Sign Language is the most natural and expressive way for hearing impaired. This paper presents a methodology which recognizes Indian (ISL) translates into normal text. The consists of three stages, namely training phase, testing phase recognition phase. Combinational parameters Hu invariant moment structural shape descriptors are created to form new feature vector recognize sign. A multi-class Support Vector Machine (MSVM) used recognizing signs ISL. effectiveness proposed method validated...

Posthumanism has emerged as a crucial conceptual framework in the field of literature. While future remains uncertain, humanity's innate curiosity about its relationship with nature, animals and non-living entities always been core topic discussion. The ethical principles put forth by posthumanism are significant today’s rapidly evolving world, emphasizing interconnectedness all beings, whether or not people acknowledge this bond. Hungry Tide Amitav Ghosh uses theory to critique...

Skeletal muscle diseases like myopathies and muscular dystrophies present significant clinical challenges with few effective treatments. To better understand disease mechanisms accelerate therapy development, robust in vitro models are needed. Extrusion- light-based bioprinting offer precise fabrication of tissue-like constructs, but creating bioinks that support cell function remains difficult. Here, we report a novel bioink which taurine is first methacrylated substituting its NH2 groups...

Suffix tree is one of the most important data structures in string algorithms and biological sequence analysis. Unfortunately, when it comes to implementing those applying them real genomic sequences, often main memory size becomes bottleneck. This easily explained by fact that while a DNA length n from alphabet Σ = { A , C G T } can be stored log |Σ| 2 bits, its suffix occupies O ( ) bits. In practice, difference reaches factor 50. We report on an implementation compressed very recently...

Abstract Scaffolds play an essential role in bone healing by providing temporary structural support to the native tissue and hosting cells. To this end, several biomaterials manufacturing methods have been proposed. Among biomaterials, bio-active glasses attractive properties as a scaffold material for repair. Simultaneously, additive (AM) techniques attracted significant attention owing their capability of fabricating complex patient-specific scaffolds. Accordingly, borosilicate glass...

Conventional three-dimensional (3D)-printed hydroxyapatite (HA)-based constructs have limited utility in bone tissue engineering due to their poor mechanical properties, elevated risk of microbial infection, and pore interconnectivity. 3D printing complex multiple components fabricate fully interconnected scaffolds is a challenging task; here, this work, we developed procedure for fabrication printable ink systems containing multinanomaterials, i.e., HAACZ (containing 1 wt % Ag, 4 CeO2, 6...

Abstract Graphene-reinforced bioactive glass scaffolds have gained significant attention in the field of bone tissue engineering due to their unique combination mechanical strength, bioactivity, and electrical conductivity. Additive manufacturing techniques, such as 3D printing, provide a versatile platform for fabricating these with precise control over architecture composition. Consequently, this work, we fabricated graphene oxide (GO)-reinforced 13-93B1 scaffold using direct ink writing...

45S5 Bioglass® has been used quite extensively in the form of particulate as synthetic bone graft. However, glass certain limitations such difficulty sintering and slow partial conversion to hydroxy carbonated apatite. In pursuit overcoming these limitations, bioactive glasses (13-93B1) containing increased amount B₂O₃ by replacement SiO₂ have prepared using sol-gel technique this study. Since are brittle nature, therefore, they unsuitable for load bearing sites. Consequently, 3D porous...

Efficient utilization of human resources is imperative for information technology (IT) service businesses that continually manage the assignment and movement practitioners to or between projects. These organizations constantly strive balance many objectives multiple stakeholders in order minimize idle while aiming increase revenue from new project opportunities, as well improve quality assigned each project. However, these various conflict, so we can only hope achieve an aggregated form...

Vascularization is an indispensable requirement for fabricating large solid tissues and organs. The natural vasculature derived from medical imaging modalities organs are highly complex convoluted. However, the present bioprinting capabilities limit fabrication of such vascular networks. Simplified bioprinted networks, on other hand, lack capability to sustain tissues. This work proposes a generalized adaptable numerical model design by utilizing tissue/organ anatomy. Starting with...

Abstract As the aging population grows, need to regenerate non-self-repairing tissues becomes increasingly crucial for enhancing our quality of life. Tissue engineering offers a promising solution, particularly in recreating intricate networks blood vessels tissue vitality. These rely on effective nutrient and oxygen circulation, with an optimal diffusion range 100–200 µm. Yet, crafting vascularized vitro remains significant challenge. This study addresses challenge by using GelMA-based...

In this study, carbon nanotube (CNT) reinforced functionally graded bioactive glass scaffolds have been fabricated using additive manufacturing technique. Sol-gel method was used for the synthesis of glass. For ink preparation, Pluronic F-127 as an carrier. The CNT-reinforced were coated with polymer polycaprolactone (PCL) dip-coating to improve their properties further by sealing micro-cracks. CNT- reinforcement and coating resulted in improvement compressive strength additively...

Abstract Electrical conductivity is a crucial requirement of matrices for developing engineered neural tissues. A conductive matrix not only supports cell growth but also provides potential to stimulate the cells. However, electrically often require inclusion synthetic polymers, nanomaterials and large number ionic species. While enhancing electrical conductivity, properties like transparency, mechanical stiffness biocompatibility are compromised which can render resulting partially suitable...

In this work, the effect of varying content B₂O₃ with respect to SiO₂ on mechanical and bioactivity properties have been evaluated for borosilicate bioactive glasses containing SiO₂, B₂O₃, CaO P₂O5. The synthesized using sol-gel technique. were characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy Field Emission Scanning electron microscopy (FESEM). These fabricated as scaffolds polymer foam replication method. Subsequently, in vitro evaluation glass was...

In this work, functionally graded scaffolds of nanofiber reinforced bioactive glass have been fabricated using additive manufacturing technique. The was synthesized sol-gel method. Pluronic F-127 used as ink carrier for fabricating the scaffolds. nanofibers are uniformly dispersed in matrix. inclusion showed 94% enhancement compressive strength demonstrating their potential bone tissue engineering applications.

Abstract This study aims to predict mechanical properties of scaffolds made bioactive glass-carbon nanotube (CNT) composite through finite element analysis (FEA) and their permeability using computational fluid dynamics (CFD) simulations. We start with constructing a three-dimensional model for the complete scaffold cleaned/denoised images obtained from microcomputed tomography. To save effort, representative volume (RVE) is carved out this such that geometric like porosity tortuosity are...