A5003288604- Biliary and Gastrointestinal Fistulas
- Acute Ischemic Stroke Management
- Multiple Sclerosis Research Studies
- Ophthalmology and Eye Disorders
- Gallbladder and Bile Duct Disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Pediatric Hepatobiliary Diseases and Treatments
- Peripheral Neuropathies and Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Autoimmune and Inflammatory Disorders
- Cancer Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Infectious Encephalopathies and Encephalitis
- Viral Infections and Immunology Research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Anesthesia and Sedative Agents
- Musculoskeletal pain and rehabilitation
- Rheumatoid Arthritis Research and Therapies
- Migraine and Headache Studies
- Polyomavirus and related diseases
- Neurosurgical Procedures and Complications
- Genetics and Neurodevelopmental Disorders
- Myasthenia Gravis and Thymoma
- Pharmaceutical Practices and Patient Outcomes
- Cerebrovascular and Carotid Artery Diseases
University of Kragujevac
2015-2023
Clinical Centre of Kragujevac
2017-2023
Institut za Zdravstvenu Zastitu Majke i Deteta
1993
Marienkrankenhaus Kassel
1972
Introduction. Acute intermittent porphyria is a rare metabolic disorder of the hem biosynthetic pathway that can cause severe neurological symptoms involving central, autonomic and peripheral nervous system. Diagnosis may be delayed due to variable mimic other diseases. Case report. A 23-year-old woman with abdominal pain, constipation, progressive development quadriparesis bulbar palsy was admitted our intensive care unit two weeks after undergoing dental surgery. Preventive antibiotic...
Purpose: The purpose of this study was to examine if depression and fatigue affect event-related brain potentials (ERPs) in patients with relapsing–remitting multiple sclerosis, assess the significance ERP as an indicator cognitive impairment. Methods: A total 81 sclerosis 32 healthy control subjects participated study. Cognitive functions were evaluated using a standard PASAT, symbol digit modality test, ERP. degrees depressive symptomatology assessed Beck Depression Inventory, Fatigue...
Abstract Background Clinically relevant potential drug-drug interactions are considered preventable adverse drug reactions. Objective The aim of this study was to ascertain the frequency in acute ischemic stroke patients and explore factors associated with occurrence potentially contraindicated interactions. Methods This observational retrospective cohort nested case-control carried out among treated for at Neurological Intensive Care Unit Clinical Centre Kragujevac, Serbia. each day...
This paper explores the accidents that occurred in railway system of Serbian Railways from 2006 to 2012. The total number sample observed includes 3983 accidents, which 2725 or 68.41% were caused by human factor. One major contemporary problems – global climate change and increase average temperatures – has not yet been considered context external factors for increasing risk accidents. air pressure become accepted as an factor, addition temperature. It is assumed temperature have a...
Recurrent painful ophthalmoplegic neuropathy (RPON) is a very rare disease characterized by recurrent attacks (at least two) of unilateral headache associated with ipsilateral ophthalmoplegia due to paresis one or more cranial motor nerves, not any orbital, parasellar, posterior fossa lesions. The differential diagnoses for this condition are broad. In addition disability during an acute attack, could also cause permanent neurologic deficit. understanding RPON pathogenesis has changed over...
Abstract Stroke is one of leading causes death worldwide. Different frequency stroke occurence observed in days the week and months year, incidence has irregular time pattern. We analyzed 516 patients who had acute were treated Clinic Neurology, Clinical Center Kragujevac from January 1, 2013 to 2014, mean age 72,11±11,52. Statistical analysis conducted out using SPSS software version 20.0. used descriptive statistic, student T-test, chi-square or Fisher exact test. Friday day we found most...
This paper describes a physical vapor deposition (PVD) coating equipment, as well the according parameters suitable to provide hard nitride coatings on broaches up length of 2.2 m. The octagonal-shaped vacuum chamber reached height 4.5 m and diameter 1.2 To explore sufficient reproducible film, an adhesion test sample tools were subjected pretreatment in Cr2+ Ar+ high-power impulse magnetron sputtering (HIPIMS) plasma prior actual film deposition. Two methods applied: reactive unbalanced...
Background. Combined oxidative phosphorylation deficiency-1 (COXPD1) resulting from a mutation in the G elongation factor mitochondrial 1 (GFM1) gene is an autosomal recessive multisystem disorder arising defect system. Death usually appears first weeks or years of lifespan. Case. We report male patient with ventriculomegaly diagnosed 8th month pregnancy. The delivery was done by caesarean section and respiratory failure occurred immediately after birth. Hypoglycemia, lactic acidosis,...
