A5100380164- Traffic and Road Safety
- Cardiac, Anesthesia and Surgical Outcomes
- Older Adults Driving Studies
- Injury Epidemiology and Prevention
- Urban Transport and Accessibility
- Anesthesia and Neurotoxicity Research
- Trauma and Emergency Care Studies
- Health disparities and outcomes
- Anesthesia and Sedative Agents
- Cardiac Arrest and Resuscitation
- Cannabis and Cannabinoid Research
- Maternal and Perinatal Health Interventions
- Occupational Health and Safety Research
- Opioid Use Disorder Treatment
- Emergency and Acute Care Studies
- Intensive Care Unit Cognitive Disorders
- Substance Abuse Treatment and Outcomes
- Suicide and Self-Harm Studies
- Human-Automation Interaction and Safety
- Forensic Toxicology and Drug Analysis
- Automotive and Human Injury Biomechanics
- Hemodynamic Monitoring and Therapy
- Disaster Response and Management
- Air Quality and Health Impacts
- Anesthesia and Pain Management
Columbia University
2016-2025
Hangzhou Normal University
2020-2025
Columbia University Irving Medical Center
2016-2025
DNV (Norway)
2022-2024
Columbia College
2010-2024
Royal College of Physicians
2009-2024
Macau University of Science and Technology
2024
Shenzhen KangNing Hospital
2022-2024
Jinzhou Kangning Hospital
2022-2024
Beijing Anding Hospital
2017-2023
<h3>Importance</h3> Exposure of young animals to commonly used anesthetics causes neurotoxicity including impaired neurocognitive function and abnormal behavior. The potential behavioral effects anesthesia exposure in children are thus important understand. <h3>Objective</h3> To examine if a single otherwise healthy was associated with development behavior later childhood. <h3>Design, Setting, Participants</h3> Sibling-matched cohort study conducted between May 2009 April 2015 at 4...
BACKGROUND: Over the past decade, safety of anesthetic agents in children has been questioned after discovery that immature animals exposed to anesthesia display apoptotic neurodegeneration and long-term cognitive deficiencies. We examined association between exposure under age 3 outcomes language, function, motor skills, behavior at 10. METHODS: performed an analysis Western Australian Pregnancy Cohort (Raine) Study, which includes 2868 born from 1989 1992. Of 2608 assessed, 321 were before...
In Brief BACKGROUND: vitro and in vivo studies of anesthetics have demonstrated serious neurotoxic effects on the developing brain. However, clinical relevance these findings to children undergoing anesthesia remains unclear. Using data from a sibling birth cohort, we assessed association between exposure setting surgery patients younger than 3 years risk developmental behavioral disorders. METHODS: We constructed retrospective cohort 10,450 siblings who were born 1999 2005 enrolled New York...
Recent animal studies have shown that commonly used anesthetic agents may serious neurotoxic effects on the developing brain. The purpose of this study was to assess association between surgery for hernia repair and risk behavioral developmental disorders in young children. We performed a retrospective cohort analysis children who were enrollees New York State Medicaid program. Our involved following birth 383 underwent inguinal during first 3 years life, sample 5050 frequency-matched age...
MORTALITY risk associated with anesthesia has been the subject of extensive research for many decades.1–5In a landmark study involving 10 academic medical centers and 599,500 surgical patients in United States during 1948–1952, Beecher Todd6found that anesthesia-related death rate was 64 deaths per 100,000 procedures, varying markedly by anesthetic agents, types providers, patient characteristics. Based on their results, Todd estimated annual number more than 5,100, or 3.3 population, which...
Abstract Ferroptosis, a novel form of programmed cell death, is characterized by iron-dependent lipid peroxidation and has been shown to be involved in multiple diseases, including cancer. Stimulating ferroptosis cancer cells may potential strategy for therapy. Therefore, ferroptosis-inducing drugs are attracting more attention treatment. Here, we showed that erianin, natural product isolated from Dendrobium chrysotoxum Lindl , exerted its anticancer activity inducing death inhibiting...
The objective of this review was to assess the effectiveness bystander naloxone administration and overdose education programs by synthesizing quantitative results reported in research literature. Studies meeting predefined criteria were identified reviewed, their synthesized through meta-analysis. Odds ratios (ORs) 95% confidence intervals (CIs) calculated for recoveries individuals who received dispensed non-medical community members, standardized mean difference test scores volunteers...
Objectives. To determine differences between hospital admitted injuries to children with preinjury attention deficit hyperactivity disorder (ADHD) and those no conditions (NO). Design. Comparative analysis, excluding fatalities, of ADHD patients (n = 240) NO 21 902), 5 through 14 years age. Outcome Measures. Demographics, injury characteristics, length stay, admission the intensive care unit, surgical intervention, disability, disposition at discharge. Data Source. Retrospective review...
Use of triggers for palliative care consultation has been advocated in intensive units (ICUs) to ensure appropriate specialist involvement patients at high risk unmet needs. The volume meeting these triggers, and thus the potential workload providers, is unknown.
Objective. In the United States, per-capita opioid dispensing has increased concurrently with analgesic-related mortality and morbidity since 1990s. To deter diversion abuse of controlled substances, most states have implemented electronic prescription drug monitoring programs (PDMPs). We evaluated impact state PDMPs on dispensing. Methods. acquired data opioids dispensed in a given quarter year for each District Columbia from 1999 to 2008 Automation Reports Consolidated Orders System...
Abstract Introduction: Immature animals exposed to anesthesia display apoptotic neurodegeneration and neurobehavioral deficits. The safety of anesthetic agents in children has been evaluated using a variety neurodevelopmental outcome measures with varied results. Methods: authors used data from the Western Australian Pregnancy Cohort (Raine) Study examine association between exposure younger than 3 yr age three types outcomes at 10 yr: neuropsychological testing, International Classification...
Malignant hyperthermia (MH) is a pharmacogenetic syndrome that variably expresses itself on exposure to triggering agents. MH prevalence in the United States not well documented. In this study, we assessed of New York State hospitals.Using hospital discharge data for years 2001 through 2005, identified all patients with diagnosis due anesthesia using International Classification Diseases, Ninth Revision, Clinical Modification code 995.86. was evaluated by demographic and clinical...
Studies of the relationship between social norms and marijuana use have generally focused on individual attitudes, leaving influence larger societal-level attitudes unknown. The present study investigated disapproval defined by birth cohort or time-period.Combined analysis nationally representative annual surveys secondary school students in United States conducted from 1976 to 2007 as part Monitoring Future study.In-school completed adolescents States.A total 986 003 grades 8, 10 12.Main...
Use of administrative data to study the effectiveness specialized palliative care is limited by lack a reliable method identify patients receiving consultation. The International Classification Diseases, Ninth Revision (ICD-9) code V66.7 has been used, but its validity for this purpose unknown.To examine ICD-9 identifying whether hospitalized received consultation.Retrospective cohort study.All age ≥18 years admitted single academic medical center between August 2013 and 2015.Sensitivity...
Abstract Editor’s Perspective What We Already Know about This Topic Article Tells Us That Is New Background Compared with neuraxial anesthesia, general anesthesia for cesarean delivery is associated increased risk of maternal adverse events. Reducing avoidable anesthetics may improve safety obstetric care. study examined events, trends, and factors potentially delivery. Methods retrospective analyzed cases without a recorded indication or contraindication to in York State hospitals, 2003...
To examine epidemiological patterns of injury fatalities in individuals with a diagnosis autism.