- Organic Electronics and Photovoltaics
- Conducting polymers and applications
- Spectroscopy and Quantum Chemical Studies
- Advanced Proteomics Techniques and Applications
- Quantum Dots Synthesis And Properties
- Perovskite Materials and Applications
- Clusterin in disease pathology
- Glycosylation and Glycoproteins Research
- Cold Atom Physics and Bose-Einstein Condensates
- Cancer Genomics and Diagnostics
- Monoclonal and Polyclonal Antibodies Research
- Semiconductor Quantum Structures and Devices
- Nonlinear Photonic Systems
- Laser-induced spectroscopy and plasma
- Caveolin-1 and cellular processes
- Heat shock proteins research
- Nanotechnology research and applications
- Advanced Chemical Physics Studies
- Protein purification and stability
- Quantum, superfluid, helium dynamics
- Experimental Learning in Engineering
- Laser-Plasma Interactions and Diagnostics
- Molecular Biology Techniques and Applications
- Molecular Junctions and Nanostructures
- Strong Light-Matter Interactions
Rochester Institute of Technology
1989-2024
Womack Army Medical Center
2019
Walter Reed National Military Medical Center
2017-2018
Uniformed Services University of the Health Sciences
2018
Johns Hopkins Hospital
2018
National Institutes of Health
2018
National Cancer Institute
2018
Center for Cancer Research
2018
Valid International (United Kingdom)
2018
United States Department of Defense
2018
We present a unified quantitative explanation of the temperature dependence drift mobilities photoinjected electrons in naphthalene for all directions and temperatures. The theory proposed is based on polaronic description charge carriers calculational scheme employs site-local states. Excellent agreement experiment occurs known reasonable parameters.
Abstract Background New biomarkers that replace or are used in conjunction with the current ovarian cancer diagnostic antigen, CA125, needed for detection of presurgical setting, as well disease recurrence. We previously demonstrated upregulation leucine-rich alpha-2-glycoprotein-1 (LRG1) sera patients compared to healthy women using quantitative mass spectrometry. Methods LRG1 was quantified by ELISA serum from two relatively large cohorts and benign gynecological disease. The expression...
PURPOSE CD44 is a hyaluronic acid receptor that exists as standard 90-kd form (CD44S) well several variant isoforms produced through alternative splicing. Expression of variants associated with clinically aggressive behavior in some human tumors. The purpose the present study to define expression ovarian cancer and investigate whether these molecules adverse prognosis. MATERIALS AND METHODS Six specimens normal surface epithelium (NOSE) 31 separate cases newly diagnosed were studied by...
Abstract Ovarian cancer is the fifth leading cause of death for women in US, yet survival rates are over 90% when it diagnosed at an early stage, highlighting need biomarkers detection. To enhance discovery tumor‐specific proteins that could represent novel serum ovarian cancer, we depleted highly abundant which can mask detection present low concentrations. Three commercial immunoaffinity columns were used parallel to deplete from 60 patients with serous carcinoma and non‐cancer controls....
We sought to investigate the expression levels of S100A1 in ovarian cancer cell lines and tissues correlate with subtype, stage, grade, relapse-free survival. messenger RNA protein were up-regulated tumors compared normal by gene microarray analysis, reverse transcriptase-polymerase chain reaction, quantitative Western immunoblotting. In study, 63.7% serous, 21.2% clear cell, 11.2% endometrioid, 3% mucinous (1/31) cancers S100A1+ immunohistochemical staining tissue microarrays (n = 500)....
Ovarian cancer is the most lethal gynecologic malignancy, with majority of cases diagnosed at an advanced stage when treatments are less successful. Novel serum protein markers needed to detect ovarian in its earliest stage; detected early, survival rates over 90%. The identification new biomarkers hindered by presence a small number highly abundant proteins that comprise approximately 95% total protein. In this study, we used pooled depleted reduce dynamic range proteins, and thereby...
We present exact analytical solutions of the discrete nonlinear Schro\ifmmode\ddot\else\textasciidieresis\fi{}dinger equation for N-site systems by generalizing methods employed previously quantum dimer and trimer. The transition from localized to delocalized states is markedly different that in dimer. A transition, which there no analog, occurs an initial excitation partially over a group sites found be these same or depending on strength nonlinearity asymmetry lattice.
Claudin 4 is a cellular adhesion molecule that frequently overexpressed in ovarian cancer and other epithelial cancers. In this study, we sought to determine whether the expression of claudin associated with outcome patients may be involved tumor progression. We examined tissues cell lines, as well by immunohistochemical staining tissue microarrays (TMAs; n = 500), spheroids present patients’ ascites, formed vitro. was expressed nearly 70% differentially across subtypes, lowest clear...
