A5103135359- Extracellular vesicles in disease
- Ocular Diseases and Behçet’s Syndrome
- Corneal Surgery and Treatments
- interferon and immune responses
- Ocular Oncology and Treatments
- Retinal and Optic Conditions
- Immunotherapy and Immune Responses
- Inflammasome and immune disorders
- IgG4-Related and Inflammatory Diseases
Affiliated Eye Hospital of Wenzhou Medical College
2024
Wenzhou Medical University
2024
Tianjin Medical University
2024
Tianjin Medical University Eye Hospital
2024
The pathogenesis of thyroid-associated orbitopathy (TAO) remains incompletely understand. interaction between immunocytes and orbital fibroblasts (OFs) play a critical role in inflammatory fibrosis. Accumulating reports indicate that significant portion plasma exosomes (Pla-Exos) are derived from immune cells; however, their impact upon OFs function is unclear.
Abstract Glaucoma is the leading cause of irreversible blindness and characterized by progressive retinal ganglion cell (RGC) loss nerve fiber layer thinning. Currently, no existing treatment effective for preservation RGCs. MicroRNA-22-3p (miR22) small extracellular vesicles derived from mesenchymal stem cells (MSC-sEVs) have neuroprotective effects. In this study, we apply miR22-overexpressing MSC-sEVs in an N-methyl-D-aspartic acid (NMDA)-induced RGC injury model to assess their...
<title>Abstract</title> Glaucoma is the leading cause of irreversible blindness and characterized by progressive retinal ganglion cell (RGC) loss nerve fiber layer thinning. Currently, no existing treatment effective for preservation RGCs. MicroRNA-22-3p (miR22) exosomes derived from mesenchymal stem cells (MSC-Exos) have neuroprotective effects. In this study, we applied miR22-overexpressing MSC-Exos in an N-methyl-D-aspartic acid (NMDA)-induced RGC injury model to assess their therapeutic...