- Global Cancer Incidence and Screening
- Renal cell carcinoma treatment
- Intraocular Surgery and Lenses
- Renal and related cancers
- MRI in cancer diagnosis
- Breast Cancer Treatment Studies
- Liver Disease Diagnosis and Treatment
- Ophthalmology and Visual Impairment Studies
- Dialysis and Renal Disease Management
- Digital Radiography and Breast Imaging
- Pediatric Urology and Nephrology Studies
- Cancer survivorship and care
- Hepatocellular Carcinoma Treatment and Prognosis
- AI in cancer detection
- Corneal surgery and disorders
- Lung Cancer Diagnosis and Treatment
- Radiology practices and education
- Advanced Radiotherapy Techniques
- Blood Coagulation and Thrombosis Mechanisms
- Central Venous Catheters and Hemodialysis
- Epilepsy research and treatment
- Bladder and Urothelial Cancer Treatments
- Radiation Dose and Imaging
- Head and Neck Cancer Studies
- Pancreatic and Hepatic Oncology Research
Dalhousie University
2014-2024
Nova Scotia Health Authority
2015-2024
Queen Elizabeth II Health Sciences Centre
2009-2022
University of Toronto
2001-2017
University Health Network
2002-2017
Capital District Health Authority
2013
Public Health Ontario
2010-2011
Health Sciences Centre
2007-2009
Cancer Care Nova Scotia
2009
Princess Margaret Cancer Centre
2000-2008
PURPOSE: Breast cancer patients receiving chemotherapy have complained of difficulties in their ability to remember, think, and concentrate. This study assessed whether there are differences cognitive function between breast treated with standard-dose adjuvant compared healthy controls. PATIENTS AND METHODS: The High Sensitivity Cognitive Screen the Profile Mood States (POMS) were used assess mood a group 107 women. women consisted 31 (group A), 40 who had completed median 2 years earlier...
To derive and validate a simple predictive model for survival of patients with metastatic cancer attending palliative radiotherapy clinic.We described previously predicting referred using six prognostic factors: primary site, site metastases, Karnofsky performance score (KPS), the fatigue, appetite, shortness breath subscales from Edmonton Symptom Assessment Scale. Here we simplified to include only three KPS. Each factor was assigned value proportional its weight, weighted scores each...
PURPOSE: Benchmark analysis of patients with chronic myeloid leukemia (CML) alive for more than 10 years after allogeneic bone marrow transplantation (BMT) including data on disease status, reserve, long-term complications, and quality life (QOL). PATIENTS AND METHODS: Eighty-nine (46 in first phase, 43 advanced phase) received an BMT CML during the study period. Medical outcomes QOL were analyzed retrospectively. RESULTS: Twenty-eight (31.5%) 89 at included this analysis. Thirteen (46.4%)...
Background — Although the prenatal diagnosis of most fetal structural heart defects and dysrhythmias has been described, there is a paucity information about cardiomyopathies (CMs) in life. Methods Results —- To determine pathogenic mechanisms, hemodynamic findings, outcome CM, we reviewed echocardiograms perinatal histories 55 affected fetuses. Dilated CM was diagnosed 22 cases, including 2 with congenital infections, 5 familial 6 endocardial fibroelastosis related to maternal anti-Ro/La...
Summary An association has been reported between thrombotic events and the use of L-asparaginase (ASP) in children with acute lymphoblastic leukaemia (ALL). The mechanism for thrombosis is likely related to an acquired antithrombin deficiency. Since a primary prophylaxis using concentrates may prevent thrombosis, PARKAA (Prophylactic Antithrombin replacement kids ALL treated L-asparaginase) study was performed. objectives were determine if there trend efficacy safety treatment as assessed by...
At a metropolitan newspaper office in Canada with extensive video display terminal (VDT) use, researchers carried out survey (n = 1,007, 84% response) to establish baseline prevalence of work-related musculoskeletal disorders (WMSDs) and identify demographic, postural, task, psychosocial factors associated WMSD symptoms. One-fifth the respondents reported moderate or worse upper limb pain recurring at least monthly lasting more than week over previous year. Logistic regression showed that...