We report the first observation of ESR negative ions in liquid $^{3}\mathrm{He}$. The signals exhibit pressure-dependent integrated signal intensity and line shape. These data are tentatively interpreted by considering hyperfine coupling bound electron with surrounding $^{3}\mathrm{He}$ nuclear moments.
Solution-processed bulk heterojunction organic solar cells fabricated with 1,3-bis[4-(N,N-diisopentylamino)-2,6-dihydroxyphenyl]squaraine and phenyl-C61-butyric acid methyl ester were found to exhibit unexpectedly low external quantum efficiency in the squaraine regions upon annealing. X-ray diffraction (XRD), spectral response, time-resolved microwave absorption all used characterize materials devices prepared from them. An explanation for drop is proposed using Marcus–Hush theory tie...
We have theoretically analyzed the potential efficiency improvement to multi-junction solar cell efficiencies which are available through incorporation of quantum dot using detailed balance calculations. also experimentally investigated Stranski-Krastanov growth self-organized InAs dots and arrays on lattice-matched GaAs by metallorganic vapor phase epitaxy (MOVPE). The morphology were as a function their parameters atomic force microscopy (AFM). Photoluminescence optical absorption...
An intermediate-bandwidth theory of charge-carrier mobility is developed with a focus on finite-band effects and scattering by phonons. Wide-band behavior recovered as limit. Two applications the are discussed: in one dip predicted temperature dependence mobility, other recently reported observations ultrapure organic crystals addressed.
The quantum mechanical energy-mismatched two-state system with cubic nonlinearity in its governing equation is surprisingly rich dynamics and has relevance to a number of subdisciplines physics ranging from polaron phenomena Bose–Einstein condensation. We review some them that have been discussed recently describe new results not, pointing out their possible experiments.
Abstract Exact analytical solutions of the discrete nonlinear Schrödinger equation for three‐site systems are presented by generalizing methods employed previously quantum dimer. The transition from localized to delocalized states is markedly different that in
A simple electronic correlator for two-time photoelectric correlation measurements has been developed. It functions by registering the distribution of time intervals between pairs pulses. Its basic elements are a clock that is started first pulse and used to digitize intervals, pair fast counters counting subsequent pulses, set data registers. The pulses directed one or other counter alternately at regular intervals. operation described tested randomly modulated light source.
A Boltzmann-equation analysis of low-temperature ($T<100$ K) electron drift mobilities in naphthalene reveals that acoustic-phonon scattering electrons extended energyband states provides a quantitative interpretation the temperature dependence these mobilities.
This paper reports the developments of modular courses and curricula in nano- microelectromechanical systems (MEMS). We design a Nano Science, Engineering Technology (NanoSET) course as well MEMS curriculum. The curriculum consists three courses, e.g., Design, Fabrication Evaluation. role implication quantum mechanics, nanotechnology, microscopic systems, molecular engineering, microelectronics are examined. discuss integration physics, electronics, microsystems nanotechnology engineering...
State of the art photovoltaics exhibiting conversion efficiency in excess 30% (1-sun) utilize epitaxially grown multijunction III-V materials. Increasing photovoltaic is critically important to space power, and more recently, terrestrial concentrator PV communities The use nanostructured materials within devices can enable improved efficiency, potentially Shockley-Queisser limit. addition nanostructures such as quantum dots (QDs) allows one extend absorption spectrum solar cell "tune"...
Using basic fundamentals, engineering and science encompass continuously evolving technologies. In response to these changes emerging opportunities, curricula evolve revisiting program objectives, goals outcomes. By integrating various disciplines tools, nanotechnology-centered provides a multidisciplinary approach needed meet societal challenges industry needs. Extensive advances in biotechnology, electronics, energy sources, information technology nanosystems, have brought new academia. As...
Intracardiac heterotopic liver is a very rare entity. The most unique aspect of this entity the increased carcinogenic potential tissue. This condition must be considered when assessing an intracardiac mass along with more common differential diagnoses such as neoplasms, thrombi, and vegetations. In report, we present case patient who presented to cardiac surgery for elective excision right atrial that was determined accessory lobe. We discuss diagnostic challenges, clinical management,...
In this paper, we discuss coherent atomic oscillations between two weakly coupled Bose–Einstein condensates that are energetically different. The weak link is notionally provided by a laser barrier in (possibly asymmetric) multi-well trap or Raman coupling different hyperfine levels. resultant boson Josephson junction dynamics described double-well nonlinear Gross–Pitaevskii equation. On the basis of new set Jacobian elliptic function solutions, describe period as well associated quantities...