- Advanced Radiotherapy Techniques
- Radiomics and Machine Learning in Medical Imaging
- Antenna Design and Analysis
- Advanced Antenna and Metasurface Technologies
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Microwave Engineering and Waveguides
- Acoustic Wave Resonator Technologies
- Radiation Therapy and Dosimetry
- Advanced Vision and Imaging
- Head and Neck Cancer Studies
- Advanced Optical Sensing Technologies
- Glioma Diagnosis and Treatment
- Lymphatic System and Diseases
- AI in cancer detection
- Artificial Intelligence in Healthcare and Education
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced MIMO Systems Optimization
- Advanced MEMS and NEMS Technologies
- Neutropenia and Cancer Infections
- Radiation Detection and Scintillator Technologies
- Bluetooth and Wireless Communication Technologies
- Systemic Sclerosis and Related Diseases
- Management of metastatic bone disease
- DNA Repair Mechanisms
Northwestern University
2021-2024
Northwestern Memorial Hospital
2024
Siemens Healthcare (United States)
2023
University Hospitals Birmingham NHS Foundation Trust
2023
Digital Health Cooperative Research Centre
2022
Digital China Health (China)
2022
CancerCare Manitoba
2013-2019
University of Manitoba
2013-2019
University of Pittsburgh
2018-2019
UPMC Hillman Cancer Center
2018-2019
Artificial intelligence (AI) large language models (LLMs) demonstrate potential in simulating human-like dialogue. Their efficacy accurate patient-clinician communication within radiation oncology has yet to be explored.
DNA-damaging chemotherapy and radiation therapy are integrated into the treatment paradigm of majority cancer patients. Recently, immunotherapy that targets immunosuppressive interaction between programmed death 1 (PD-1) its ligand PD-L1 has been approved for malignancies including non–small cell lung cancer, melanoma, head neck squamous carcinoma. ATR is a DNA damage–signaling kinase activated at damaged replication forks, inhibitors potentiate cytotoxicity chemotherapies. We show here...
Abstract Identification of isocitrate dehydrogenase ( IDH )-mutant glioma patients at high risk early progression is critical for radiotherapy treatment planning. Currently tools to stratify are lacking. We sought identify a combination molecular markers that could be used who may have greater need adjuvant radiation therapy machine learning technology. 507 WHO Grade 2 and 3 cases from The Cancer Genome Atlas, 1309 AACR GENIE v13.0 datasets were studied genetic disparities between IDH1...
The accurate prediction of intrafraction lung tumor motion is required to compensate for system latency in image-guided adaptive radiotherapy systems. goal this study was identify an optimal model that has a short learning period so and adaptation can commence soon after treatment begins, requires minimal reoptimization individual patients. Specifically, the feasibility predicting position using combination generalized (i.e., averaged) neural network, optimized historical patient data...
Purpose The International Atomic Energy Agency ( IAEA ) and the American Association of Physicists in Medicine AAPM have jointly published a new code practice (CoP), TRS 483, for dosimetry small static photon fields used external beam radiotherapy. It gave recommendations on how to perform reference nonstandard machine‐specific (msr) measure field output factors fields. purpose this work was dosimetric evaluation given CoP. Methods All measurements were done Varian TrueBeam™ ST x linear...
Purpose A new type of linear accelerator (linac) was recently introduced into the market by a major manufacturer. Our institution is one early users this preassembled and preconfigured dual‐layer multileaf collimator ( MLC ), ring‐gantry linac — Halcyon™ (1st version). We performed set full acceptance testing commissioning ATC ) measurements for three Halcyon machines compared measured data with standard beam model provided The were following guidelines given in different AAPM protocols as...
A novel square microstrip patch antenna with a single-patch and single-layer structure is demonstrated. By incorporating an air-filled substrate thickness of around 0.08 /spl lambda//sub 1/ having one edge shorted three shorting-pins, impedance bandwidth (return loss <-10dB) 67.5% from 3.62 GHz to 7.32 obtained for this probe-fed compact broadband antenna. The details design, analyses, measurement results are presented discussed.
This paper investigates the feasibility and accuracy of using a computer vision algorithm electronic portal images to track motion tumour-like target from breathing phantom. A multi-resolution optical flow that incorporates weighting based on differences between frames was used obtain set vectors corresponding two frames. global value representing average obtained by computing weighted mean vectors. The tracking as function rate visibility investigated. Synthetic with different...
