A5003661214- SARS-CoV-2 and COVID-19 Research
- Bacillus and Francisella bacterial research
- COVID-19 Clinical Research Studies
- Animal Disease Management and Epidemiology
- Bacteriophages and microbial interactions
- Plant responses to water stress
- Agronomic Practices and Intercropping Systems
- SARS-CoV-2 detection and testing
- Immunotherapy and Immune Responses
- Animal Virus Infections Studies
- Magnolia and Illicium research
- Influenza Virus Research Studies
- Respiratory viral infections research
National Vaccine and Serum Institute
2022-2024
Shanghai Municipal Center For Disease Control Prevention
2024
Seasonal influenza A virus subtype H3N2 (A/H3N2) circulates globally and has been linked to higher hospitalization rates summer outbreaks in temperate regions. Here, A/H3N2 circulation Shanghai, China was systematically studied using data materials generated by the Shanghai surveillance network from 2005 2023. Time-series analysis of incidence subtyping showed that co-circulated with other (sub)types dominated multiple seasonal peaks, preferentially summer. Whole genomes 528 representative...
In response to the fast-waning immune and great threat of Omicron variant concern (VOC) public, we report pilot-scale production an inactivated vaccine candidate that induces high levels neutralizing antibody titers protect against virus. Here, demonstrate is safe effective in recalling responses HB02, Omicron, Delta viruses after one or two doses BBIBP-CorV. addition, efficient productivity good genetic stability manufactured proved. These results support further evaluation a clinical trial.
It has been reported that the novel coronavirus (COVID-19) caused more than 286 million cases and 5.4 deaths to date. Several strategies have implemented globally, such as social distancing development of vaccines. severe acute respiratory syndrome 2 (SARS-CoV-2) variants appeared, Alpha, Beta, Gamma, Delta, Omicron. With rapid spread rapidly changing mutants, a broad-spectrum multivalent vaccine is considered be most effective way defend against constantly mutating virus. Here, we evaluated...
Due to a large number of mutations in the spike protein and immune escape, Omicron variant (B.1.1.529) has become predominant concern (VOC) strain. To prevent disease, we developed candidate inactivated vaccine (Omicron COVID-19 Vaccine (Vero Cell), Inactivated). evaluate safety vaccine, tested repeat-dose toxicity Sprague-Dawley (SD) rats. The doses were administered randomly three groups: physiological saline solution (control), aluminum adjuvant PBS (adjuvant group), low-dose high-dose...