Aleksandra Kezić

ORCID: 0000-0003-1790-7955
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About
Contact & Profiles
Research Areas
  • Organ Transplantation Techniques and Outcomes
  • Dialysis and Renal Disease Management
  • Stress Responses and Cortisol
  • Liver Disease and Transplantation
  • Cardiac Ischemia and Reperfusion
  • Chronic Kidney Disease and Diabetes
  • Immune Response and Inflammation
  • Iron Metabolism and Disorders
  • Renal Diseases and Glomerulopathies
  • Renal Transplantation Outcomes and Treatments
  • Drug-Induced Hepatotoxicity and Protection
  • Liver Disease Diagnosis and Treatment
  • Central Venous Catheters and Hemodialysis
  • Pregnancy and preeclampsia studies
  • Pancreatic function and diabetes
  • Adenosine and Purinergic Signaling
  • Electrolyte and hormonal disorders
  • Renal and Vascular Pathologies
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Erythropoietin and Anemia Treatment
  • Heme Oxygenase-1 and Carbon Monoxide
  • Spaceflight effects on biology
  • COVID-19 epidemiological studies
  • Exercise and Physiological Responses
  • Muscle and Compartmental Disorders

University of Belgrade
2013-2025

Univerzitetski Klinički Centar Srbije
2007-2024

Centar za Promociju Nauke
2016-2018

Institute of Immunology
1997

Background: Undiagnosed and untreated atherosclerotic renal artery stenosis (ARAS) can result in end-stage kidney disease (ESKD). To obtain an accurate diagnosis, it is crucial to recognize the symptoms signs suggesting (RAS) perform appropriate diagnostic treatment procedures afterward. Case Presentation: We present a case of 60-year-old female patient with hypertensive crisis, acute heart failure (HF), pulmonary edema as initial injury (AKI) caused by right RAS left occlusion presence...

10.3390/life15010082 article EN cc-by Life 2025-01-11

Background: Chronic kidney disease (CKD) is a progressive, irreversible impairment of function due to various etiologies. Numerous studies have shown that sodium-glucose cotransporter-2 inhibitors (SGLT2i) slow the progression CKD, their pleiotropic effects. Therefore, there has been an increase in interest effects not only on but also other parameters patients with CKD. The aim study was examine SGLT2i serum lipid values and CKD undergoing treatment. Methods: This retrospective data...

10.3390/metabo15040271 article EN cc-by Metabolites 2025-04-13

Reactive oxygen species play an important role in the pathogenesis of kidney ischemia/reperfusion injury (IRI) which may be influenced by immunosuppressive therapy. Pertinent to this, we investigated effects mTOR inhibitor everolimus on redox settings and activity anti-oxidative system kidneys exposed IRI.C57BL/6 mice were subjected IRI clamping both renal pedicles for 45 min. Everolimus was applied daily, subcutaneous doses (0.25 mg/kg body weight), starting 1 day before induction. Both...

10.1159/000348496 article EN American Journal of Nephrology 2013-01-01

An increase in dietary protein intake (DPI) carries a risk with respect to increased sodium intake, which further leads the development of cardiovascular morbidity peritoneal dialysis (PD) patients. Dialytic (DSR) and urinary removal (USR) are potential indicators intake. In this single-center cross-sectional study 60 prevalent PD patients, we analyze correlation DPI association between residual renal function (RRF) comorbidity grade, expressed as Davies score metabolism indices such...

10.3390/metabo14080460 article EN cc-by Metabolites 2024-08-19

Introduction. Ovarian carcinoma, being one of the most common gynecologic cancers, has highest mortality rate. The gold standard for treatment patients with advanced ovarian along angiogenesis inhibitors applied in certain stages, is cytoreductive surgery, followed by chemotherapy (CHT). use chemotherapeutic agents hemodialysis (HD) some specificities and limitations, no CHT guidelines exist treating those patients. Case report. We present a 45-year-old female patient end-stage renal disease...

10.2298/vsp231201024g article EN cc-by-sa Vojnosanitetski pregled 2024-01-01

The most frequent obstetrical cause of coagulation disorders as disseminated intravascular is placental abruption, which can be found in women without any apparent clinical disturbances or the state established preeclampsia. Hypertension occurs 5-8% all pregnancies and may complicated by Preeclampsia a complex syndrome with insufficiently clear pathophysiology based on damage vascular endothelium. As result this, generalized endothelial disruption preeclampsia, multiorgan dysfunction,...

10.2298/sarh0708465k article EN cc-by-nc Srpski arhiv za celokupno lekarstvo 2007-01-01

Background: Kidney transplantation from living donors (LD) has stagnated in many countries. This study aimed to check whether correction of LD selection practice could increase the number kidney transplantations.Methods: From January 2003 December 2012, 241 potential adult were evaluated our hospital. Outcome (mortality and end-stage renal disease-ESRD) accepted (182) was compared with unaccepted (59) donors.Results: Mortality comparable that for standardized Serbian population (SMR = 1.104;...

