A5091674986- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Shoulder Injury and Treatment
- Anesthesia and Pain Management
- Knee injuries and reconstruction techniques
- Tendon Structure and Treatment
- Sarcoma Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Hip and Femur Fractures
- Dupuytren's Contracture and Treatments
- Blood transfusion and management
- Lower Extremity Biomechanics and Pathologies
- Blood Coagulation and Thrombosis Mechanisms
- Molecular Biology Techniques and Applications
- Elbow and Forearm Trauma Treatment
- Synthesis and Biological Activity
- Periodontal Regeneration and Treatments
- Orthopedic Surgery and Rehabilitation
- Cardiovascular Disease and Adiposity
- Protease and Inhibitor Mechanisms
- thermodynamics and calorimetric analyses
- Forensic and Genetic Research
- Pelvic and Acetabular Injuries
- Bone and Joint Diseases
Mayo Clinic
2020-2025
Mayo Clinic in Arizona
2020-2024
WinnMed
2020-2024
Mayo Clinic in Florida
2020
Aims Contemporary outcomes of total femoral arthroplasties (TFAs) in the non-oncological setting are limited. This study aimed to assess implant survival free from revision and reoperation, clinical outcomes, radiological results associated with TFAs for conditions. Methods We identified 24 patients who received between 1 January 2007 31 December 2021 through our institutional joint registry. The patients’ mean age was 66 years (48 83), BMI 33 kg/m 2 (21 54), median follow-up four (IQR 5)....
The specific advantages of spinal anesthesia compared with general for primary total hip arthroplasty (THA) remains unknown. Therefore, this study aimed to investigate the pain control, length stay, and postoperative outcomes associated in a large cohort THAs from single, high-volume academic institution.We retrospectively identified 13,730 (11,319 patients) 2001 2016 using our joint registry. Of these cases, 58% had 42% anesthesia. demographic characteristics were similar between groups,...
Spinal anaesthesia has seen increased use in contemporary primary total knee arthroplasties (TKAs). However, controversy exists about the benefits of spinal comparison to general TKAs. This study aimed investigate pain control, length stay (LOS), and complications associated with versus TKAs from a single, high-volume academic centre.We retrospectively identified 17,690 (13,297 patients) 2001 2016 using our institutional joint registry, where 52% had 48% anaesthesia. Baseline characteristics...
To evaluate tranexamic acid (TXA) when administered immediately on hospital presentation in patients with extracapsular peritrochanteric hip fractures to determine its effect (1) transfusion rates, (2) estimated blood loss, and (3) complications.
Experimental analyses of posttraumatic knee arthrofibrosis utilize a rabbit model as gold standard. However, rodent offers many advantages including reduced cost and comparison with other models organ fibrosis. This study aimed to characterize the biomechanical, histological, molecular features novel in rats. Forty eight rats were divided into two equal groups. An immobilization procedure was performed on right hind limbs experimental One group immobilized for 4 weeks 8 weeks. Both groups...
Aims As has been shown in larger animal models, knee immobilization can lead to arthrofibrotic phenotypes. Our study included 168 C57BL/6J female mice, with 24 serving as controls, and 144 undergoing a procedure induce contracture without osteoarthritis (OA). Methods Experimental knees were immobilized for either four weeks (72 mice) or eight mice), followed by remobilization period of zero (24 two after suture removal. Half the experimental also received an intra-articular injury....
Abstract Arthrofibrosis, which causes joint motion restrictions, is a common complication following total knee arthroplasty (TKA). Key features associated with arthrofibrosis include myofibroblast activation, stiffness, and excessive scar tissue formation. We previously demonstrated that adiponectin levels are suppressed within the tissues of patients affected by showed AdipoRon, an receptor agonist, exhibited anti‐fibrotic properties in human mesenchymal stem cells. In this study,...
Aims Orthopaedic and reconstructive surgeons are faced with large defects after the resection of malignant tumours sacrum. Spinopelvic reconstruction is advocated for resections above level S1 neural foramina or involving sacroiliac joint. Fixation may be augmented either free vascularized fibular flaps (FVFs) allograft struts (AFSs) in a cathedral style. However, there no studies comparing these techniques. Methods We reviewed 44 patients (23 female, 21 male) mean age 40 years (SD 17), who...
Abstract Arthrofibrosis is characterized by excessive extracellular matrix (ECM) deposition that results in restricted joint motion after total knee arthroplasties (TKAs). Currently, treatment options are limited. Therefore, an vitro model of knee‐related myofibroblastogenesis valuable to facilitate investigation the arthrofibrotic process, diagnostic and therapeutic options. In this study, we obtained intraoperative posterior capsule (PC), quadriceps tendon (QT), suprapatellar pouch (SP)...
(1) Background: Arthrofibrosis is a common cause of patient debility and dissatisfaction after total knee arthroplasty (TKA). The diversity molecular pathways involved in arthrofibrosis disease progression suggest that effective treatments for may require multimodal approach to counter the complex cellular mechanisms direct pathogenesis. In this study, we leveraged RNA-seq data define genes are suppressed patients identified adiponectin (ADIPOQ) as potential candidate. We hypothesized...
Abstract Introduction Advances in the care of cancer patients have resulted increased survival. The proximal femur is a common site for metastatic disease, often requiring surgical intervention. Tranexamic acid (TXA) has proven to be safe elective and traumatic femoral hemiarthroplasty; however, its use not been investigated oncologic patients. Method We reviewed 66 (37 males) with mean age 64 ± 3 years undergoing hemiarthroplasty disease neck. A total 22 (33%) received intraoperative TXA....
Objectives: To describe a reproducible technique for reduction assessment and percutaneous of unstable intertrochanteric fractures treated with cephalomedullary nail on traction table. Design: Retrospective cohort study. Setting: Level-1 trauma center. Patients: Two-hundred 20 consecutive patients fractures. Intervention: Initial closed performed Accessory incisions were used to facilitate in 77 (35%). All stabilized nail. Main Outcome Measurements: Radiographic outcome including union,...
Internal fixation of patella fractures remains technically challenging. Cannulated screws with an anterior tension band have been associated high rates implant prominence, and fracture comminution can make appropriate application a impractical. We present the results novel technique using transtendinous/transligamentous mini-fragment plate positioned peripherally around radially directed screws: termed wagon-wheel (WW) construct. Compared cohort treated cannulated band, there was no...
Intramedullary nail (IMN) fixation has become a treatment mean for impending and pathologic femur fractures. Currently there continues to be lack of data examining functional outcomes, complications, survivorship patients treated with IMNs metastatic disease the femur.We retrospectively identified 183 placed (n=145) or (n=38) fractures from 2010 2018. Functional outcomes complications including blood transfusions, venous thromboembolisms (VTEs) reoperations were studied.Patients lesions more...