A5101236620- Parathyroid Disorders and Treatments
- Breast Cancer Treatment Studies
- Ion Transport and Channel Regulation
- Bone health and treatments
- ATP Synthase and ATPases Research
- Inflammatory Bowel Disease
- Birth, Development, and Health
- Sexual Differentiation and Disorders
- Autoimmune and Inflammatory Disorders
- Medical Imaging and Pathology Studies
- Global Cancer Incidence and Screening
- Knee injuries and reconstruction techniques
- HER2/EGFR in Cancer Research
- Electrolyte and hormonal disorders
- Cancer Treatment and Pharmacology
- Breast Implant and Reconstruction
- Osteoarthritis Treatment and Mechanisms
- Lower Extremity Biomechanics and Pathologies
- Genetic Syndromes and Imprinting
- Cancer, Hypoxia, and Metabolism
- Diagnosis and treatment of tuberculosis
Kunming Medical University
2023
MRC Human Immunology Unit
2023
MRC Weatherall Institute of Molecular Medicine
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2022
Peking Union Medical College Hospital
2018-2022
Acidic environments reduce the intracellular pH (pHi) of most cells to levels that are sub-optimal for growth and cellular functions. Yet, cancers maintain an alkaline cytoplasm despite low extracellular (pHe). Raised pHi is thought be beneficial tumor progression invasiveness. However, transport mechanisms underpinning this adaptation have not been studied systematically. Here, we characterize pHe-pHi relationship in 66 colorectal cancer cell lines identify acid-loading anion exchanger 2...
The rate of breast-conserving surgery (BCS) is low in China. Many patients choose mastectomy even when informed that there no difference the overall survival compared with BCS plus radiotherapy. This study aimed to investigate factors influenced surgical choice eligible for BCS.Female breast carcinoma were enrolled a single center from March 2016 January 2017. They made their own decision regarding approach. Univariate analysis was employed determine associated different approaches....
Aim: Compare the two-weekly regimens of nanoparticle albumin-bound paclitaxel (nab-P) with solvent-based (sb-P) as neoadjuvant chemotherapy for breast cancer. Materials & methods: Patients (n = 162) operable early cancer received four cycles dose-dense epirubicin and cyclophosphamide followed by nab-P 83) or sb-P 79), trastuzumab when needed. Results: Across all patients, ypT0 ypN0 ypT0/is pathological complete response rates in group were not superior to those group. However,...
Abstract Objective :Previous studies have confirmed that Ascorbic Acid(AA) can promote cartilage repair and improve differentiation of bone marrow mesenchymal stem cells. However, the use microfractures(MFX) combined with AA in damage has not been studied. The aim this study is to explore beneficial effects combination MFX repair. Methods: Sixty New Zealand white rabbits were randomly divided into 5 groups (12 knees each): group 4 different concentrations treatment (1mg/ml, 3mg/ml, 10mg/ml,...