A5020644844- Streptococcal Infections and Treatments
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Antimicrobial Resistance in Staphylococcus
- Neonatal and Maternal Infections
- Silicon and Solar Cell Technologies
- Thin-Film Transistor Technologies
- Glycosylation and Glycoproteins Research
- Chalcogenide Semiconductor Thin Films
- Electrocatalysts for Energy Conversion
- Toxin Mechanisms and Immunotoxins
- Quantum Dots Synthesis And Properties
- Proteoglycans and glycosaminoglycans research
- Bacterial Identification and Susceptibility Testing
- Copper-based nanomaterials and applications
- ZnO doping and properties
- Inflammasome and immune disorders
- Silicon Nanostructures and Photoluminescence
- Electron and X-Ray Spectroscopy Techniques
- Fibroblast Growth Factor Research
- Biochemical and Structural Characterization
- Semiconductor materials and interfaces
- Electrochemical Analysis and Applications
- Infective Endocarditis Diagnosis and Management
- Restraint-Related Deaths
National Institute for Materials Science
2014-2025
University of Groningen
2021-2025
Helmholtz-Zentrum Berlin für Materialien und Energie
2010-2016
AT&T (United States)
1989-2003
Friedrich Schiller University Jena
1995-2000
University of Lübeck
1997
University of Münster
1977-1996
Centre National de la Recherche Scientifique
1994
Lund University
1994
University of Oklahoma Health Sciences Center
1993
A NaF/KF postdeposition treatment (PDT) has recently been employed to achieve new record efficiencies of Cu(In,Ga)Se2 (CIGSe) thin film solar cells. We have used a combination depth-dependent soft and hard X-ray photoelectron spectroscopy as well absorption emission gain detailed insight into the chemical structure CIGSe surface how it is changed by different PDTs. Alkali-free CIGSe, NaF-PDT NaF/KF-PDT absorbers grown low-temperature coevaporation interrogated. find that alkali-free surfaces...
The molecular population genetics and pathogenic potential of North American European invasive strains Streptococcus pyogenes were assessed. Isolates from recent infections in the 1920s 1930s characterized for multilocus enzyme genotype allelic variation gene (speA) that encodes streptococcal pyrogenic exotoxin (SPE) A (scarlet fever toxin). subset was studied genes encode SPE B streptokinase. All contemporary assigned to electrophoretic types (ETs) 1 2 synthesize have speA2 speA3 variants,...
Abstract The enterotoxins produced by Staphylococcus aureus are the most potent mitogens known. They belong to a group of distantly related mitogenic toxins that differ in other biologic activities. In this study we have compared molecular mechanisms which these activate human T lymphocytes. We used staphylococcal A E, toxic shock syndrome toxin, streptococcal erythrogenic and C (scarlet fever toxins, (ET)A, ETC), soluble mitogen Mycoplasma arthritidis. found all can both CD4+ CD8+ cells...
The differences between toxic or septic shocks in humans during infections by streptococci and gram-negative bacteria remain to be fully characterized. For this purpose, a quantitative study of the cytokine-inducing capacity Streptococcus pyogenes erythrogenic (pyrogenic) exotoxins (ETs) A C, heat-killed S. bacteria, Neisseria meningitidis endotoxin (lipopolysaccharide [LPS]) on human peripheral blood mononuclear cells (PBMC) monocytes has been undertaken. levels interleukin-1 alpha (IL-1...
The pyrogenic (erythrogenic) exotoxins A and C (SPEA SPEC) of Streptococcus pyogenes belong to the family mitogenic toxins which staphylococcal enterotoxins are prototypes. erythrogenic toxin B (SPEB) is a proteinase precursor. All SPE have been reported be superantigens. Here we analyzed human T cell response these toxins. We used highly purified preparations SPEA, SPEB, SPEC from different S. strains. These were apparently homogenous in SDS-PAGE, IEF, HPLC. In addition, recombinant SPEA...
Metal borides, a class of materials intensively used in industry as superconductors, magnetic materials, or hot cathodes, remain largely unexplored at the nanoscale mainly due to difficulty synthesizing single-phase nanocrystals. Recent works have shown that synthetic methods lower temperatures (<400 °C) yield amorphous polydisperse nanoparticles, while phase purity is an issue higher temperatures. Among all metal-rich nickel borides (NixB) could be potential catalyst for broad range...
Abstract Solid polymer electrolytes (SPEs) offer inherent advantages for battery applications, such as high safety and excellent processability, but their practical use is limited by challenges like low ionic conductivity, subpar mechanical properties, instability of the electrode/electrolyte interface. Here, novel SPEs are developed embedding 2D MXenes decorated at surface with methoxypolyethylene glycol chains into poly(vinylidene fluoride)‐hexafluoropropylene matrices, enhanced...
