Oral common blue nevus is an asymptomatic, benign, rare, pigmented lesion and sometimes clinically indistinguishable from other lesions such as the cellular or early-stage malignant melanoma. Since it shows clinical similarities with a that can itself suffer transformation, decisive diagnosis crucial for adequate treatment, follow-up, prognosis. Diagnosis confirmation given by histological analysis, reason why most oral are excised. The following case presents asymptomatic of hard palate...

Synovial haemangioma is a rare benign entity, most common in children and adolescents. These tumours can extensively infiltrate joint structures periarticular soft tissues, making management challenging. Magnetic resonance imaging (MRI) has key role diagnosis therapeutic planning. The authors report the case of 17‑year‑old male with multiple synovial haemangiomas, highlighting complexity essential MRI assessment treatment.

Introduction Hepatocellular carcinoma (HCC) holds high cancer mortality worldwide. Immunotherapy-based combination therapy, currently the first-line (1L) standard of care in advanced HCC, has shifted treatment paradigm concerning both efficacy and safety outcomes. Data on immune-related adverse events surrogacy for outcomes is mixed. Case Report We report case a 58-year-old male with chronic Hepatitis C virus infection who presented voluminous shoulder HCC metastasis. Albeit an initial...

Introduction: The Urgeiriça mines were once the main uranium producer in Portugal. aim of this study was to estimate benefit low-dose chest computed tomography (LDCT) for lung cancer screening former miners that considered as being at high-risk.Methods: A subgroup Uranium National Company exposed and with a smoking load greater than 20 pack-years, agreed perform LDCT. Fleischner Society Guidelines used classify nodules establish follow-up.Results: Initially, 265 employees included. mean time...

Hereditary hemorrhagic telangiectasia is a rare multi-systemic autosomal dominant disorder characterized by dysplasia of the vascular connective tissue and recurrent bleeding tendency. Epistaxis most common earliest symptom. It usually mild to moderate, however, in some patients it can be severe with significant interference quality life. We report case patient hereditary telangiectasia, which an episode refractory epistaxis was treated radiofrequency fibrin sealant. Control acute...

Abstract A previously healthy 15-year-old teenage boy was admitted for fever and heart failure. Myocarditis suspected, endomyocardial biopsy revealed giant cell myocarditis. Immunosuppressive treatment initiated, with excellent response. plausible link to previous leptospirosis identified. At 18-month follow-up, left ventricular function is normal. Only one other reported case of paediatric myocarditis had such a favourable outcome.

Introduction: Since the first autograft ossiculoplasty in 1957 with Hall and Rytzner, ossicules remanents became an option tympanoplasties ossicular reconstruction due to its biocompatibility, easy availability low cost. However, use patients chronic otitis media cholesteatoma declined by possibility of harboring residual cholesteatoma. The authors investigate if removed during surgery have histopathological findings that may lead recurrence or functional compromise timpanoplasty.  Material...

Introduction: Mucosal melanoma of the head and neck is an uncommon disease with poor prognosis. Material Methods: Retrospective chart review 32 patients treated for mucosal in a cancer center from 1998 to 2012. Results: There were cases average age 70. The primary tumor was located nasal cavity 24 oral 8 patients. majority (23) underwent surgical treatment. Of these, 16 proposed adjunctive therapy radiotherapy. Follow-up time ranged between 26 days 10 years. five year survival rate 18%....

Objectivos: Revisao da casuistica de fistulas liquido cefalorraquidiano (LCR) nasosinusais e avaliacao experiencia tratamento endonasal endoscopico destes defeitos base do crânio.Metodos: Foram recolhidas forma retrospectiva informacoes dos doentes referenciados a consulta urgencia departamento Otorrinolaringologia Hospital Egas Moniz - Centro Hospitalar Lisboa Ocidental, com sintomas e/ou sinais fistula LCR nasosinusais; intervencionados diagnostico LCR; submetidos outros procedimentos...

