A5051676400- Genetic Associations and Epidemiology
- RNA Research and Splicing
- Racial and Ethnic Identity Research
- Adolescent and Pediatric Healthcare
- Health Policy Implementation Science
- RNA and protein synthesis mechanisms
- Religion, Spirituality, and Psychology
- Mental Health Treatment and Access
- Mental Health and Psychiatry
- Ethics in Clinical Research
- Mental Health and Patient Involvement
University of Cape Town
2015-2020
Groote Schuur Hospital
2015-2017
Africa, the ancestral home of all modern humans, is most informative continent for understanding human genome and its contribution to complex disease. To better understand genetics schizophrenia, we studied illness in Xhosa population South recruiting 909 cases 917 age-, gender-, residence-matched controls. Individuals with schizophrenia were significantly more likely than controls harbor private, severely damaging mutations genes that are critical synaptic function, including neural...
Although the relationship between cultural beliefs and schizophrenia has received some attention, relatively little work emerged from African contexts. In this study we draw a sample of South Xhosa people with schizophrenia, exploring their explanations illness. The purpose article is to examine context content delusions.
Community engagement within biomedical research is broadly defined as a collaborative relationship between team and group of individuals targeted for research. A Advisory Board (CAB) one mechanism engaging the community. Within genomics CABs may be particularly relevant due to potential implications findings drawn from individual participants on larger communities they represent. such research, seek meet instrumental goals protecting their community research-related risks, well intrinsic...