Risk and protective factors associated with disordered eating were examined among 363 girls (X age =12.9 years) in middle-level school. The variables included self-report ratings of competence the importance physical appearance social acceptance by peers, self-oriented socially prescribed perfectionism, negative events, parental support. In a multivariate regression analysis, low appearance, high acceptance, paternal support correlated significantly reports levels eating. influence on was...
To evaluate radiologists' knowledge of the appropriate management severe contrast material-induced allergic reactions by means a telephone survey.Institutional research ethics board approval was obtained. Following verbal consent, survey radiologists working in Canada's 13 English-speaking and U.S. university-affiliated radiology departments performed. Participants were selected using multistage sampling scheme simple random within departments. Given reaction case scenario, first asked their...
Artificial intelligence (AI) software in radiology is becoming increasingly prevalent and performance improving rapidly with new applications for given use cases being developed continuously, oftentimes development validation occurring parallel. Several guidelines have provided reporting standards publications of AI-based research medicine radiology. Yet, there an unmet need recommendations on the assessment AI before adoption after commercialization. As ecosystem continues to grow mature, a...
Summary Thromboembolism (TE) has recently been recognized as a clinical entity in children. Determining the characteristics of pediatric TE is an important first step dealing with this new disorder. The paper summarizes 1776 consecutive children systemic referred to 1-800-NO-CLOTS telephone consultation service. free service for clinicians managing TE. Patient information was collected immediately using standardized forms. In TE, infants under one year age (47%) including neonates (26%)...
To determine the role of nutritional parameters in influencing risk mortality institutionalized elderly.A prospective cohort study which subjects had several measured at baseline and were followed for 19 months. Time to death recorded starting immediately after enrollment.Fourteen long-term care facilities (LTCFs).Four hundred eight elderly residents aged 60 older who resided facility more than 6 weeks.At baseline, knee height, weight, mid-arm circumference (MAC), skin-fold thickness,...
In Brief Purpose: To evaluate the refractive outcome using 5 intraocular lens (IOL) calculation formulas to determine which best predicts refraction after pediatric cataract surgery. Setting: The Hospital for Sick Children, Toronto, Ontario, Canada. Methods: This study comprised a review of charts 158 consecutive patients aged 2 17 years old who were operated on by 1 staff surgeons between May 1992 and April 2000. performed total 206 extractions with primary or secondary IOL implantation....
Abstract Objective To establish the minimal change on a pain visual analog scale (VAS) associated with in self‐reported quality of life pediatric rheumatology patients. Methods Subjects were cohort 533 patients Toronto. Pain and perceived measured at 2 consecutive visits to clinic. Results Among who rated second visit as “a little better” “much better,” mean score 10‐cm VAS was reduced by 0.82 1.45 cm, respectively. For those whose changed worse” worse,” scores increased 1.90 3.69 cm....
A survey was conducted in 2002 to determine the pattern of factor prophylaxis use boys <or=18 years age with haemophilia followed North American treatment centres. Responses were obtained from 4553 cases (74% A, 26% B). The frequency prophylaxis, defined as infusion greater than or equal once per week for >or=45 weeks year, significantly higher vs. B (51% 32%, P< 0.0001), and severe living Canada USA (77% 47%, 0.0001). Use full-dose 25-40 IU kg(-1) VIII on alternate days (minimum three times...
The purpose of this study is to establish provincial diagnostic reference levels (DRLs) and determine whether process may help reduce the patient radiation dose from most frequently performed CT examinations.We investigated following examinations: head, chest, low-dose abdomen pelvis, abdomen, pelvis examinations. sample for each protocol included 15 patients average body weight (mean [± SD], 70 ± 20 kg). differences in between scanners were evaluated using one-way ANOVA. Correlations dose,...