Chao Shi

ORCID: 0000-0003-1796-4028
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Research Areas
  • Cancer-related molecular mechanisms research
  • Heme Oxygenase-1 and Carbon Monoxide
  • Mycobacterium research and diagnosis
  • Birth, Development, and Health
  • Child Nutrition and Water Access
  • Lung Cancer Research Studies
  • Liver Disease Diagnosis and Treatment
  • Viral Infections and Vectors
  • Redox biology and oxidative stress
  • Chemotherapy-induced cardiotoxicity and mitigation
  • MicroRNA in disease regulation
  • Obesity, Physical Activity, Diet
  • Allergic Rhinitis and Sensitization
  • Vector-borne infectious diseases
  • Brain Metastases and Treatment
  • Medical Research and Treatments
  • Lung Cancer Treatments and Mutations
  • Cancer, Lipids, and Metabolism
  • Circular RNAs in diseases

Guiyang Medical University
2024

The Fourth People's Hospital of Ningxia Hui Autonomous Region
2024

Ningxia Medical University
2024

Nanchang University
2024

First Affiliated Hospital of Bengbu Medical College
2023

Resveratrol is an organic compound widely studied for its therapeutic uses. We investigated whether resveratrol exerts cardioprotective effects by inhibiting ferroptosis via the Sirt1/p53 pathway. A heart failure model was established aortic coarctation in Sirt1 knockout mice. The superoxide dismutase (SOD), glutathione (GSH) levels and mitochondrial morphology murine tissues were assessed at different time points to determine role of progression. cardiac function mice with evaluated...

10.1111/jcmm.17874 article EN cc-by Journal of Cellular and Molecular Medicine 2023-07-24

Abstract Bardoxolone methyl, which triggers nuclear factor erythroid 2‐related (Nrf2), has therapeutic effects against myocardial infarction, heart failure, and other diseases. Nrf2 can inhibit the activation of thioredoxin‐interacting protein (TXNIP)/NLR family pyrin domain‐containing 3 (NLRP3) pathway. Doxorubicin is an anthracycline chemotherapeutic drug associated with cardiotoxicity, limiting its clinical use. In this study, we explored specific mechanism Nrf2–TXNIP–NLRP3 pathway in...

10.1002/tox.24075 article EN Environmental Toxicology 2023-12-08

Objective This study aimed to explore whether famine exposure during early life are associated with a high risk of Type 2 Diabetes Mellitus (T2DM) in adulthood and the role socioeconomic status (SES) on this effect. Materials methods We conducted secondary data analysis based from cross-sectional survey, collected 3,355 participants born between January 1, 1941 December 31, 1966. Participants were categorized into four groups their date birth, unexposed (individuals 1963–1966), infant...

10.3389/fnut.2024.1379725 article EN cc-by Frontiers in Nutrition 2024-06-27

Purpose: Although brain metastasis (BM) from gastric cancer (GC) is relatively uncommon, its incidence has been increasing owing to advancements in treatment modalities. Unfortunately, patients diagnosed with BM have poor life expectancy. Our study aims establish a predictive model for advanced patients, thus enabling the timely diagnosis of metastasis. Patients and Methods: The clinicopathological features cohort which included 40 GC metastasis, 32 whom First Affiliated Hospital Nanchang...

10.2147/tcrm.s460647 article EN cc-by-nc Therapeutics and Clinical Risk Management 2024-06-01

<sec> <title>BACKGROUND</title> Varicella is a common infectious disease and growing public health concern in China, with increasing outbreaks Wuxi. Analyzing the correlation between climate factors varicella incidence Wuxi crucial for guiding prevention efforts. </sec> <title>OBJECTIVE</title> This study examines impact of meteorological variables on Wuxi, eastern from 2010 to 2019, offering insights interventions. <title>METHODS</title> We collected daily data case records January 1, 2010,...

10.2196/preprints.62863 preprint EN 2024-06-03
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