A5014738225- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Pharmacovigilance and Adverse Drug Reactions
- Cardiac Arrest and Resuscitation
- Fungal Infections and Studies
- Thermal Regulation in Medicine
- Antifungal resistance and susceptibility
- Respiratory and Cough-Related Research
- Intensive Care Unit Cognitive Disorders
- Antibiotic Resistance in Bacteria
- Wound Healing and Treatments
- Hepatitis B Virus Studies
- Pressure Ulcer Prevention and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Diabetes Management and Research
- Cardiovascular and Diving-Related Complications
- Viral Infections and Outbreaks Research
- Antimicrobial Resistance in Staphylococcus
- Allergic Rhinitis and Sensitization
- Organ Donation and Transplantation
- Contact Dermatitis and Allergies
- Bacterial Identification and Susceptibility Testing
- Food Allergy and Anaphylaxis Research
- Parasitic Diseases Research and Treatment
- Surgical site infection prevention
Leiden University Medical Center
2019-2025
CR2O
2024
Leiden University
2020
Ziekenhuisnetwerk Antwerpen Stuivenberg
2010-2018
ZNA Middelheim Hospital
2017
GGD Rotterdam-Rijnmond
2008
Public Health Laboratory
1999
Friesland College
1999
This Critical Appraisal aims to explore the pharmacokinetics and pharmacodynamics of medications used in organ donors after euthanasia (ODE) their impact on abdominal quality. With legalization ODE, donor pool has expanded, but it introduced complexities regarding study evaluates existing protocols Netherlands, Belgium, Spain, Canada, focusing differences medication types dosages. Additionally, a literature review assessed potential hepatotoxic effects high-dose like thiopental, propofol,...
In July 2007, two residents of a nursing home were diagnosed with acute Hepatitis B virus infection. To identify risk factors for HBV infection retrospective cohort study among was performed. Case finding included discharged diabetes patients and those receiving care. Among 32 one case chronic hepatitis found that could be identified by genotyping as the source patient cases. Diabetes finger sticks Most likely cause transmission multiclix stick device developed use in individual but used...
Triazole resistant A. fumigatus has been documented in many parts of the world. In Netherlands, incidence is now above 10% and results need for long-term parenteral therapy with liposomal amphotericin B (LAmB). The long terminal half-life LAmB suggests that intermittent dosing could be effective, making application outpatient antifungal (OPAT) possible. Here, we report our experience use OPAT Invasive Fungal Infections (IFI). All adult patients treated a 2 or 3 times weekly administration...
From a stewardship perspective it is recommended that antibiotic guidelines are adjusted to the local setting, accounting for epidemiology of pathogens. In many settings prevalence Gram-negative pathogens with resistance empiric sepsis therapy increasing. How and when escalate standard reserve antimicrobial agent, recurrent dilemma. The study objective was develop decision strategies based on microbiological clinical data, estimate number needed treat carbapenem avoid mismatch in one patient...
Background Approximately 2% of patients in primary care practice and up to 25% hospital are registered as being allergic an antibiotic. However, 90% these registrations incorrect, leading unnecessary prescription 2 nd choice antibiotics with the attendant loss efficacy, increased toxicity antibiotic resistance. To improve registration, a better understanding is needed how incorrect labels attributed. Objective investigate quality allergy registration identify determinants allergies. Design...
Objective: To describe a case of an infected atriobronchial fistula as late complication after pulmonary vein ablation, leading to septic air emboli and requiring urgent cardiac surgery. Data Sources: Clinical observation. Study Selection: Case report. Extraction: Relevant clinical information. PubMed was searched for relevant literature. Synthesis: Given its high success low rate, isolation is expected be increasingly performed worldwide. Despite success, some rare complications are...
World-wide, emerging triazole resistance increasingly complicates treatment of invasive aspergillosis (IA). In settings with substantial (>10%) prevalence resistance, empiric combination therapy both a and liposomal amphotericin B (LAmB) can be considered because the low yields susceptibility testing. To avoid toxicity while optimizing outcome, strategy monotherapy would preferable. A newly designed algorithm based on literature expert consensus provided guidance for either voriconazole or...