Head and neck lymphedema (HNL) following radiation therapy for head cancer (HNC) causes patient morbidity. Predicting individual patients' risk of HNL after treatment is challenging. We aimed to identify the demographic, disease-related, treatment-related factors associated with external internal HNC definitive or adjuvant therapy.
The design and development of a smart wireless system for remote reading passive surface acoustic wave (SAW) sensor is presented in this paper. SAW lithium niobate wafer with an inter-digital transducer (IDT) reflectors, which inductively coupled to microstrip meander antenna (ICMA). special FM radar, transmits receives electromagnetic signals. transmitted signal picked up by the ICMA subsequently, converts into LiNbO3 through IDTs. These SAWs are reflected back IDTs converted returned radar...
The beam scanning characteristics of a two-element array utilising ferroelectric phase shifter are presented for the first time. Applying DC voltage across material changes velocity input signal, scan 26° being achieved. S11 performance and radiation patterns at two frequencies presented.
Various techniques of deep inspiration breath hold (DIBH) have been used to mitigate the likelihood and risk exposing heart, an organ-at-risk (OAR) for unintended radiation during left breast radiotherapy. However, issues reproducibility these warrant further investigation into feasibility detecting intrusion OAR treatment field intra-fractional delivery. The increase high-dose, low-fraction radiotherapy treatments makes it important immediately adapt once is detected in field. This...
A novel antenna in the shape of a Maltese cross has been developed for GPS satellite and DCS1800 personal communication system application. This exhibits good circular polarization (axial ratio <2 dB) impedance performance over bandwidth wide enough to cover frequency band reception. The addition an adjustable clamp tapering radiating elements improved overall design. gain this sufficiently high compensate power loss due mismatch reception linearly polarized GSM/DCS1800 signal. modular...
PURPOSE We developed a deep neural network that queries the lung computed tomography–derived feature space to identify radiation sensitivity parameters can predict treatment failures and hence guide individualization of radiotherapy dose. In this article, we examine transportability model across health systems. METHODS This multicenter cohort-based registry included 1,120 patients with cancer in treated stereotactic body radiotherapy. Pretherapy tomography images from internal study cohort...
Deep learning (DL) models that use medical images to predict clinical outcomes are poised for translation. For tumors reside in organs move, however, the impact of motion (i.e., degenerated object appearance or blur) on DL model accuracy remains unclear. We examine tumor an image-based framework predicts local failure risk after lung stereotactic body radiotherapy (SBRT).We input pre-therapy free breathing (FB) computed tomography (CT) from 849 patients treated with SBRT into a multitask...
Three-dimensional (3D) full-wave analysis and design of bandpass frequency-selective surfaces (FSSs) is presented. By using the unique features a unit cell periodic boundary conditions, infinite FSSs can be simulated. Wave propagation through FSSs, which otherwise difficult to quantify, visualised by commercial CAD tool. The creation simulation model, interpretation outcome, comparison with experimental results are presented for square-slot square-loop-slot band-pass FSS. © 2004 Wiley...
This paper investigates the feasibility and accuracy of tracking motion an intruding organ-at-risk (OAR) at edges a treatment field using local optical flow analysis electronic portal images. An OAR was simulated by modifying images obtained irradiating programmable phantom's lung tumour. A rectangular aperture assumed beam's eye view (BEV) were partitioned into clusters/grids according to width multi-leaf collimators (MLC). The velocities calculated in these clusters analysed. velocity...
A mechanical counter-steering prototype which includes a slider system was developed to evaluate tracking and prediction algorithms used for tumor motion compensation. The compensation aims maintain stationary with respect the radiation beam. Motion performed an optical flow algorithm. Three techniques of reference image registration were evaluated. To compensate latency, neural network sliding window learning scheme predict positon. mean (position) error -0.05 ± 0.04 mm obtained using...
Abstract A bow‐tie element with an orthogonal feed arrangement has been developed to conform the shape of a handheld device. An improved method antenna was realised, which includes modification printed Roberts balun stubs provide exact location and broadening sharp edges at positions elements. wideband (maximum bandwidth 22.8%) dual band characteristics will be shown. © 2002 Wiley Periodicals, Inc. Microwave Opt Technol Lett 35: 255–257, 2002; Published online in InterScience...