Francesco Ranaldi

ORCID: 0000-0003-1816-8859
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Research Areas
  • Spaceflight effects on biology
  • Muscle metabolism and nutrition
  • Phytoplasmas and Hemiptera pathogens
  • Cocoa and Sweet Potato Agronomy
  • Plant biochemistry and biosynthesis
  • Magnetic and Electromagnetic Effects
  • Food composition and properties
  • Plant Pathogenic Bacteria Studies
  • Phytochemicals and Antioxidant Activities
  • Microbial Metabolic Engineering and Bioproduction
  • Aortic aneurysm repair treatments
  • Laser Applications in Dentistry and Medicine
  • High Altitude and Hypoxia
  • Cardiac Valve Diseases and Treatments
  • Cancer, Hypoxia, and Metabolism
  • Nanoplatforms for cancer theranostics
  • Microbial Metabolites in Food Biotechnology
  • Antioxidant Activity and Oxidative Stress
  • Aortic Disease and Treatment Approaches
  • Edible Oils Quality and Analysis
  • Pregnancy and Medication Impact
  • Alkaline Phosphatase Research Studies
  • Seaweed-derived Bioactive Compounds
  • Mathematical Biology Tumor Growth
  • Porphyrin Metabolism and Disorders

University of Florence
2013-2025

Florence (Netherlands)
2016

In adult tissue the quiescent state of a single cell is maintained by steady conditions its own microenvironment for what concern both cell-cell as well cell-ECM interaction and soluble factors concentration. Physiological or pathological can alter this through an imbalance insoluble that trigger cellular phenotypic response. The kind response depends many but one most important concentration cytokines sensed target cell. addition, due to intrinsic plasticity types, every able, in same...

10.1186/1478-811x-8-20 article EN cc-by Cell Communication and Signaling 2010-09-07

Estrogen receptor β (ERβ) is the most highly expressed subtype in colon epithelium and mediates protective effect of estrogen against development cancer. Indeed, expression this inversely related to colorectal cancer progression. Structurally estrogen-like compounds, including vitamin E components, affect cell growth by binding ERs. In present study, proliferation was measured counting a Bürker hemocytometer, ERβ Real-Time qPCR immunoenzymatic methods. The results obtained show that natural...

10.3390/ijms26052305 article EN International Journal of Molecular Sciences 2025-03-05

Laser therapy is used in physical medicine and rehabilitation to accelerate muscle recovery sports prevent damages produced by metabolic disturbances inflammatory reactions after heavy exercise. The aim of this research was get insight into possible benefits deriving from the application an advanced IR laser system counteract deficits energy metabolism stimulate hypotrophic tissue. We studied effect treatment on proliferation, differentiation, cytoskeleton organization global protein...

10.1039/c2mb25398d article EN Molecular BioSystems 2013-01-01

Abstract Xylella fastidiosa is a Gram‐negative, xylem‐limited, bacterium which responsible, in Italy, for the olive quick decline syndrome ( OQDS ). The disease caused by subspecies pauca and emerged few years ago Apulia province of Lecce, Salento peninsula, on Olea europaea plants . X. can infect different plant species well known California as causal agent Pierce's grape. Infections susceptible hosts with are to result xylem vessel occlusions, water movement impairment, accordingly induce...

10.1111/jph.12596 article EN Journal of Phytopathology 2017-06-19

Regular physical activity is associated with a reduced risk of coronary heart disease, as it probably modifies the balance between free-radical generation and antioxidant activity. On other hand, however, acute increases oxygen uptake leads to temporary imbalance production reactive nitrogen species (RONS) their disposal: this phenomenon called oxidative stress. Proteins are one most important oxidation targets during exercise carbonylation common protein modifications. In cells there...

10.1039/c0mb00106f article EN Molecular BioSystems 2010-11-22

DNA-based approaches were used to characterize a strain (Salento-1) of Xylella fastidiosa obtained from an olive plant suffering the syndrome quick decline in Apulia (South Italy). Salento-1 was indistinguishable CoDiRO previously isolated and assigned to  X. subsp. pauca. Based on our results comparative analysis with reported data, subspecies pauca , multiplex may invade throughout world (California, Italy, Argentina Brazil). The has been deposited National Collection Plant Pathogenic...

10.14601/phytopathol_mediterr-17867 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2016-03-01

The development of analytical devices that can allow an easy, rapid and cost-effective measurement multiple markers, such as progesterone β-hCG, could have a role in decreasing the burden associated with pregnancy-related complications, ectopic pregnancies. Indeed, pregnancies are significant contributor to maternal morbidity mortality both high-income low-income countries. In this work, effective highly performing electrochemical strip for combo determination β-hCG was developed. Two...

10.3390/ijms242015381 article EN International Journal of Molecular Sciences 2023-10-19

Xylella fastidiosa causing disease on different plant species has been reported in several European countries, since 2013. Based multilocus sequence typing (MLST) results, there is evidence of repeated introductions the pathogen Spain and France. In contrast, Salento area Apulia (Puglia) Southern Italy, existence a unique Apulian MLST genotype X. , olive quick decline syndrome (OQDS; also referred to as “CoDiRO” or “ST53”) was proven, this tentatively ascribed subsp. pauca . order acquire...

10.14601/phytopathol_mediterr-22263 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2018-02-01

Abstract Our results show that the phosphate ion is a nonlinear competitive inhibitor of Pinus pinea isocitrate lyase. In addition, this compound induces sigmoidal response enzyme, which usually exhibits standard Michaelis-Menten kinetics. This peculiar behavior ofP. lyase could be explained by dimer (two-site) model, in binds cooperatively, but affinity vacant site for substrate (the magnesium-isocitrate complex) remains same. As result, interaction with free enzyme produces an...

10.1104/pp.124.3.1131 article EN PLANT PHYSIOLOGY 2000-11-01

The effects of the phenolic compounds extra virgin olive oil (EVOO) on AGS cells have never been studied so far, which is aim this study. profiles main components in EVOOs, mainly secoiridoid derived from transformation oleuropein during milling process, were evaluated and compared. Oils different origins aiming at verifying whether chemical differences composition dry extracts played a role metabolism maintaining cellular redox state cells. following key enzymes some metabolic pathways...

10.3390/antiox12071347 article EN cc-by Antioxidants 2023-06-27

Pâté is a by-product of olive oil production which represents an abundant source phenolic compounds and can be used for food formulation, reducing its environmental impact promoting circular economy. In this context, the effects hydroalcoholic extract pâté were evaluated first time in AGS human cell line commonly as model gastric mucosa. was obtained from Tuscan olives; total content 16.6 mg/g dried extract, with verbascoside secoiridoid derivatives most phenols. The did not alter viability,...

10.3390/ijms24097959 article EN International Journal of Molecular Sciences 2023-04-27
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