Hu Zhangxue

ORCID: 0000-0003-1745-6293
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About
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Research Areas
  • Neonatal Respiratory Health Research
  • Neuroscience of respiration and sleep
  • Neonatal Health and Biochemistry
  • Neonatal and fetal brain pathology
  • Cancer Research and Treatments
  • Respiratory Support and Mechanisms
  • Toxoplasma gondii Research Studies
  • Autophagy in Disease and Therapy
  • Fatty Acid Research and Health
  • Kawasaki Disease and Coronary Complications
  • Vasculitis and related conditions
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Calcium signaling and nucleotide metabolism
  • Cell Adhesion Molecules Research
  • Systemic Lupus Erythematosus Research
  • Immunotherapy and Immune Responses
  • Pediatric Hepatobiliary Diseases and Treatments

Army Medical University
2010-2023

Daping Hospital
2010-2018

Abstract Coxsackievirus B3 (CVB3) is an important human pathogen linked to cardiac arrhythmias and acute heart failure. CVB3 infection has been reported induce the formation of autophagosomes that support viral replication in host cells. Interestingly, our study shows accumulation during caused by a blockage autophagosome–lysosome fusion rather than induction autophagosome biogenesis. Moreover, decreases transcription translation syntaxin 17 (STX17), SNARE (soluble N...

10.1038/s41419-018-0271-0 article EN cc-by Cell Death and Disease 2018-02-14

Abstract Increasing evidence has demonstrated that lung fluid absorption disorders might be an important cause of neonatal respiratory distress syndrome (RDS) by influencing gas exchange or surfactant function. The SCNN1A gene, which encodes the α-ENaC, predispose infants to RDS. To explore whether single-nucleotide polymorphisms (SNPs) are associated with RDS, we conducted a case-control study investigate RDS-associated loci in Han Chinese infants. Seven target SNPs were selected from gene...

10.1038/srep17317 article EN cc-by Scientific Reports 2015-11-27

It has been reported that the complete heart block (CHB) in neonatal lupus (NL) cannot be reversed. This study a case of NL-CHB was reversed by transcutaneous pacing and repeated plasmapheresis.A 35+ 6-week male preterm baby transferred to intensive care unit Army Medical Center May 2020 for slight cyanosis around lips nose. Two days after birth, sudden decrease rate observed during electrocardiogram (EGG) monitoring. Physical examination revealed bluish-purple discoloration an irregular...

10.1186/s12969-023-00920-w article EN cc-by Pediatric Rheumatology 2023-11-09
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