Two-dimensional (2D) transition metal dichalcogenides have emerged as a promising platform for next-generation optoelectronic and spintronic devices. Mechanical exfoliation using adhesive tape remains the dominant method preparing 2D materials of highest quality, including dichalcogenides, but always results in small-sized flakes. This limitation poses significant challenge investigations applications where large scale flakes are needed. To overcome these constraints, we explored preparation...
The effects of nitrosyl fluoride (FNO) gas treatment on the surface GaN(0001) and its interface with sputtered Pt were investigated by hard x-ray photoelectron spectroscopy (HAXPES). Annealing GaN Pt/GaN samples in an FNO atmosphere resulted appearance prominent F 1s peaks HAXPES spectra, indicating efficient formation Ga–Fx bonding states not only bare-GaN but also Pt/GaN, even when was performed after deposition. In addition, chemical shifts Ga 2p3/2 N corresponded to a Fermi level shift...
To enable green hydrogen production through alkaline water electrolysis, it is crucial to enhance the activity of nickel electrocatalysts towards oxygen evolution reaction (OER), while preserving high stability. Here,...
Two-dimensional (2D) transition metal dichalcogenides have emerged as a promising platform for next-generation optoelectronic and spintronic devices. Mechanical exfoliation using adhesive tape remains the dominant method preparing 2D materials of highest quality, including dichalcogenides, but always results in small-sized flakes. This limitation poses significant challenge investigations applications where large scale flakes are needed. To overcome these constraints, we explored preparation...
The superantigenic properties of M protein type 5 Streptococcus pyogenes have been implicated as an important pathogenicity factor in streptococcal autoimmune diseases. Here we show that after a single purification step by affinity chromatography on immobilized albumin or fibrinogen, has no mitogenic activity for T cells. We demonstrate the superantigenicity proteins and 1 is due to contamination with highly potent pyrogenic exotoxins S. range 0.1 0.01%. These results raise general caveat...
Na has deliberately been incorporated into Cu(In,Ga)Se2 (“CIGSe”) chalcopyrite thin-film solar cell absorbers deposited on Mo-coated polyimide flexible substrates by adding differently thick layers of NaF in-between CIGSe absorber and Mo back contact. The impact the chemical electronic surface structure with various Cu-contents at comparatively low temperature (420 °C) studied using x-ray photoelectron excited Auger electron spectroscopy. We observe a higher content for Cu-richer samples can...
The chemical structure of the interface between silicon thin films and transparent conductive oxide ZnO:Al has been investigated by hard x-ray photoelectron spectroscopy. By varying excitation energy 2010 8040 eV, we were able to probe Si/ZnO buried below 12 nm Si. This allowed for identification changes induced solid phase crystallization (SPC). Based on in-situ SPC annealing experiments, find clear indications that formation Si–O bonds takes place at expense Zn–O bonds. Hence, acts as...
Abstract Poly(3,4‐ethylenedioxy thiophene):poly(styrenesulfonate) (PEDOT:PSS) exhibits valuable characteristics concerning stability, green‐processing, flexibility, high electrical conductivity, and ease of property modulation, qualifying it as one the most promising p‐type organic conductors for thermoelectric (TE) applications. While blending with inorganic counterparts is considered a good strategy to further improve polymeric TE properties, only few attempts succeed so far due...
Streptococcal proteinase precursor (SPP) is a zymogen secreted by Streptococcus pyogenes that becomes activated to cysteine proteinase. SPP has been shown be immunologically identical streptococcal erythrogenic toxin B (SPE B), and sequence comparison high degree of homology between the two proteins. In this study, we have constructed speB mutant strain S. insertional inactivation. An internal fragment cloned gene in plasmid pCR1000 was replaced with an erythromycin resistance determinant,...
This study describes the potential and challenges involved with use of wide bandgap kesterite absorbers in tandem solar cells.
The superantigenic streptococcal erythrogenic toxins A and C (ETA/SPEA ETC/SPEC) elicit the production by human peripheral blood mononuclear cells of substantial amounts Th1-derived cytokines (interleukin-2 [IL-2] gamma interferon) as well anti-inflammatory (IL-10 IL-1 receptor antagonist). In contrast, very low levels IL-4 no alpha interferon were induced. these after stimulation with Streptococcus pyogenes heat-killed bacteria lipopolysaccharide from gram negative differed qualitatively...
A sustainable catalyst development utilizing earth-abundant iron oxide (FeO x ) nanoparticles for photochemical oxygen reduction to hydrogen peroxide (H 2 O was achieved, generating a valuable green oxidant and future energy carrier.
Time-dependent dielectric breakdown (TDDB) data on 210-AA oxide films made with a 1.25- mu m CMOS process using large-area test capacitors (0.3 cm/sup 2/) are presented. Stress temperatures of 60 degrees C and 150 were used while the electric field stress was varied from near-operation conditions (3 MV/cm) to highly accelerated (8 MV/cm). Approximately 14000 have been aged. In an attempt model functionality, abrupt change in standard deviation (sigma) log-normal failure distribution observed...