A5019560267- Cannabis and Cannabinoid Research
- Substance Abuse Treatment and Outcomes
- Neurotransmitter Receptor Influence on Behavior
- Mental Health Research Topics
- Prenatal Substance Exposure Effects
- Functional Brain Connectivity Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Homelessness and Social Issues
- Religion, Spirituality, and Psychology
- Behavioral Health and Interventions
- Sleep and related disorders
- Sleep and Wakefulness Research
- Impact of Technology on Adolescents
- Attention Deficit Hyperactivity Disorder
- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Forensic Toxicology and Drug Analysis
- COVID-19 and Mental Health
- Neuroscience and Neuropharmacology Research
- Advanced Causal Inference Techniques
- Neuroscience of respiration and sleep
- Alcoholism and Thiamine Deficiency
- Human-Automation Interaction and Safety
- Complex Network Analysis Techniques
- Alcohol Consumption and Health Effects
Erasmus University Rotterdam
2023-2025
University of Amsterdam
2018-2024
IVO Addiction Research Institute
2023-2024
Amsterdam Institute for Addiction Research
2019-2022
Amsterdam Neuroscience
2020
Lockdown measures aimed at limiting the number of infections and deaths from coronavirus disease 2019 (COVID-19) have introduced substantial psychosocial stressors in everyday life. We to investigate influence Dutch lockdown on cannabis use disorder (CUD) relations with change mental wellbeing experienced during lockdown.Explorative longitudinal baseline-, pre- survey study.The Netherlands, on-line between January May 2020.Community sample 120 monthly daily users reference group 63 non-using...
Abstract Background Prevalence of nitrous oxide (N 2 O) use appears to be increasing in numerous countries worldwide, and excessive has been associated with physical mental problems. Because there currently is no consensus whether N O addictive potential, we aimed evaluate the evidence for presence prevalence DSM‐5 substance disorder (SUD) symptoms users. Analysis A literature search was conducted assess any 11 SUD users experiencing those symptoms. substantial part studied more than...
Abstract Purpose of Review This narrative review provides an update our knowledge on the relation between heavy cannabis use and disorder (CUD) brain based (f)MRI studies conducted in past 5 years. Recent Findings Heavy CUD are associated with structural changes—particularly volume—as well as altered resting-state functional connectivity (RSFC) several networks regions. Task-based fMRI reveal activity users compared to controls, but consistency results is domain dependent. Heaviness use,...
While disagreement about the usefulness and appropriateness of classifying nitrous oxide as addictive is evident, urgency to address related harms undeniable. The great variety views presented in commentaries response our article highlight need for a thorough discussion on topic (N2O) addiction, utility DSM-5 case atypical substances classify substance broader health-care perspective. In [1] we argue that there are indications N2O could well be but evidence limited, systematic research...
As cannabis potency and use are increasing in newly legalized markets, it is increasingly important to measure examine the effects of cannabinoid exposure.
Alcohol is widely used, but motives for consumption vary. Since drinking are proximal predictors of initiation and escalation alcohol use, accurate measurement these crucial. This study assessed the psychometric properties – factor structure, internal consistency, test-retest reliability- 12-item, 18-item, original 20-item versions Drinking Motives Questionnaire (DMQ). We also examined associations between use outcomes using network analysis. A total 434 adults (77.4% female) completed...
Our social environment plays a crucial role in our behavior, including substance use and other impulsive sensation seeking behaviors. While most research these fields focus on the of group pressure conformity, importance attunement - tendency to harmonize with adapt find reward absence explicit – has been overlooked. In this study, we assessed psychometric properties English translation questionnaire (SAQ) how is associated age, alcohol use, cannabis impulsivity, (N = 447, 54.5% female)....
Background and aims. Many individuals aiming to reduce or quit cannabis use prefer self-guided interventions over formal treatment. In this feasibility study, we tested a two-week online intervention combining multiple evidence-based behavior change approaches. Participants. A total of 168 adults who used weekly, experienced severe disorder on average, reported being motivated participated in the baseline assessment follow-up. Setting. International study. Interventions. Participants were...
Adolescence is a critical period for the onset of depression, yet associated risks and developmental processes remain unclear. This study employed network analysis to examine associations between mental health, ecological factors, problematic smartphone use (PSU) in adolescents with major depressive disorder (MDD), while also investigating potential role left-behind experience these associations. A total 2341 (Mage = 14.99, 22.08% male, 19.99% experience) diagnosed MDD were recruited from 14...
The global increase in lenient cannabis policy has been paralleled by reduced harm perception, which associated with use initiation and persistent use. However, it is unclear how attitudes might affect the brain processes underlying Resting state functional connectivity (RSFC) within between executive control network (ECN), salience (SN), default mode (DMN) was assessed 110 near-daily users disorder (CUD) 79 controls from Netherlands Texas, USA. Participants completed a questionnaire...
While cannabis use in women is increasing worldwide, research into gender differences disorder (CUD) symptomology lacking. In response to limited effectiveness of addiction treatment, focus has been shifting from clinical diagnoses towards interactions between symptoms, as patterns symptoms and their could be crucial understanding etiological mechanisms addiction. The aim this study was evaluate the CUD symptom network assess whether there are therein.
Abstract Although cannabis use patterns differ between men and women, studies on sex differences the effects of brain cognitive control are largely lacking. Working memory (WM) is a component believed to be involved in development maintenance addiction. In this study, we evaluated association WM (load) related activity large sample, enabling us assess association. The 104 frequent users (63% men) 85 controls (53% was recorded during an N‐back task. Behavioral results showed significant...
Background: Concurrent use (co-use) of cannabis and tobacco is common associated with worse clinical outcomes compared only. The mechanisms interactions disorder (CUD) symptoms underlying co-use remain poorly understood. Methods: We examined differences in the symptom presence network configurations between weekly users who daily (co-users, n=789) or non- nondaily (nondaily co-users, n=428). Results: First, we identified a range (craving, failed reduce quit attempts, neglected...
Abstract Cannabis legislation and attitudes towards use are changing. Given that evidence from cultural neuroscience research suggests culture influences the neurobiological mechanisms underlying behaviour, it is of great importance to understand how cannabis might affect brain processes disorder. Brain activity 100 dependent users 84 controls was recorded during an N‐back working memory (WM) task in participants Netherlands (NL; = 60, 52) Texas, USA (TX; 40, 32). Participants completed a...
Abstract Cue reactivity is an important biomarker of cannabis use disorder (CUD). Despite high rates cigarette and co‐use, its role in cue remains unclear. Using a visual functional magnetic resonance imaging paradigm, we investigated interactive effects on relative to neutral priori regions interest—the amygdala, striatum, anterior cingulate cortex (ACC), ventral tegmental area (VTA), orbitofrontal cortex—and whole‐brain analysis. In our sample users controls closely matched use,...