A5026094677- Cerebrovascular and Carotid Artery Diseases
- Systemic Sclerosis and Related Diseases
- Spinal Fractures and Fixation Techniques
- Urticaria and Related Conditions
- Autoimmune and Inflammatory Disorders Research
- Porphyrin Metabolism and Disorders
- Breast Lesions and Carcinomas
- Sarcoidosis and Beryllium Toxicity Research
- Methemoglobinemia and Tumor Lysis Syndrome
- Coronary Artery Anomalies
- Liver Disease and Transplantation
- Medical Imaging and Analysis
- Case Reports on Hematomas
- HER2/EGFR in Cancer Research
- SARS-CoV-2 and COVID-19 Research
- Research on Leishmaniasis Studies
- Trauma Management and Diagnosis
- Intracranial Aneurysms: Treatment and Complications
- Environmental Science and Water Management
- Renal and Vascular Pathologies
- Fetal and Pediatric Neurological Disorders
- Glioma Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Liver Disease Diagnosis and Treatment
- Heme Oxygenase-1 and Carbon Monoxide
University of Nis
2020-2024
Klinički centar Niš
2020-2022
Microglia are key players in the brain’s innate immune response, contributing to homeostatic and reparative functions but also inflammatory underlying mechanisms of neurodegeneration. Targeting microglia modulating their function may have therapeutic potential for mitigating neuroinflammation The anti-inflammatory properties essential oils suggest that some components be useful regulating microglial microglial-associated neuroinflammation. This study, starting from ethnopharmacological...
The technical complexity of gene expression profiling in routine practice has necessitated the use surrogate molecular classification breast cancer, based on immunohistochemical analyses. Background and objectives: aim this study was to compare differences between histological subtypes invasive lobular carcinoma (ILC) breast, order be able predict behavior prognosis disease, as well effectively determine therapy. Material Methods: This included 263 cases ILC diagnosed over a seven-year...
Introduction. Acute intermittent porphyria is a rare metabolic disorder of the hem biosynthetic pathway that can cause severe neurological symptoms involving central, autonomic and peripheral nervous system. Diagnosis may be delayed due to variable mimic other diseases. Case report. A 23-year-old woman with abdominal pain, constipation, progressive development quadriparesis bulbar palsy was admitted our intensive care unit two weeks after undergoing dental surgery. Preventive antibiotic...
Cirrhosis is the final stage of numerous chronic liver diseases.The disease most often occurs as a result alcohol consumption and infection with hepatitis C B viruses.Over 3 million people die globally consumption.Prognostic scores have been developed to estimate survival rates.The MELD score (model for endstage disease) used today in prognosis short-term patients decompensated cirrhosis.This prospective/retrospective study was conducted on sample 56 (52 male 4 female) an average age 55.23 ±...
Background/Aim. Acoustic evoked potentials (AEPs) represent an electrophysiological method used in diagnosing pathological changes of the brain stem (BSt), acoustic nerve (its peripheral and central part), patients coma, confirmation cerebral death, etc. The response includes seven negative waves which are generated structures BSt vascularized by arteries posterior circulation. However, everyday practice, due to their constancy, first five followed. vertebral artery hypoplasia (VAH) is...
Some variations of the cerebral arterial circle (CAC) are associated with an increased risk for development various pathological conditions. This paper aimed to determine prevalence hypoplastic arteries CAC and emphasize limited possibility their visualization by computed tomography angiography (CTA).The research was performed on 400 adult cadavers macro- microdissection arteries. Each case photographed diameter measured digitally, analyzing photographs bases brain in ImageJ program.The...
Vertex epidural hematoma (EDH) is an uncommon type of EDH.The management vertex EDH a challenge for neurosurgeons, as there no proper consensus on the treatment modality.Our patient had delayed clinical deterioration with development paraparesis and deep somnolent state.After immediate head CT was performed, which showed massive at vertex, underwent urgent operation.The postoperative course went satisfactorily complete withdrawal all neurological deficits control scan evacuation...
The aim of the paper was to determine clinical significance pathological finding and characteristics auditory evoked potentials (AEP) in patients with posterior circulation stroke caused by vertebral artery hypoplasia (VAH). study enrolled 71 patients, 31 them had stroke. results examinations showed that AEP statistically significantly correlated (PCS) finding. Changes amplitude presented a prominent feature require further investigations.
Ocrelizumab is a disease-modifying therapy (DMT) for active relapsing and early primary progressive multiple sclerosis (MS).During the COVID-19 pandemic, it was speculated that ocrelizumab might increase risk of in patients with MS.The aim to assess infection MS treated ocrelizumab.Our study included who met revised McDonald criteria were at University Clinical Centre Niš.The diagnosis made by positive PCR (polymerase chain reaction) or antigen test.The severity disease estimated based on...
Human toxocariasis is a parasitic infection caused by the roundworms Toxocara canis or cati.Toxocara larvae can cross blood-brain barrier leading to neurotoxocariasis.Involvement of central nervous system extremely rare.The clinical presentation consists wide spectrum neurological manifestation.Here we present case 63-year-old woman with rapidly progressive form neurotoxocariasis.Her initial head computed tomography scan showed multiple hypervascular lesions in her brain and contrast...
Ophthalmic artery (OA) is a potential origin of aneurysms.We present patient with giant OA aneurysm, sudden onset psychomotor agitation at the admission.Digital subtraction angiography showed an aneurysm originating from ophthalmic segment left internal carotid irregular shape, diameters up to 6.5 x 4.5 mm, while neck was 4 mm wide.On computed tomography angiography, seen as much larger and round, 4.7 cm in diameter calcified wall.In further course treatment, microcatheter placed lumen...
Multicentric glioblastomas, which simultaneously involve supra-and infratentorial areas, are rare.In our patient, the magnetic resonance imaging (MRI) of cervical and thoracic spine was performed, verified spinal intramedullary tumor at level C6 from Th1 to Th4 segment.During surgery, tumor, had macroscopic characteristics glioblastoma encountered it partially resected.Pathohistological findings that IDH-wild type glioblastoma.The MRI brain performed after showed right temporoparietal...