A5075317213- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Cancer Treatment and Pharmacology
- Advanced Breast Cancer Therapies
- Global Cancer Incidence and Screening
- Neuroendocrine Tumor Research Advances
- BRCA gene mutations in cancer
- Economic and Financial Impacts of Cancer
- Estrogen and related hormone effects
- Neutropenia and Cancer Infections
- Breast Lesions and Carcinomas
- Health Systems, Economic Evaluations, Quality of Life
- Monoclonal and Polyclonal Antibodies Research
- Palliative Care and End-of-Life Issues
- Chemotherapy-induced cardiotoxicity and mitigation
- Lung Cancer Research Studies
- Peptidase Inhibition and Analysis
- Colorectal Cancer Treatments and Studies
- Neuroblastoma Research and Treatments
- Cancer and Skin Lesions
- Colorectal Cancer Screening and Detection
- Pancreatic and Hepatic Oncology Research
- Cancer Risks and Factors
- Ovarian cancer diagnosis and treatment
- Gastric Cancer Management and Outcomes
Dalhousie University
2015-2024
Breast Cancer Research Foundation
2024
Cancer Clinic
2024
Nova Scotia Health Authority
2017-2023
Queen Elizabeth II Health Sciences Centre
2014-2023
Health Sciences Centre
2007-2023
Roche (Switzerland)
2021
Nova Scotia Cancer Centre
2014-2020
Ontario Institute for Cancer Research
2011-2016
University of Toronto
2011-2016
An Institute of Medicine report recommends that patients with cancer receive a survivorship care plan (SCP). The trial objective was to determine if an SCP for breast survivors improves patient-reported outcomes.Women early-stage who completed primary treatment at least 3 months previously were eligible. Consenting allocated within two strata: less than 24 and ≥ since diagnosis. All transferred their own physician (PCP) follow-up. In addition discharge visit, the intervention group received...
The epidermal growth factor receptor (EGFR) is often overexpressed or dysregulated in a variety of solid tumours, including gastrointestinal (GI) malignancies. Agents targeting the EGFR-mediated signalling pathway are increasingly part therapeutic armamentarium for treatment advanced lung, head-and-neck, and colorectal carcinoma. EGFR inhibitors (EGFRIS) approved Canada include tyrosine kinase erlotinib gefitinib (in selected cases), monoclonal antibodies (mAbs) panitumumab cetuximab....
In contrast to female breast carcinoma, information regarding the prevalence and prognostic of new molecular markers is limited in male carcinoma. The objective this study was assess degree expression value estrogen receptors (ER), progesterone (PR), androgen (AR), bcl-2, p53, HER-2/neu, cyclin D1, MIB-1 a cohort carcinoma patients.A computerized search medical index, tumor registry, tissue registry used identify 111 patients with diagnosis primary adenocarcinoma seen between 1950-1992 at...
The isolation and analysis of circulating tumor cells (CTC) has the potential to provide minimally invasive diagnostic, prognostic predictive information. Widespread clinical implementation CTC been hampered by a lack comparative investigation between different analytic methodologies in clinically relevant settings. objective this study was evaluate four techniques–those that rely on surface antigen expression (EpCAM or CD45 using DynaBeads® EasySep™ systems) biophysical properties...
Carcinoid tumours are relatively rare and, in general, slow growing. They can be “non-functioning” tumours, presenting as a tumour mass, or “functioning” secondary to the production of several biopeptides leading carcinoid syndrome. Though these represent 0.25% an oncology practice, proper understanding clinical course disease and importance appropriate diagnostic therapeutic measures is very important. Proper patient management lead cure, particularly if fully resected, long-term palliation...
Aims The updated 2013 American Society of Clinical Oncology/College Pathologists ( ASCO / CAP ) human epidermal growth factor receptor 2 HER 2) testing guidelines include changes to in‐situ hybridization ISH interpretation criteria. We conducted a retrospective review consecutive cohort primary breast carcinomas assess the impact on classification and laboratory resource utilization, characterize pathobiology equivocal tumours. Methods results A total 904 dual‐probe 2/chromosome enumeration...
Case reports and small case series have described patients with sarcoidosis testicular carcinoma. The goals of this study were to determine the incidence in carcinoma seen at Mayo Clinic between 1950 1996 examine relation these two diseases, particularly regard therapy follow-up carcinoma.A computerized search patient data base was conducted identify all who had a diagnosis malignant tumor sarcoidosis.A total 14 identified. median age 31.5 years. Eleven presented Stage I disease 3 II...