A5102004089- Metal-Organic Frameworks: Synthesis and Applications
- Covalent Organic Framework Applications
- Advanced Fluorescence Microscopy Techniques
- Cell Image Analysis Techniques
- Advanced Biosensing Techniques and Applications
- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- Phase Change Materials Research
- Glaucoma and retinal disorders
- Virus-based gene therapy research
- Adsorption and Cooling Systems
- Cyclopropane Reaction Mechanisms
- Risk Perception and Management
- Circadian rhythm and melatonin
- Disaster Management and Resilience
- Regulation of Appetite and Obesity
- Catalytic Alkyne Reactions
- Neuroendocrine regulation and behavior
- Immune cells in cancer
- Graphite, nuclear technology, radiation studies
- Occupational Health and Safety in Workplaces
- SARS-CoV-2 detection and testing
- Membrane Separation and Gas Transport
- Studies on Chitinases and Chitosanases
- Calcium signaling and nucleotide metabolism
Duke University
2008-2025
Zhejiang University
2014-2024
University of Arizona
2023-2024
Durham Technical Community College
2021-2024
Nanjing University
2021-2023
Second Affiliated Hospital of Zhejiang University
2022-2023
Zhejiang Lab
2023
University Medical Center
2023
Despite lipid nanoparticles' (LNPs) success in the effective and safe delivery of mRNA vaccines, an inhalation-based therapy for lung diseases remains challenging. LNPs tend to disintegrate due shear stress during aerosolization, leading ineffective delivery. Therefore, need remain stable through process nebulization mucus penetration, yet labile enough endosomal escape. To meet these opposing needs, we utilized PEG enhance surficial stability with inclusion a cholesterol analog,...
The establishment of highly permanent porosity in hydrogen-bonded organic frameworks (HOFs) is a long-standing challenge due to the fragile nature hydrogen bonds, which delimits their broad applications gas separation. Herein, we report novel diamondoid HOF (termed as ZJU-HOF-10) and utilize supercritical carbon dioxide (sc-CO2) drying method significantly improve its for boosting ethane/ethylene (C2H6/C2H4) Compared with commonly used heat/vacuum activation, sc-CO2 activated ZJU-HOF-10(sc)...
Metal–organic framework (MOF) thin films with flexible nature and prominent qualities have opened doors to new technological applications in different fields. Herein, we propose an electrochemical biosensor for the dual detection of Staphylococcus aureus based on electrodeposition Cu metal–organic (Cu-MOF) films. The promising sensing layer features good electronic conductivity enhanced electron-transfer property can not only identify S. through specific micrococcal nucleases supernatant but...
We designed and realized a water-stable AIE-active HOF (HOF-TPE-CN) with notably enhanced fluorescence emission for achieving highly sensitive selective sensing of mono-nitrophenols in water.
An electrochemical biosensor is fabricated to identify the phenotype of aggressive breast cancer cells via detection HER-2 together with MMP-2.
A viral infection process covers a large range of spatiotemporal scales. Tracking the with fluorescent labels over long durations while maintaining fast sampling rate requires bright and highly photostable labels. StayGold is recently identified green protein that has greater photostability higher signal intensity under identical illumination conditions compared to existing fluorescence variants. Here, fusions were used generate virus-like particles (StayGold-VLPs) achieve hour-long 3D...
ABSTRACT Nanoparticle diffusion in 3D porous structures is critical to understanding natural and synthetic systems but remains underexplored due limitations traditional microscopy methods. Here, we use Single-Molecule Active-feedback Real-time Tracking (3D-SMART) resolve nanoparticle dynamics agarose gels with unprecedented spatiotemporal resolution. We highlight ‘hopping diffusion’, where particles intermittently escape confinement pockets, providing insights into hydrogel microstructure....
Defensive behaviors are critical for animal’s survival. Both the paraventricular nucleus of hypothalamus (PVN) and parabrachial (PBN) have been shown to be involved in defensive behaviors. However, whether there direct connections between them mediate remains unclear. Here, by retrograde anterograde tracing, we uncover that cholecystokinin (CCK)-expressing neurons lateral PBN (LPB CCK ) directly project PVN. By vivo fiber photometry recording, find LPB actively respond various threat...
Abstract Skeletal reorganization is a type of intriguing processes because their interesting mechanism, high atom-economy and synthetic versatility. Herein, we describe an unusual, divergent skeletal N -sulfonyl ynamides. Upon treatment with lithium diisopropylamine (LDA), ynamides undergo to deliver thiete sulfones, while the additional use 1,3-dimethyl-tetrahydropyrimidin-2(1 H )-one (DMPU) shifts process furnish propargyl sulfonamides. This divergence features broad substrate scope...
We herein successfully realized the first example of using a stable HOF (ZJU-HOF-1) for highly efficient removal both trace (1%) and bulk (50%) CO 2 from /CO mixtures under dry humid conditions.
We propose a unified structured light, consisting of an LED array and LCD mask, for high-quality acquisition both shape reflectance from single view. For geometry, one projects set learned mask patterns to accurately encode spatial information; the decoded results multiple LEDs are then aggregated produce final depth map. appearance, light cast through transparent efficiently probe angularly-varying reflectance. Per-point BRDF parameters differentiably optimized with respect corresponding...
Covalent organic frameworks (COFs) are gaining growing interest owing to their various structures and versatility. Since specific physical–chemical characteristics endow them great usage potentiality in biosensing, we herein have synthesized spherical COFs with regular shape good dispersion, which further used for the design of a novel nanoprobe by modifying Histostar on surface COFs. Moreover, applied fabrication an electrochemical biosensor detect exosomes. is special polymer, conjugated...
The viral infection process covers a large range of spatiotemporal scales. Tracking the with fluorescent labels over long durations while maintaining fast sampling rate requires bright and highly photostable labels. StayGold is recently identified green protein that has greater photostability higher signal intensity under identical illumination conditions as compared to existing fluorescence variants. Here, fusions were used generate virus-like particles (StayGold-VLPs) achieve hour-long 3D...
A novel electron-rich alkynyl-functionalized HOF material was designed and synthesized for efficient C 2 H 6 /C 4 separation. The alkynyl groups serve as functional binding sites to result in high adsorption capacity selectivity.