A5051554295- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Carbohydrate Chemistry and Synthesis
- Cancer therapeutics and mechanisms
- Bacterial biofilms and quorum sensing
- Antimicrobial agents and applications
- Cystic Fibrosis Research Advances
- Phenothiazines and Benzothiazines Synthesis and Activities
- Research on scale insects
- Chemical Reactions and Mechanisms
- Antifungal resistance and susceptibility
- Synthesis and Biological Evaluation
- Fungal Infections and Studies
- Synthesis and Catalytic Reactions
- Helminth infection and control
- Coccidia and coccidiosis research
- Invertebrate Immune Response Mechanisms
- Bioactive Compounds and Antitumor Agents
- Bacterial Infections and Vaccines
- Quinazolinone synthesis and applications
- Aquaculture disease management and microbiota
- Antimicrobial Peptides and Activities
- Streptococcal Infections and Treatments
- Peptidase Inhibition and Analysis
University of Antwerp
2016-2021
Norwegian University of Life Sciences
2015
It was recently proposed that bactericidal antibiotics, besides through specific drug-target interactions, kill bacteria by a common mechanism involving the production of reactive oxygen species (ROS). However, this hydroxyl radicals has become subject lot debate. Since contribution ROS to antibiotic mediated killing most likely depends on conditions, differences in experimental procedures are expected be at basis conflicting results. In present study different methods (ROS stainings,...
Streptococcus pneumoniae is the leading cause of bacterial pneumonia. Infection linked to high morbidity and mortality rates antibiotic resistance within this pathogen on rise. Therefore, there a need for novel antimicrobial therapies. To lower time costs drug discovery process, alternative in vivo models should be considered. As such, Galleria mellonella larvae can great value. The larval immunity consisting several types haemocytes remarkably similar human innate immune system....
Streptococcus pneumoniae, the most common cause of bacterial pneumonia, has developed a wide range virulence factors to evade immune system which polysaccharide capsule is important one. Formation this dependent on cps gene locus, but also involves other genes—like galU. The pyrophosphorylase encoded by galU plays role in UDP-glucose metabolism prokaryotes and required for biosynthesis capsular polysaccharides. In paper, effect mutation leading dysfunctional (UDPG:PP) vitro biofilm biomass,...
The occurrence and recurrence of mucosal biofilm-related
Pneumonia, of which Streptococcus pneumoniae is the most common causative agent, considered one three top leading causes death worldwide. As seen in other bacterial species, antimicrobial resistance on rise for this pathogen. Therefore, there a pressing need novel strategies to combat these infections. Recently, uridine diphosphate glucose pyrophosphorylase (UDPG:PP) has been put forward as potential drug target worth investigating. Moreover, earlier research demonstrated that streptococci...
During October 2013, 112 fecal samples were collected from wild blue wildebeest ( Connochaetes taurinus ) in Mikumi National Park, Tanzania, and examined for coccidians. Coccidia present 46% of samples, with shedding 60 to 18,000 oocysts per gram feces (median, 300; mean, 1,236). Five species, including 4 new identified. Oocysts Eimeria gorgonis 18% ellipsoidal, 23 × 18.4 μm, a length/width (L/W) ratio 1.3, oocyst wall 1-1.5 μm thick. Micropyle, residuum, polar granule absent. donaldi n. sp....