A5008638745- Nutrition and Health in Aging
- Diet and metabolism studies
- Body Composition Measurement Techniques
- Clinical Nutrition and Gastroenterology
- Eating Disorders and Behaviors
- Nutritional Studies and Diet
- Adipose Tissue and Metabolism
- Obesity, Physical Activity, Diet
- Inflammatory Bowel Disease
- Child Nutrition and Feeding Issues
- Blood Pressure and Hypertension Studies
- Cardiovascular Disease and Adiposity
- Liver Disease Diagnosis and Treatment
- Muscle metabolism and nutrition
- Obesity and Health Practices
- Adipokines, Inflammation, and Metabolic Diseases
- Diet, Metabolism, and Disease
- Bariatric Surgery and Outcomes
- Thermoregulation and physiological responses
- Heart Rate Variability and Autonomic Control
- Regulation of Appetite and Obesity
- Eosinophilic Esophagitis
- Hormonal Regulation and Hypertension
- Dialysis and Renal Disease Management
- Microscopic Colitis
Federico II University Hospital
2016-2025
University of Naples Federico II
2013-2025
University of Campania "Luigi Vanvitelli"
2023
University of Bari Aldo Moro
2022
National Agency for New Technologies, Energy and Sustainable Economic Development
2008-2021
Sapienza University of Rome
2019
Stazione Sperimentale per l'Industria delle Pelli e delle Materie Concianti
2017
Unité de Nutrition Humaine
2013
ENEA Portici Research Centre
2009
Indiana University School of Medicine
2007
Background Nonalcoholic fatty liver disease describes a set of conditions that range from to nonalcoholic steatohepatitis (NASH), and is considered the hepatic manifestation metabolic syndrome. Obesity insulin resistance are strongly associated with systemic markers inflammation. Objective Focusing on this aspect, we have attempted find noninvasive method could likely assess presence NASH help decide biopsy performance. Methods Using histology as gold standard diagnose disease, consecutively...
The aim of this study is to show that the differences among eating behaviours are related emotional dysregulation connected mental dimensions being part obese psychopathology. Eating can be considered a diagnostic feature at initial screening for determining obesity treatment: nutritional or bariatric surgery.1828 Obese subjects underwent psychiatric assessment before entering treatment surgery following multidisciplinary programme. 1121 were selected and enrolled in study: 850 inpatients...
Abstract Background Amino acid metabolism is dysregulated in colorectal cancer patients; however, it not clear whether pre-diagnostic levels of amino acids are associated with subsequent risk cancer. We investigated circulating relation to the European Prospective Investigation into Cancer and Nutrition (EPIC) UK Biobank cohorts. Methods Concentrations 13-21 were determined baseline fasting plasma or serum samples 654 incident cases matched controls EPIC. following adjustment for false...
Long-term therapy with antihypertensive agents that reduce sympathetic nervous system activity has been demonstrated by echocardiographic measurements to reverse left ventricular hypertrophy. This investigation evaluated the effects of salt depletion obtained both chlorthalidone (25 mg/day) and severe restriction intake (about 1016 mg Na+/day) on mass (LVM) in as short a time 12 weeks. Before study, patients had off medication balanced diet without for at least 2 weeks; they were then...
Significance Both evolutionarily and functionally, wakefulness requires, is accompanied by, food search intake for survival. From the molecular perspective, neuropeptide orexin-A (OX-A) promotes wakefulness, α–melanocyte-stimulating hormone (α-MSH) satiety, endocannabinoid 2-arachidonoylglycerol (2-AG) appetite. In cerebrospinal fluid of obese mice in plasma human subjects, we found an inverse correlation between OX-A α-MSH levels, which led us to uncover role promoting hyperphagia by...
The present study shows low circulating levels of SIRT4 in obese patients with nonalcoholic fatty liver disease mirroring its reduced mitochondrial expression an attempt to increase the fat oxidative capacity and then function muscle. modulates metabolism free acids reducing their high but, unfortunately, increasing ROS production. Great concentration acids, released by adipose tissue, coupled stress, directly results endothelial dysfunction, early atherosclerosis, coronary artery risk factor.
Obesity is a leading risk factor for metabolic syndrome whose further expression non-alcoholic fatty liver disease. Metabolic associated with proinflammatory state that contributes to insulin resistance. Finally, "metabolically benign obesity" not accompanied by resistance has recently been postulated exist.To find whether any inflammation markers were independently the presence of resistance, evaluating specific anthropometric, ultrasonographic and laboratory parameters in population young...
Inside the spectrum of non-alcoholic fatty liver disease, simple is generally thought as being "non progressive", differently from steatohepatitis, which increases in severity due to presence apoptosis/inflammation and fibrosis. The "benignity" widely accepted but conceptually difficult maintain because mechanisms underlying this entity are same ones that determine more severe form.Findings provide evidence iron overload associated with increased damage collagen deposition. Transforming...
"At-risk" severely obese subjects are characterized by insulin resistance, and higher visceral fat plasma lipid levels compared with metabolically healthy (MHO) subjects, although both groups have a high BMI mass. The aim of this study was to measure several serum adipokines gastrointestinal hormones in young population from Southern Italy identify biochemical markers the "at-risk" insulin-resistant profile. We studied 160 unrelated white adults (mean age = 25.2 years, mean 44.9 kg/m(2), 65%...
The aim of this study was to evaluate the efficacy a nutritional program, which is characterized by different modulation proteins, in adult patients with sarcopenic obesity.We studied 18 obese women aged 41-74 years. Obesity diagnosed as fat mass > 34.8% and sarcopenia defined when lean body <90% subject's ideal free mass. All subjects were randomly assigned interventions: Hypocaloric diet plus placebo (A) hypocaloric high-protein (1.2-1.4 g / kg weight reference day) (B). Anthropometric...