (2000-2004), records from <4 years age admitted LRTI ("cases") were compared those not due and...

10.1007/s00431-007-0418-y article EN cc-by-nc European Journal of Pediatrics 2007-02-16

Caring for a person with Parkinson's disease (PD) is associated an increased risk of psychiatric morbidity and persistent distress. The objective this study was to describe the burden related factors caregivers advanced PD (APD) patients either treated continuous dopaminergic delivery systems or standard therapy. This cross-sectional, epidemiologic conducted in 13 Italian sites enrolled delivering [either levodopa/carbidopa intestinal gel (LCIG) infusion subcutaneous apomorphine (CSAI)]...

10.1007/s00415-018-8816-9 article EN cc-by Journal of Neurology 2018-03-07

BackgroundChronic kidney disease (CKD) patients affected by mineral bone disorders (MBD) have higher rates of all-cause and cardiovascular-related mortality. Approximately, one-third dialysis low serum parathyroid hormone (PTH) levels (≤150 pg/mL). However, the reason why these mortality compared to with normal PTH has not yet been fully elucidated.

10.1093/ndt/gfs108 article EN Nephrology Dialysis Transplantation 2012-04-20

Abstract Background Psoriasis can have cumulative physical and psychosocial effects preventing sufferers from achieving their full‐life potential. Few studies addressed the impact of psoriasis on work‐related characteristics. Objective To evaluate education prospects work limitations in patients with moderate‐to‐severe psoriasis. Methods This study was conducted 29 dermatology centres across Italy. Information collected by questionnaire during office visits. Results A total 787 (64% male,...

10.1111/jdv.12233 article EN Journal of the European Academy of Dermatology and Venereology 2013-08-21

Vitamin D receptor activator (VDRA) therapy has been shown to be associated with reduced mortality rates in chronic kidney disease (CKD) patients secondary hyperparathyroidism (SHPT). However, differences between VDRAs their ability reduce both all-cause and cardiovascular-related are not yet fully elucidated.The objective of the current analysis was determine effect VDRA on an Italian dialysis population, observed prospectively every 6 months for 18 months. Patients were investigated risk...

10.1159/000325454 article EN Blood Purification 2011-01-01

The last decades have witnessed an increasing interest for the psychosocial aspects of chronic skin diseases, such as psoriasis. Nonetheless, systematic assessments impact psoriasis on patients' lives are rarely done in daily clinical practice. existing instruments mostly meant to be completed by patients alone, and comprise a graphical representation results.To develop questionnaire allowing both quick assessment and, at same time, intuitive graphic visualization outcome test.A preliminary...

10.1111/j.1468-3083.2011.04192.x article EN Journal of the European Academy of Dermatology and Venereology 2011-08-08

Several levodopa/carbidopa intestinal gel (LCIG) studies showed a significant reduction of OFF time and increase ON time, as well dyskinesia, improvement non-motor symptoms quality life. However, few have been conducted in large population for more than 3 years. Interim outcomes from GREENFIELD observational study on Italian cohort advanced PD patients who started LCIG routine care between 2007 2014, still treatment at the enrollment, are presented. Comparison baseline (before start) visit 1...

10.1007/s10072-016-2664-0 article EN cc-by Neurological Sciences 2016-07-15

Depression in HIV/AIDS patients affects adherence and disease progression often goes unnoticed. DHIVA is a cross-sectional epidemiologic survey, investigating the prevalence of depression people living with HIV through use validated self-administered scale (CES-D-20), as well degree concordance between physician's perception patients' reports. A total 690 HIV-infected attending 24 centers across Italy were enrolled. Concordance was calculated by K statistics. Association subject...

10.1080/09540121.2015.1080794 article EN cc-by-nc-nd AIDS Care 2015-10-13

Chronic kidney disease (CKD) is an important public health problem. Most of the evidence on its costs relates to patients receiving dialysis or transplants, which shows that, in these phases, CKD poses a high burden payers. Less available predialytic phase.The aim this study was estimate annual cost with not treatment, using Italian healthcare system perspective and prospective approach.A 3-year observational (December 2010-September 2014) carried out collect data resource consumption for...

