Matti Aapro

ORCID: 0000-0003-3570-8319
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About
Contact & Profiles
Research Areas
  • Nausea and vomiting management
  • Cancer Treatment and Pharmacology
  • Anesthesia and Pain Management
  • Neutropenia and Cancer Infections
  • Breast Cancer Treatment Studies
  • Erythropoietin and Anemia Treatment
  • Pathogenesis and Treatment of Hiccups
  • Frailty in Older Adults
  • Iron Metabolism and Disorders
  • Advances in Oncology and Radiotherapy
  • Bone health and treatments
  • Biosimilars and Bioanalytical Methods
  • Colorectal Cancer Treatments and Studies
  • Health Systems, Economic Evaluations, Quality of Life
  • Cancer survivorship and care
  • Advanced Breast Cancer Therapies
  • Chemotherapy-related skin toxicity
  • Blood disorders and treatments
  • HER2/EGFR in Cancer Research
  • Palliative Care and End-of-Life Issues
  • Economic and Financial Impacts of Cancer
  • Chemotherapy-induced organ toxicity mitigation
  • Pharmacological Effects and Toxicity Studies
  • Lung Cancer Treatments and Mutations
  • Nutrition and Health in Aging

Clinique de Genolier
2016-2025

Breast Center
2015-2024

European CanCer Organisation
2019-2023

European School of Oncology
2000-2021

Hudson Institute
2018

John Wiley & Sons (United States)
2018

Ospedale A. Perrino
2018

Hospital Arnau de Vilanova
2018

Hospital Universitario Virgen del Rocío
2018

Lublin Oncology Center
2018

Advanced Breast Cancer (ABC) comprises both locally advanced breast cancer (LABC) and metastatic (MBC) [1.Cardoso F. Costa A. Norton L. ESO-ESMO 2nd International Consensus Guidelines for (ABC2). Simultaneous publication in.Breast. 2014; 23: 489-502Abstract Full Text PDF PubMed Scopus (252) Google Scholar]. Although treatable, MBC remains virtually an incurable disease with a median overall survival (OS) of ∼3 years 5-year only ∼25% [2.Cardoso Spence D. Mertz S. et al.Global analysis...

10.1093/annonc/mdy192 article EN publisher-specific-oa Annals of Oncology 2018-05-24

PURPOSE: To appraise the performance of Comprehensive Geriatric Assessment (CGA) in elderly cancer patients (≥ 65 years) and to evaluate whether it could add further information with respect Eastern Cooperative Oncology Group status (PS). PATIENTS AND METHODS: We studied 363 (195 males, 168 females; median age, 72 solid (n = 271) or hematologic 92) tumors. In addition PS, their physical function was assessed by means activity daily living (ADL) instrumental activities (IADL) scales....

10.1200/jco.20.2.494 article EN Journal of Clinical Oncology 2002-01-15

PURPOSE: To appraise the performance of Comprehensive Geriatric Assessment (CGA) in elderly cancer patients (≥ 65 years) and to evaluate whether it could add further information with respect Eastern Cooperative Oncology Group status (PS). PATIENTS AND METHODS: We studied 363 (195 males, 168 females; median age, 72 solid (n = 271) or hematologic 92) tumors. In addition PS, their physical function was assessed by means activity daily living (ADL) instrumental activities (IADL) scales....

10.1200/jco.2002.20.2.494 article EN Journal of Clinical Oncology 2002-01-15

PURPOSE: This phase III study compared docetaxel with mitomycin plus vinblastine (MV) in patients metastatic breast cancer (MBC) progressing despite previous anthracycline-containing chemotherapy. PATIENTS AND METHODS: Patients (n = 392) were randomized to receive either 100 mg/m 2 intravenously (IV) every 3 weeks 203) or 12 IV 6 189), for a maximum of 10 3-week cycles. RESULTS: In an intention-to-treat analysis, produced significantly higher response rates than MV overall (30.0% v 11.6%; P...

10.1200/jco.1999.17.5.1413 article EN Journal of Clinical Oncology 1999-05-01

Advanced breast cancer (ABC) is a treatable but still generally incurable disease. The goals of care are to optimize both length and quality life. Due continuous research, several advances have been made, particularly for the human epidermal growth factor receptor 2 (HER-2)-positive luminal-like subtypes. Notwithstanding these advances, median overall survival patients with ABC only 2–3 years, although range wide [1–5], may be longer treated in specialized institutions [6].

10.1093/annonc/mdu385 article EN cc-by-nc-nd Annals of Oncology 2014-09-19

•The clinical course of advanced cancer for many patients with bone metastases can be transformed through optimum multidisciplinary management.•Bone-targeted agents significantly reduce skeletal morbidity in across tumour types and should part standard treatment.•Treatment-induced loss increases fracture risk may require use a bone-targeted agent addition to lifestyle modifications.•The bisphosphonate adjuvant therapies postmenopausal early breast reduces recurrence improves survival.

10.1016/j.annonc.2020.07.019 article EN publisher-specific-oa Annals of Oncology 2020-08-12
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