A5059451886- Oral microbiology and periodontitis research
- Corporate Finance and Governance
- Renal cell carcinoma treatment
- Financial Markets and Investment Strategies
- Cancer Genomics and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Genetics and Neurodevelopmental Disorders
- Cancer-related gene regulation
- Cancer Mechanisms and Therapy
- Wnt/β-catenin signaling in development and cancer
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Periodontal Regeneration and Treatments
- Cancer-related Molecular Pathways
- Dental Implant Techniques and Outcomes
- Auditing, Earnings Management, Governance
- Stock Market Forecasting Methods
- Dental Radiography and Imaging
- Uterine Myomas and Treatments
- Health and Medical Research Impacts
- Pancreatic and Hepatic Oncology Research
- Animal Genetics and Reproduction
- Advanced Breast Cancer Therapies
- Working Capital and Financial Performance
- Maternal and fetal healthcare
- Oral and gingival health research
Pondicherry University
2014-2023
Cooper University Hospital
2022
Thai Moogambigai Dental College and Hospital
2020-2022
Michigan State University
2015-2020
Ascension Providence Hospital
2020
Providence Hospital
2020
The Barbara Ann Karmanos Cancer Institute
2019
National Eye Institute
2016
National Institutes of Health
2016
Mayo Clinic in Arizona
2016
Ocular coloboma is a common eye malformation resulting from incomplete fusion of the optic fissure during development.Coloboma often associated with microphthalmia and/or contralateral anophthalmia.Coloboma shows extensive locus heterogeneity causative mutations identified in genes encoding developmental transcription factors or components signaling pathways.We report an ultra-rare, heterozygous frameshift mutation FZD5 (p.Ala219Glufs*49) that was independently two branches large family...
In this paper, we evaluate the cross sectional relationship between firm characteristics, financial leverage, and stock returns for Indian market. The study finds that there are strong size value effects existing in return pattern of stocks, also a complex leverage context. Gibbons, Ross, Shanken (GRS) test confirms robustness three factor model with market, size, over Fama-French (1993) most cases. Wald same determining portfolio Further, estimates show portfolios formed using breakpoints...
As a novel technology that utilizes the endogenous immune defense system in bacteria, CRISPR/Cas9 has transcended DNA engineering into more pragmatic and clinically efficacious field. Using programmable sgRNA sequences nucleases, effectively introduces double strand breaks target genes within an entire organism. The applications of CRISPR range from biomedicine to drug development epigenetic modification. Studies have demonstrated mediated targeting various tumorigenic effector proteins...
We evaluate the ability of alternative asset pricing models in explaining returns on various characteristic (company size and value) sorted prior return ranked portfolios. Data is employed from January, 1997 to June, 2012 for 488 companies listed BSE-500 index. find that Fama-French three factor model performs better than one capital mean excess also observe partly explains long term, reversal, momentum profits. Asset results are found be vibrant alternate versions company value factors...
Recently, the discussion on implications of irreproducibility in sciences has been brought into spotlight. This topic discussed for years literature. A multitude reasons have attributed to this issue; one commonly labeled culprit is overuse p value as a determinant significance by scientific community. Both scientists and statisticians questioned use null hypothesis testing basis analysis. survey current issues at hand research emphasizes potential causes issue, impacts that can drug...
Purpose The present study aims to verify whether there is a positive (negative) role being played by the institutional investors on loss-making companies' performance. Design/methodology/approach authors employ panel data regression and two-step system generalised method of moments (SYS-GMM) test above objective. Findings empirical results clearly show that no relation found between Research limitations/implications findings might have significant implications for firms improve firms'...
4579 Background: Cabo shows robust clinical activity in advanced clear cell RCC. nccRCC, a heterogeneous mix of diseases, have been underrepresented trials and effective systemic therapy is lacking. We retrospectively characterized the toxicity cabo nccRCC. Methods: Medical records from nccRCC patients (pts) treated with across 18 institutions were reviewed. captured baseline characteristics, outcomes genomic alterations by next-generation sequencing (NGS). Objective response rate (ORR) was...
Aim:The monocyte-to-high-density lipoprotein cholesterol ratio (MHR) has currently been proposed as an indicator of inflammation.The aim the present study was to assess relationship between and periodontal health disease.Materials methods: A total 90 patients were selected for -30 healthy (group I) 60 periodontitis (groups II III).All subjected blood sampling serum malondialdehyde (MDA), high-density (HDL) levels monocyte counts estimated.Results: Monocyte-to-high-density 80.64 ± 28.71 with...
Kasabach-Merritt phenomenon is a process where the presence of vascular irregularity within Kaposiform hemangioendothelioma or tufted angioma leads to constitutive coagulation factor activation and development chronic disseminated intravascular (DIC). A similar has been seen in other tumors but rarely described. 42-year-old woman presented hospital following worsening easy bruising bleeding. She was ultimately found have massive uterine fibroid that led cascade subsequent DIC. Following...
e12622 Background: The rate of contralateral prophylactic mastectomy (CPM) in the United States has more than tripled past decade. majority women who undergo CPM have no major genetic or familial risk factors for disease. In patients standard risk, not been shown to decrease breast cancer mortality. We hypothesized that a higher sense loss aversion which may distort risk-benefit ratio at time when they are vulnerable because fear and control. Methods: conducted survey 38 underwent 28 had...