A5030413815- Treatment of Major Depression
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health Research Topics
- Mental Health Treatment and Access
- Posttraumatic Stress Disorder Research
- Family and Patient Care in Intensive Care Units
- Intensive Care Unit Cognitive Disorders
- Vagus Nerve Stimulation Research
- Digital Mental Health Interventions
- Heart Rate Variability and Autonomic Control
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare professionals’ stress and burnout
- EEG and Brain-Computer Interfaces
- Air Quality Monitoring and Forecasting
- Psychosomatic Disorders and Their Treatments
- Face Recognition and Perception
- Emotion and Mood Recognition
- Sleep and Work-Related Fatigue
- Stress Responses and Cortisol
- Cardiac Health and Mental Health
- COVID-19 and Mental Health
- Resilience and Mental Health
Ruhr University Bochum
2023
HR Wallingford
2023
Antidepressants must be taken for weeks before response can assessed with many patients not responding to the first medication prescribed. This often results in long delays effective treatment is started. induce changes processing of emotional stimuli early course treatment. In current study we whether and subjective symptoms over week antidepressant predicted clinical after 4-8 Such a predictive test may shorten time initiate depressed patients. Seventy-four primary care completed measures...
Depressed patients often do not respond to the first antidepressant prescribed, resulting in sequential trials of different medications. Personalised medicine offers a means reducing this delay; however, clinical effectiveness personalised approaches treatment has previously been tested. We assessed using predictive algorithm, based on behavioural tests affective cognition and subjective symptoms, guide treatment. conducted multicentre, open-label, randomised controlled trial 913...
Abstract Intrusive memories (IMs) after traumatic events can be distressing and disrupt mental health functioning. We evaluated the impact of a brief remotely-delivered digital imagery-competing task intervention on number IMs for intensive care unit (ICU) staff who faced repeated trauma exposure during COVID-19 pandemic using two-arm, parallel-group, single-blind randomised controlled trial, with comparator arm receiving delayed access to active treatment (crossover). Eligible participants...
Abstract Intensive care unit (ICU) staff continue to face recurrent work-related traumatic events throughout the COVID-19 pandemic. Intrusive memories (IMs) of such comprise sensory image-based memories. Harnessing research on preventing IMs with a novel behavioural intervention day trauma, here we take critical next steps in developing this approach as treatment for ICU who are already experiencing days, weeks, or months post-trauma. To address urgent need develop mental health...
<title>Abstract</title> Major Depressive Disorder can be conceptualized as a chronic stress condition associated with autonomic dysregulation, including blunted heart rate reactivity, changes in cortisol levels and peripheral inflammation, pointing to sympathetic activation parasympathetic withdrawal. Transcutaneous vagus nerve Stimulation (taVNS) offers non-invasive method stimulate the – key component of system restore balance. Here, we examined whether emotional, cardiac, inflammatory...
<sec> <title>BACKGROUND</title> Barriers to accessing mental health support are common experiences reported by university students. Digital tools can improve equitable access the indicated level of and provide actionable insight recommendations. </sec> <title>OBJECTIVE</title> This study aimed evaluate acceptability effectiveness a web-based self-guided well-being platform (U-Flourish Platform) that was tailored specifically for <title>METHODS</title> The i-spero® adapted in partnership with...
Antidepressant medication is commonly used to treat depression. However, many patients do not respond the first prescribed and improvements in symptoms are generally only detectable by clinicians 4–6 weeks after has been initiated. As a result, there often long delay between decision initiate an antidepressant identification of effective treatment regimen. Previous work demonstrated that medications alter subtle measures affective cognition depressed patients, such as appraisal facial...
Abstract Aim To assess the acceptability and explore utility of a novel digital platform designed as student‐facing well‐being mental health support. Methods An adapted version i‐spero® was piloted support part routine university‐based care. In both pathways, student participants completed baseline demographics brief validated measures health. Weekly anxiety (GAD‐7) depression (PHQ‐9) Week 8 Experience Survey were also scheduled. Integrated mixed methods analysis used to these platforms....
Abstract Background Only a relatively low proportion of university students seek help for anxiety and depression disorders, partly because they dislike current drug psychological treatment options would prefer home-based care. The aim this study is to determine the feasibility, acceptability cost utility Alpha-Stim cranial electrostimulation (CES) delivered through nurse led primary care clinic as daily symptoms by student at home in contrast usual Method Feasibility offering CES terms take...
Background A RCT of a novel intervention to detect antidepressant medication response (the PReDicT Test) took place in five European countries, accompanied by anested study its acceptability and implementation presented here. The results indicated no effect the on depression at 8 weeks (primary outcome), although effects anxiety functioning 24 were found.Methods nested used mixed methods. aim was explore patient experiences Test including implementation, inform use within care. bespoke...
ABSTRACT Intensive care unit (ICU) staff continue to face recurrent work-related traumatic events throughout the COVID-19 pandemic. Intrusive memories (IMs) of such comprise sensory image-based memories. Harnessing research on preventing IMs with a novel behavioural intervention day trauma, here we take critical next steps in developing this approach as treatment for ICU who are already experiencing days, weeks, or months post-trauma. To address urgent need develop mental health...
Background Many intensive care unit (ICU) staff experience intrusive memories following work-related traumatic events, which can lead to long-term mental health outcomes and impact work functioning. There is a need for interventions that target in this population; however, factors such as stigma difficulty fitting into busy schedules pose barriers. The Brief Gameplay Intervention For National Health Service Intensive Care Unit Staff Affected By COVID-19 Trauma (GAINS) study tested brief,...
Depressed patients often focus on negative life events. Effective antidepressant therapy reverses this emotional bias (NEB) within 1 week. Clinical therapeutic effect usually requires 4-6 weeks. The value of implementing NEB monitoring for the personalisation is unknown. To estimate likely outcome and cost consequences adopting P1vital Oxford Emotional Test Battery (ETB) purpose in routine primary care England. A hybrid decision analytic model (decision tree plus Markov model) was developed...
Negative bias in facial emotion recognition is a well-established concept mental disorders such as depression. However, existing face sets of tests may be limited use international research, which could benefit from more contemporary and diverse alternatives. Here, we developed provide initial validation for the P1vital® Affective Faces set (PAFs) alternative to widely-used Pictures Facial Affect (PoFA).The PAFs was constructed 133 color photographs expressions ethnically-diverse trained...
<sec> <title>BACKGROUND</title> Many intensive care unit (ICU) staff experience intrusive memories following work-related traumatic events, which can lead to long-term mental health outcomes and impact work functioning. There is a need for interventions that target in this population; however, factors such as stigma difficulty fitting into busy schedules pose barriers. The Brief Gameplay Intervention For National Health Service Intensive Care Unit Staff Affected By COVID-19 Trauma (GAINS)...
Background: Major depressive disorder (MDD) is a highly prevalent psychiatric condition associated with significant disability, mortality and economic burden. A large proportion of MDD patients are treated in primary health care the local community. Attentional Bias Modification (ABM) training combination antidepressants could be an effective treatment. Here we test hypothesis that adding ABM procedure to regular treatment will result further improvement symptoms compared alone (treatment as...