Early life exposure to adverse environments, and maternal stress in particular, has been shown increase risk for metabolic diseases neurobehavioral disorders. While many studies have examined the hypothalamic-pituitary-adrenal axis (HPA axis) as primary mechanism behind these relationships, emerging research on brain-gut suggests that microbiome may play a role. In this study, we tested relationships among precarity HPA dysregulation during peripartum period, infant gut composition, functioning.

Digital health is increasingly used to meet the needs of perinatal people, with estimates pregnancy-related internet use ranging from 90% 97% pregnant people. As digital takes on greater importance during period, it essential that providers and developers content understand why people these resources features enhance their experience. However, gaps remain in understanding most helpful how platforms are navigated. Learning directly about will help ensure alignment between available content.

Abstract Background Admission to the neonatal intensive care unit (NICU) is costly and has been associated with financial emotional stress among families. Digital health may be well equipped impact modifiable factors that contribute NICU admission rates. Objective The aim of study investigate how use a comprehensive prenatal digital platform gestational age at birth mechanisms reduce risk NICU. Methods Data were extracted from 3326 users who enrolled in between January 2020 May 2022....

Global increases in caesarean deliveries are exposing more infants to perinatal environments that evolutionarily novel and potentially increasing their risks for inflammatory conditions. Yet, the pathways linking caesareans later health outcomes not well understood, particularly dual burden contexts. We test two of hypothesized pathways, altered immune function gut microbiota, which may link delivery mode whether these associations persist when controlling postnatal nutritional pathogenic...

Background Almost one-third of pregnant people visit the emergency room during pregnancy. Although some care is necessary, gaps in patient education and inaccessibility preventive services have been identified as key reasons for high-cost, low-value Digital platforms present a promising solution providing resources to supplement routine prenatal care, thereby reducing use in-person services. Objective This study aimed describe relationship between Maven avoidance (emergency or office visits)...

Abstract Background Ecuador’s cesarean delivery rate far exceeds that recommended by the Pan American Health Organization (PAHO) and World (WHO). Using data from three iterations of nationally representative, population‐based survey Encuesta Nacional de Salud y Nutrición (ENSANUT/ENDEMAIN), spanning 23 years, this study examines women’s mode outcomes sociodemographic characteristics hospital type (private, public, social security) in light major health care reform over past two decades....

Social determinants of health significantly affect outcomes, yet are infrequently addressed in prenatal care. This study aimed to improve the efficiency and experience addressing social needs pregnancy through: (1) testing a digital short-form screening tool; (2) characterizing pregnant people's preferences for management. We developed tool from PRAPARE (Protocol Responding Assessing Patients' Assets, Risks, Experiences), survey query patients' needs. Instruments were administered online...

Objectives Digital health solutions have the potential to improve maternal mental care. The objective of this study is determine if utilization a digital platform, Maven, associated with improved management among peripartum people history disorders and which components associate outcomes. Methods Participants in retrospective cohort analysis (n = 1561) accessed Maven as an employer‐sponsored benefit enrolled during their pregnancy delivered from January 2020 through September 2022. completed...

Objective Given the complex nature of preterm birth, interventions to reduce rates birth should be multifaceted. This analysis aimed explore association between duration using Maven, a digital health platform for women's and family health, odds birth. Methods Data came from 3326 pregnant, nulliparous Maven users who enrolled in during their pregnancy January 2020 September 2022. Chi-square Fisher's exact tests compared characteristics developed gestational conditions did not. retrospective...

Abstract Background Women's preferred mode of birth during pregnancy is predictive their actual birth. Digital prenatal care services are a promising method for educating women on to reduce elective cesareans. This study aimed evaluate the influence digital health association between preference and Methods Data come from 5409 pregnant enrolled in platform women's family health. Multi‐trajectory modeling identified trajectories usage throughout pregnancy. Adjusted logistic regression models...

We examined how utilization of Maven, a digital healthcare platform that provides virtual prenatal services, is associated with improvements in perceived management anxiety and depression during pregnancy, medical knowledge support may influence this association.In retrospective study we used adjusted logistic regression to examine the relationship between use pregnancy mental health management, affected by user-reported feeling supported platform. Effects were evaluated separately among...

To identify trajectories of prenatal digital service utilization across pregnancy and examine their associations with outcomes. Data were extracted from 5409 pregnant people enrolled in Maven, a comprehensive platform for women's family health, between January 1, 2020, May 27, 2022. Multitrajectory modeling used data (eg, articles read, classes attended, appointments providers) at each trimester to use pregnancy. Multinomial logistic regression models tested the user-reported education,...

Abstract Objective The objective of this study was to understand the use supplemental digital prenatal services by race and ethnicity among pregnant people utilizing a comprehensive, employer‐sponsored health platform. Materials Methods We conducted retrospective cohort enrolled in platform, assessing utilization app‐based ethnicity. Care included three categories: asynchronous (e.g., article reads, videos); interactions with care advocate, trained navigator; provider messages visits medical...

Abstract Background The transition to parenthood is a period of major stressors and increased risk anxiety for all parents. Though rates perinatal are similar among women (4%-25%) men (3%-25%), research on nonbirthing partners remains limited. Objective We aimed examine whether demographic characteristics or digital support preferences differed with compared without self-reported high parenthood-related anxiety. Methods In this large cross-sectional study using health platform during their...

ABSTRACT Introduction Inflammation is a marker of immune activation. may have an effect on both ovarian function and luteal function, essential to pregnancy. High inflammation also signal dysregulated processes within the ovary, which could be in part measured through Anti‐Müllerian hormone, follicle‐stimulating inhibin B levels. Objective To determine relationship between inflammation, by C‐reactive protein, three biomarkers during early follicular phase: B. Methods Secondary...