10.1080/0886022x.2018.1450758 article EN cc-by Renal Failure 2018-03-26

The pandemic caused by the SARS-CoV-2 virus had a great impact on population of patients treated with peritoneal dialysis (PD). This study demonstrates infection and vaccination in 66 PD their outcomes during 6-month follow-up. is first research that has studied dynamics anti-SARS-CoV-2 IgG serum effluent. In our research, 57.6% were vaccinated, predominantly Sinopharm (81.6%), which was also most frequently administered vaccine Republic Serbia at beginning immunization. During monitoring...

10.3390/vaccines12020135 article EN cc-by Vaccines 2024-01-29

Monoclonal Gammopathy of Renal Significance (MGRS) presents a diagnostic challenge due to its varied clinical manifestations.This case presentation emphasizes the importance considering MGRS as differential diagnosis in conditions characterized by worsening renal function and proteinuria, particularly with rapidly progressive course.

10.22541/au.172496754.47777390/v1 preprint EN Authorea (Authorea) 2024-08-29

The occurrence of anterior abdominal wall ulcer at the site peritoneal catheter (PC) is one rarest complications dialysis (PD). When present, it mainly caused by staphylococci which respond well to vancomycin therapy. Despite well-conducted therapy, there a tendency relapse and induce peritonitis, makes necessary remove PC change model treatment and/or re-insert another place preserve PD as method. In present study, we discuss case 53-year-old patient with end-stage kidney disease treated...

10.3390/microorganisms12122608 article EN cc-by Microorganisms 2024-12-17

To prevent organ rejection, renal transplant (RT) recipients must take immunosuppressive medicines, which make them more susceptible to infections such as tuberculosis (TB). Hepatotoxicity, can vary from asymptomatic increased liver enzymes severe failure, is the most prevalent side effect of first-line antituberculosis (AT) drugs. Treating TB in RT patients involves unique concerns since AT medications might interact with medications, potentially reducing efficacy or increasing toxicity. A...

10.7759/cureus.76263 article EN Cureus 2024-12-23

Increased peritoneal protein loss has been associated with the fast transport of small molecules, diabetes mellitus (DM), and a reduced survival in patients on dialysis (PD), although some studies did not confirm association survival. In this single-center retrospective study, we investigated relationship baseline albumin status, comorbidities including DM, 106 incident PD during period July 2005-June 2014. Five-year rate was determined using Cox-regression analysis. There were significant...

10.3390/jcm12072670 article EN Journal of Clinical Medicine 2023-04-03

Churg-Strauss syndrome (CSS) is a granulomatous small-vessel vasculitis. Asthma seen in the majority of patients with CSS, but atypical nonasthmatic forms CSS are also being recognized. We herein describe 67-year-old woman history chronic pyelonephritis and drug allergy reactions who was admitted to our hospital because worsening renal function preceded by fever, purpura, sinusitis, positive urine culture that confirmed urinary infection. She initially treated pipemidic acid for 7 days,...

10.1177/03000605211048366 article EN cc-by-nc Journal of International Medical Research 2021-09-01

Introduction. Pregnancies in women with membranous nephropathy (MN) are usually complicated by increased proteinuria and superimposed preeclampsia, this frequently results poor pregnancy outcomes. The aim of paper is to present case series pregnant MN different fetal maternal Outline cases. Case 1 presents a 25-year-old woman MN, who had relapsed nephrotic syndrome early 4.14 g/day serum albumin 30 g/L accompanied hypertension. Due missed abortion, the was terminated. Three months later her...

10.2298/sarh190221076k article EN cc-by-nc Srpski arhiv za celokupno lekarstvo 2019-01-01

Background/Aim. Chronic kidney disease (CKD) is a global health concern associated with increased cardio-vascular risks and premature mortality. Proteinuria key prognostic indicator for CKD outcome. Sodium-glucose cotransporter 2 (SGLT2) inhibitors show potential reducing proteinuria slowing progression. The aim of the study was to determine impact SGLT2 inhibitor therapy on patients by evaluating changes in level serum creatinine (sCr), 24-hour (24h) urine protein (UP), estimated glomerular...

10.2298/vsp230805061k article EN cc-by-sa Vojnosanitetski pregled 2023-10-25

Introduction. Residual renal function (RRF) in the patients treated by haemodialysis (HD) is associated not only with better volume and blood pressure control but also metabolic control. The condition of cardiovascular system significantly affects RRF. Objective. aim study was to find if there any association between regulation achieved HD ultrafiltration first year treatment maintenance Methods In this retrospective study, 53 were analyzed period 1994-2002. clearance urea (RCU) measured for...

10.2298/sarh0904160k article EN cc-by-nc Srpski arhiv za celokupno lekarstvo 2009-01-01
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