10.1007/s41669-017-0062-z article EN cc-by-nc PharmacoEconomics - Open 2017-12-04

&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; Mineral Bone Disorders (MBD) is prevalent in hemodialysis (HD) patients and associated with increased cardiovascular mortality. The FARO-2 study evaluated the achievement of NKF/K-DOQI guidelines on recommended target values for serum calcium (Ca), phosphorous (P) intact parathyroid hormone (PTH) levels survival incident HD patients. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; Data were collected by questionnaire from 568 followed...

10.1159/000365386 article EN Blood Purification 2014-01-01

Abstract Background The Psodisk is a 10‐item visual instrument, aimed at measuring the burden of psoriasis on patients. Objectives To validate in large sample patients with psoriasis, and to define categories for interpretation scores. Methods Data were collected 21 dermatological centres. was administered baseline (t0), after 2 or 3 days (t1) about months (t2) baseline, data used assess validity reliability instrument. cut‐off scores determined using perception severity disease by patient...

10.1111/jdv.12668 article EN Journal of the European Academy of Dermatology and Venereology 2014-09-17

Objective To compare the effect of two dose regimens zidovudine in treatment severe HIV-related thrombocytopenia (TP). Design: Eighty-four patients with TP and platelet counts < 50 x 109/I were enrolled an open study at six centres. Patients randomized into groups to receive (group A, 500 mg per day; group B, 1000 day) for 6 months. Methods Platelet determined monthly categorized as complete responders (CR; platelets > 100 109/I), partial (PR; or failures (F; 109/I). CD4+ CD8 + lymphocytes,...

10.1097/00002030-199302000-00008 article EN AIDS 1993-02-01

Mortality rate among patients with stage five chronic kidney disease (CKD) maintained on hemodialysis (HD) is high. Although evidence suggests that use of Vitamin D Receptor Activators (VDRA) in CKD increases survival, few studies have examined the effect VDRA incident HD patients. The FARO-2 study evaluated clinical outcome therapy mortality was a longitudinal epidemiological performed 568 followed prospectively from 26 dialysis centers over 3-year period. Data were collected every 6 months...

10.1186/s12882-015-0006-8 article EN cc-by BMC Nephrology 2015-02-05

Due to different social and epidemiological factors, the eligibility criteria receive palivizumab prophylaxis may be between countries, especially in "otherwise healthy" late preterm infants. We analyzed an Italian database of young children referred emergency departments for acute lower respiratory tract infection (ALRI) during RSV season over a four year period, when use as disease was not widespread premature The demographic environmental characteristics positivity (RSV+) hospitalized...

10.1186/s13052-016-0252-9 article EN cc-by ˜The œItalian Journal of Pediatrics/Italian journal of pediatrics 2016-04-25

In Italy, few studies have examined the clinical management of peritoneal dialysis (PD) patients, resulting in a lack information and awareness. A total 378 PD patients (64.7 ± 14.3 years, 58.9% males) were enrolled across 15 centres 12-month retrospective 6-month prospective study. The primary objective was to evaluate achievement Kidney Disease Outcomes Quality Initiative Improving Global guidelines on recommended target values for anaemia, high blood pressure mineral metabolism....

10.1093/ckj/sfx092 article EN cc-by-nc Clinical Kidney Journal 2017-07-20

Background and objectives:Secondary hyperparathyroidism (SHPT) is a frequent complication of CKD with incidence, prevalence, costs increasing worldwide. The objective this analysis was to estimate therapy cost SHPT in sub-population the FARO study.Materials Methods:In study, an observational survey aimed evaluate patterns treatment patients who had undergone hemodialysis, pharmacological treatments biochemical parameters evolution data were collected four surveys. Patients maintaining same...

10.3111/13696998.2012.703632 article EN Journal of Medical Economics 2012-06-18
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