Introduction: Since its introduction in the 1980s, functional endoscopic sinus surgery (FESS) met a great development and expansion to other surgical areas. Nevertheless, modern technique did not overcome risks dangerousness of FESS, complications are still number one reason for malpractice claims otorhinolaryngology head neck US. The objective this work is present practical attitudes prevent treat FESS complications, based on clinical experience, cadaveric training literature revision....

Objective 1) Describe the first reported case of paranasal sinus actinomycosis associated with an orbital complication. 2) other unusual features case: occurrence infection in immunocompetent pregnant patient, involvement ethmoid sinus, safety a surgical treatment 15‐week patient. Method Case report 25‐year‐old woman, 15 weeks pregnant. Disease studied: Ethmoid complicated by subperiosteal abscess. Setting: Tertiary referral university hospital. Intervention: Intravenous antibiotic therapy...

Early Glottic Carcinomas can have different treatments according to the surgeon, institution or country where they are treated. Radiotherapy, parcial laringectomies and Transoral LASER surgery, therapeutic options accepted with similar results in treatment of early glottic tumors. In last years Surgery has demonstrated be an option some advantages comparatively other options: good local control, low morbidity, function preservation, cost.We retrospective availed patients otorhinolaringology...

Small-cell bladder cancer (SCBC) is a rare subtype of with aggressive behavior and poor prognosis. Here, we report the case 50-year-old man who presented hematuria for one month. A computed tomography scan showed an exophytic lesion on right posterolateral wall single liver metastasis 14 mm diameter. Transurethral resection tumor was performed, postoperative examination specimen muscle-invasive SCBC. Initially, patient treated neoadjuvant chemotherapy. Rapid clinical imaging deterioration...

Objective: Assessment of the surgical benefit in children a canal wall up mastoidectomy with Tos Type 1 tympanoplasty over alone patients chronic suppurative otitis media (CSupOM) tympanic membrane (TM) perforation. Study Design: Retrospective study. Setting: Tertiary care hospital. Methods: A retrospective chart review CSupOM younger than 18-years old and admitted for elective between 2010 2013 was conducted. Primary cases submitted to (according classification 1993) were selected divided...

Abstract Background Anastomotic leakage (AL) after colorectal resections is a common surgical experience and the most frequent major adverse outcome. Early recognition of AL critical to reduce mortality. We aim evaluate incidence, diagnostic criteria, morbidity, mortality related with AL. Methods This cohort, descriptive retrospective, single-centred study consecutive patients who underwent surgery anastomosis due cancer, over 4-year period (2013–2016). Results From 2013 2016, total 480 were...

Acute liver failure (ALF) due to diffuse infiltrating solid malignancy without any focal lesions on radiographic imaging is rare.A 70-year-old man was admitted mental confusion, abdominal pain, and ALF. Three years before, he had undergone a left nephrectomy for urothelial carcinoma followed by adjuvant chemotherapy. The computed tomography (CT) showed hepatomegaly ascites. Ascitic fluid transudate characteristics, with no malignant cells. Percutaneous biopsy (LB) infiltration of metastatic...

O tumor fibroso solitário (TFS) é um benigno raro de células fusiformes natureza mesenquimatosa que geralmente ocorre na pleura, mas pode existir noutras localizações, nomeadamente região da cabeça e pescoço, podendo envolver a órbita, cavidade oral os seios perinasais. Na literatura apenas existem três casos reportados TFS do canal auditivo externo. Descreve-se o quarto caso realiza-se uma revisão literatura. Uma doente 27 anos apresentou-se com neoformação parede posterior externo,...

You have accessJournal of UrologyProstate Cancer: Basic Research & Pathophysiology I (MP33)1 Sep 2021MP33-02 UNRAVELING GENOMIC ALTERATIONS OF CRIBRIFORM AND INTRADUCTAL PROSTATE CANCER Rui Bernardino, Henrique, Herminia Pereira, Luis Severo, Rune Matthiesen, João Pimentel, and Campos Pinheiro BernardinoRui Bernardino More articles by this author , HenriqueRui Henrique PereiraHerminia Pereira SeveroLuis Severo MatthiesenRune Matthiesen PimentelJoão Pimentel PinheiroLuis View All Author...