A5112755928- Medicinal Plant Pharmacodynamics Research
- Electrochemical sensors and biosensors
- Cytokine Signaling Pathways and Interactions
- Cancer-related molecular mechanisms research
- Neuroscience and Neural Engineering
- Multiple Myeloma Research and Treatments
- Ferroptosis and cancer prognosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Estrogen and related hormone effects
- Lymphoma Diagnosis and Treatment
- Analytical Chemistry and Sensors
- Circular RNAs in diseases
- Platelet Disorders and Treatments
- Biological and pharmacological studies of plants
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Ginseng Biological Effects and Applications
- Inflammatory Bowel Disease
- CAR-T cell therapy research
- Electrochemical Analysis and Applications
- Inflammatory mediators and NSAID effects
- Cancer Immunotherapy and Biomarkers
- Molecular Junctions and Nanostructures
- Barrier Structure and Function Studies
- MicroRNA in disease regulation
Affiliated Hospital of Hangzhou Normal University
2019-2024
Nanjing University
2012-2016
Abstract Ferroptosis, a novel form of programmed cell death, is characterized by iron-dependent lipid peroxidation and has been shown to be involved in multiple diseases, including cancer. Stimulating ferroptosis cancer cells may potential strategy for therapy. Therefore, ferroptosis-inducing drugs are attracting more attention treatment. Here, we showed that erianin, natural product isolated from Dendrobium chrysotoxum Lindl , exerted its anticancer activity inducing death inhibiting...
In this Letter, the electrochemical visualization of hydrogen peroxide inside one cell was achieved first using a comprehensive Au-luminol-microelectrode and electrochemiluminescence. The capillary with tip opening 1–2 μm filled mixture chitosan luminol, which coated thin layers polyvinyl chloride/nitrophenyloctyl ether (PVC/NPOE) gold as microelectrode. Upon contact aqueous peroxide, luminol in layer were oxidized under positive potential resulting luminescence for imaging. Due to small...
Abstract Background and aims Chemotherapy resistance in colorectal cancer have been faced with significant challenges recent years. Particular interest is directed to tumor microenvironment function. Recent work has, identified a small molecule named Divertin that prevents myosin light chain kinase 1(MLCK1) recruitment the perijunctional actomyosin ring(PAMR), restores barrier function after necrosis factor(TNF)-induced loss disease progression experimental inflammatory bowel disease....
Various subsets of diffuse large B-cell lymphoma(DLBCL) are distinguished based on molecular and immunohistochemical features. As we know, CD5 is a pan-T-cell surface marker seldom expressed in DLBCL. Large-scale studies de novo CD5+ DLBCL lacking Chinese patients.A total 139 patients with (30 109 CD5- DLBCL) who were immunophenotyped treated chemotherapy subjected to this analysis. There 85 males 54 females. Their age ranged from 17 84 years old, the median was 58 old.In study associated...
Immune checkpoint inhibitors (ICIs) are a recent breakthrough in antitumor drugs, although their overall safety has not been fully defined. Compared to conventional chemotherapy, ICIs exhibit different patterns of immunotoxicity, and immune-related adverse events (irAEs) have an immunological basis that is more toxic than usual broad spectrum manifestations involving organ systems. Early recognition symptoms timely intervention very important managing (irAEs). In this study, we report case...
MicroRNA is involved in the development of lymphoma. It reported that miR-361-3p has a tumor inhibitory effect, but its role lymphoma still unclear. The purpose this study to examine whether can inhibit and further explore related potential mechanism.In study, we first analyzed biological function transfected Raji mimicked miRNA. We also whole population stably expressed transgenic cells. Next, conducted complete micro-gene network test genetic profile differential expression stable...
Background: Candida tropicalis is the most common non-albicans species identified in immunocompromised patients, which often appears with high mortality. However, data on outcomes of treatment for fungemia patients neutropenia remain limited. Methods: In present study, 90 neutropenic adult proven fungemia, who received initial antifungal therapy, were retrospectively analyzed. Results: These results revealed that overall 8-day and 30-day mortality among entire set 22.2% 33.3%, respectively....
Abstract Background : Suppressor of cytokine signaling (SOCS) is a family proteins that respond to cytokine, growth factor and other signals, can regulate various functions tumor cells. The purpose our study was investigate the prognostic performance biological function SOCS3 in bladder cancer. Methods clinical information 80 patients with cancer at Zhejiang Provincial People’s Hospital collected protein level detected by immunohistochemistry. relationship between status parameters prognosis...
Abstract Background : Suppressor of cytokine signaling (SOCS) is a family proteins that respond to cytokine, growth factors and other signals, can regulate various functions tumor cells. The purpose our study was investigate the prognostic performance biological function SOCS3 in bladder cancer. Methods clinical information 80 patients with cancer at Zhejiang Provincial People’s Hospital collected protein level detected by immunohistochemistry. relationship between status parameters...