Cerebral small vessel disease (CSVD) and metabolic syndrome were separately associated with cognitive impairment depression. However, whether adds to depression in patients who already have CSVD remained unanswered.The aim of our study was investigate the association lacunar lesions or white matter hyperintensities.This prospective cohort conducted at Neurology Clinic, Clinical Center, Kragujevac, Serbia. Main outcomes assessment, assessment among hospitalized without CSVD.The included 74...
Abstract Interferon beta is a safe and efficacious treatment for relapsing multiple sclerosis (MS). However, there some evidence that uric acid, scavenger of peroxynitrite, involved in MS pathology increasing serum acid levels might have beneficial therapeutic effects. The aim this study to investigate patients before after long-term interferon treatment. Blood samples from 101 (53 receiving 1a 48 1b treatment; 28 male 73 female; mean age at onset 32,4±7,3 years; duration disease 5,1±3,2...
Abstract Hip osteoarthritis (OA) is a degenerative, progressive musculoskeletal system disease in adult individuals. Both genders demonstrate similar prevalence at 11.5% for men and 11.6% women. During the initial stage of hip OA, conservative treatments may significantly decrease pain, provide functional improvement enhance health related quality life (HRQoL). The aims study were to evaluate patients with estimate impact comprehensive rehabilitation intervention on their HRQoL. This was...
Introduction. Periventricular nodular heterotopia (PNH) is a developmental malformation of the cerebral cortex characterized by abnormal migration neurons into cortical plate and often associated with drug-resistant focal epilepsy. Case report. A 33-year-old female patient suffered from epilepsy, which was predominantly seizures, occasional seizures that had onset progressed bilateral tonic-clonic seizures. Magnetic resonance imaging showed heterotopic nodules in occipital horns lateral...
Introduction The health-related quality of life (HRQoL) people with (Pw) multiple sclerosis (MS) is usually deteriorated. It has been recently suggested that comorbidities may have the negative influence on PwMS, but according to best our knowledge, only one study investigated, although in a very small cohort, impact individual comorbidity PwMS. aim investigation was assess, an international, multicentric study, comorbid seizure/epilepsy HRQoL Methods We conducted cross-sectional at numerous...
Abstract Thrombosis of veins and venous sinus (CVT) is the rare cerebral vascular disorder which makes less than 1% all strokes. sinuses picturesquely called “мајоr neurological forger” since it characterized by very varied clinical picture. Among various causes CVT, can be infective or non-infective nature, congenital hyper coagulations especially stand out, diagnosis based on highly sophisticated diagnostic tests. We present case a female patient, 36 years old, who was hospitalized at...
A phenomenon that does not quite rise to the level of research misconduct occurs when faculty responsible for assisting PhD students fail fulfill role. The factors may affect readiness help with a methodological issue concerning sampling was essential designing dissertation were revealed in this study - simulated student-professor interaction study. Of 153 asked assist, 47% failed respond and those who responded, only 21% made an appointment student. Results our showed behavior university...
Our aim was to determine risk factors for and frequency of potential drug-drug interactions (pDDIs) among hospitalized patients with myasthenia gravis (MG).This a retrospective cross-sectional study the-first time MG or because the exacerbation at Neurology Clinic Clinical Center Serbia, Belgrade. Medical records discharge summaries over 10-year period were reviewed. The pDDIs identified by means Micromedex, multivariate regression methods used reveal predictors number per patient.The...
Objectives: The first objective of our study was to determine differences between groups patients receiving disease modifying therapy (DMTs) (INFβ-1a and INFβ-1b), without DMTs a control group, in terms neuropsychological tests event-related brain potentials (ERP). second factors that may serve assess the risk cognitive impairment with relapsing remitting multiple sclerosis (RRMS). Methods: A total 81 RRMS (mean age 41.09 ± 8.71 years old, 51 women, mean duration 133.05 76.56 months) 32...
Our aim was to determine the prevalence of potential drug-drug interactions (pDDIs) and identify relevant factors associated with occurrence most dangerous or contraindicated pDDIs (pCDDIs) in hospitalized patients spontaneous intracerebral hemorrhage (sICH). A retrospective cross-sectional study performed enrolling all consecutive sICH treated at Neurological Intensive Care Unit, Clinical Center Kragujevac, Serbia, during three-year period (2012-2014). The inclusion criteria encompassed...