A5087501204- Memory Processes and Influences
- Carbohydrate Chemistry and Synthesis
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Deception detection and forensic psychology
- Memory and Neural Mechanisms
- Glycosylation and Glycoproteins Research
- Proteoglycans and glycosaminoglycans research
- Child and Animal Learning Development
- Enzyme Catalysis and Immobilization
- Chemical Synthesis and Analysis
- Visual and Cognitive Learning Processes
- Autism Spectrum Disorder Research
- Asymmetric Synthesis and Catalysis
- Neural and Behavioral Psychology Studies
- Synthesis and biological activity
- Click Chemistry and Applications
- Crystallography and molecular interactions
- Synthesis and Characterization of Heterocyclic Compounds
- Chemical Reaction Mechanisms
- HIV/AIDS drug development and treatment
- Synthesis and Biological Evaluation
- Intelligent Tutoring Systems and Adaptive Learning
- Language Development and Disorders
- Synthetic Organic Chemistry Methods
University of Manchester
2013-2023
Engineering and Physical Sciences Research Council
2017-2018
Biotechnology and Biological Sciences Research Council
2017-2018
City, University of London
1997-2015
University of Sussex
1995-2014
Czech Academy of Sciences, Institute of Biotechnology
2012
Cancer Research UK
2009
University of West London
2007
The Kids Research Institute Australia
2005
The University of Western Australia
2005
Abstract The old yellow enzyme (OYE) family is a large group of flavin‐dependent redox biocatalysts with major applications in the industrial reduction activated alkenes. These enzymes have broad specificity, are relatively stable, and been made available quantities by using conventional genetic methods. catalytic cycle comprises two half‐reactions: flavin mononucleotide NAD(P)H followed oxidation through stereospecific CC bond wide range Recent years witnessed extensive investigation these...
First-year psychology students took multiple-choice examinations following each of 4 lecture courses and 3 laboratory research methods courses. One course was later retested. Students indicated state memory awareness accompanying answer: recollective experience (remember), just know (know), feeling familiarity (familiarity), or guess. On the courses, higher performing differed from other because they had more remember responses. methods, knew more, in delayed retest, now rather than...
Abstract In yes/no and two - alternative forced choice recognition tests, subjects reported one of three states awareness when selecting each target: remembering, knowing, or guessing. A remember response indicated recollection the target's occurrence in study list. know target was familiar experimental context but not recollected. guess selected absence either remembering knowing. Experiments 1 2, level processing influenced responses and, Experiment 3, generating versus reading similarly...
The broccoli constituent sulforaphane (1-isothiocyanate-4-methylsulfinylbutane) has previously been shown to protect rats against 9, 10-dimethyl-1, 2-benz[a]anthracene tumori-genesis, thought be due, at least in part, induction of phase II detoxification. We investigated the ability also inhibit I enzyme cytochrome P450 isoenzyme 2E1 (CYP2E1), which is responsible for activation several carcinogens, including dialkylnitros-amines. Using p-nitrophenol hydroxylation assay microsomes from...
We examined the efficacy of naltrexone (an opioid antagonist) for alcohol dependence in a sample alcohol-dependent men.A 12-week randomized placebo-controlled clinical trial.The outpatient clinic combined war veteran and general teaching hospital Melbourne, Australia.Male subjects recruited from community groups.Alcohol-dependent were treated with 50 mg or placebo daily 12 weeks. Both treatment groups attended weekly education support group. Subjects assessed weekly.Primary study outcomes...
Priming in an indirect test of stem completion should reflect involuntary memory, but can be accompanied by conscious awareness the past (involuntary memory) or unaccompanied such unconscious memory). We adapted method opposition developed Jacoby, Woloshyn, and Kelley (1989) to obtain a measure stem-completion priming that only memory. Subjects completed stems with first word coming mind, wrote down different if came mind had been previously encountered. Facilitatory was expected when...
The wetting behavior of homopolymer on a chemically identical polymer brush is mathematically equivalent to the interaction between pair opposing brushes in matrix parent homopolymer. We examine both systems using self-consistent field theory (SCFT) with new highly efficient and accurate algorithm. Our calculations provide compelling evidence that global minimum free energy curve remains at finite film thickness, implying brush/homopolymer interfacial tension, γb/h, always positive favoring...
Abstract We show that pentaerythritol tetranitrate reductase (PETNR), a member of the ‘ene’ old yellow enzyme family, catalyses asymmetric reduction variety industrially relevant activated α,β‐unsaturated alkenes including enones, enals, maleimides and nitroalkenes. have rationalised broad substrate specificity stereochemical outcome these reductions by reference to molecular models enzyme‐substrate complexes based on crystal complex PETNR with 2‐cyclohexenone 4a . The optical purity...