A5101714159- Nutrition and Health in Aging
- Thyroid Disorders and Treatments
- Liver Disease Diagnosis and Treatment
- Folate and B Vitamins Research
- Birth, Development, and Health
- Iron Metabolism and Disorders
- Pancreatitis Pathology and Treatment
- Advanced Glycation End Products research
- Metabolism, Diabetes, and Cancer
- Renin-Angiotensin System Studies
- Reproductive System and Pregnancy
- Ferroptosis and cancer prognosis
- Parathyroid Disorders and Treatments
- Bone health and osteoporosis research
- Pregnancy and preeclampsia studies
- Chronic Kidney Disease and Diabetes
- Cancer, Lipids, and Metabolism
- Glaucoma and retinal disorders
- Gestational Diabetes Research and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Ocular Surface and Contact Lens
- Pharmacological Effects of Natural Compounds
- Bone Metabolism and Diseases
- RNA modifications and cancer
- Prenatal Screening and Diagnostics
Institute of Microbiology
2003-2025
Chinese Academy of Sciences
2003-2025
Lanzhou University
2015-2025
First Hospital of Lanzhou University
2012-2025
Wake Forest University
2003-2025
Zhejiang Cancer Hospital
2024-2025
Microbiology Institute of Shaanxi
2003-2025
Jinan University
2025
First Affiliated Hospital of Henan University of Traditional Chinese Medicine
2025
Henan University of Traditional Chinese Medicine
2025
Abstract In recent years, an increasing number of circular RNAs (circRNAs) have been discovered in hepatocellular carcinoma (HCC). However, the functions most circRNAs require further investigation. Here, we found that circBACH1 was significantly upregulated HCC tissues and high levels were closely associated with poor prognosis. addition, could promote growth by accelerating cell cycle progression vitro vivo. We next investigated cellular molecular mechanisms inhibited p27 translation,...
To assess the effect of obesity or a high body mass index (BMI) on risk severe outcomes in patients with coronavirus disease 2019 (COVID-19).Studies relationship between BMI and COVID-19 since December 2019. The odds ratio (OR) weighted mean difference (WMD) their 95% confidence intervals (CIs) were used to size.BMI was significantly increased illness (WMD: 1.18; CI: 0.42-1.93), who admitted an intensive care unit (ICU) 1.46; 0.96-1.97), required invasive mechanical ventilation (IMV) 2.70,...
Background Four CGRP Monoclonal Antibodies (mAbs) have been approved for migraine prophylaxis by the Food and Drug Administration (FDA) since 2018. However, there are concerns about safety of these four drugs real-world use.
Background and objective Glycation is a common post-transcriptional modification of proteins. Previous studies have shown that advanced glycation end modified transferrin (AGE-Tf) levels in diabetic rat kidney tissues were increased; however, its role nephropathy remains unclear. In this study, differences degree Tf sites induced by differing high glucose concentrations vitro the effect on total iron binding capacity (TIBC) observed. Moreover, AGE-Tf human renal tubular epithelial cells...
Background Vitamin D is thought to play a role in the development of migraine, but nature relationship still not fully understood. Although some studies have shown an association between vitamin deficiency and other had inconsistent or inconclusive results. Therefore, further research needed better understand migraine headaches. Methods We selected 9142 participants from 2001–2004 National Health Nutrition Examination Survey (NHANES). In our study, term "serum D" refers concentration 25OHD2...
Age-related changes in adipose tissue impact chronic medical diseases and mobility disability but mechanism remains poorly understood. The goal of this study is to define methods for phenotyping unique characteristics from older adults. Older adults enrolled Study Muscle, Mobility Aging selected the ancillary (SOMMA-AT; N=210, 52.38% women, 76.12±4.37 years) were assessed regional adiposity by whole-body magnetic resonance (AMRA) underwent a needle-aspiration biopsy abdominal subcutaneous...
To investigate the association between impaired thyroid hormone sensitivity and diabetic nephropathy (DN) in euthyroid patients with type 2 diabetes mellitus (T2DM). 1305 T2DM who were hospitalized Endocrinology Department of First Hospital Lanzhou University July 2021 August 2023 selected. Several indices, such as parameters feedback quantile index (PTFQI), (TFQI), stimulating (TSHI), serum-free triiodothyronine to free thyroxine (FT3/FT4) ratio, thyrotropin resistance (TT4RI) evaluate...
Although intracranial pressure (ICP) monitoring of patients with severe traumatic brain injury (TBI) is recommended by the Brain Trauma Foundation, any benefits remain controversial.To evaluate effects ICP on mortality and functional outcomes in diffuse TBI.Data were collected TBI (Glasgow Coma Scale [GCS] score admission <9 Marshall Class II-IV) treated from January 2012 to December 2013 24 hospitals (17 level I trauma centers 7 II centers) 9 Chinese provinces. We evaluated impact 6-month...
The surface structures of archaeal cells, many which exist at high temperatures, salinity, and non-physiological pH, are key factors for their adaptation to extreme living conditions. In the haloarchaeon Haloarcula hispanica, we have discovered a thin filamentous appendage called tat-fimbriae ("tafi"), were identified be composed three protein subunits, TafA, TafC, TafE, among TafA is major fimbrial subunit. Molecular genetic evidence demonstrates was transported through twin-arginine...
The nucleocapsid (N) protein of the severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) is an important antigen for early diagnosis SARS and development vaccines. It was expressed in Escherichia coli as a fusion with human glutathione S-transferase (hGST) confirmed by Western blotting analysis. This recombinant N (hGST-N) purified used to measure SARS-CoV N-specific antibody sera eight patients enzyme-linked immunosorbent assay. Specific response this 100% positive...