A multiresidue method for the simultaneous and rapid analysis of 360 pesticides in representative agricultural produce (brown rice, orange, spinach, potato) was developed using a modified QuEChERS procedure combined with gas chromatography–tandem mass spectrometry (GC-MS/MS). Selected reaction monitoring transition parameters (e.g., collision energy, precursor product ions) MS/MS were optimized to achieve best selectivity sensitivity wide range GC-amenable pesticides. short (20 m) microbore...

A screening method for simultaneous analysis of 379 pesticides in human serum was developed using liquid chromatography–tandem mass spectrometry (LC–MS/MS). Electrospray ionization with positive/negative switching mode LC–MS/MS adopted, and scheduled multiple reaction monitoring each target compound established. The limit quantitation 10 ng/mL 94.5% the total pesticides, correlation coefficients calibration were ≥0.990 93.9% pesticides. For sample preparation, scaled-down QuEChERS used....

Multiresidual pesticide analysis in hair can provide useful perspectives on the relationship between pesticides and human health. To establish a rapid simultaneous analytical method using LC-MS/MS GC-MS/MS, optimization of pulverization, extraction solvent purification with dispersive SPE was performed for 300 pesticides. Hair pulverization standardized ball mill, at 30 Hz 20 min (10 twice), 3-mm diameter beads. For extraction, 0.1% formic acid acetonitrile selected, PSA d-SPE chosen...

The present study systemically investigated the influence of crop oil concentrate (COC) on pesticide behavior apples. Surface-enhanced Raman scattering was employed to monitor persistence and penetration carbaryl (a systemic insecticide) thiram nonsystemic fungicide). results revealed that COC significantly enhanced depth by 38.7% increased relative intensity within plant tissue (Z = −120 μm) 81.3% after 1-day exposure. Liquid chromatography with tandem mass spectrometry confirmed...

Pesticide residues on fruits pose a global food safety concern, emphasizing the need for effective and practical removal strategies to ensure safe consumption. This study investigates efficacy of household ingredients (corn starch, all-purpose flour, rice flour baking soda) four commercial fresh produce wash products in eliminating model pesticide thiabendazole with without non-ionic surfactant Alligare 90® from postharvest fruits. Surface-enhanced Raman spectroscopy (SERS) was employed...

Developmental perfluorooctanesulfonic acid (PFOS) exposure in zebrafish reduces digestive gene expression and pancreas length, indicating exocrine insufficiency. This project focuses on the production function of proteases with PFOS exposure. We test hypothesis that developmental impairs absence severe morphological changes. Three larval timepoints were assessed, where nutrient source varies (yolk feed at 4 days post fertilization (dpf), yolk depleted 6 dpf exogenously fed 9 dpf) to...

Multiresidual pesticide determination in a biological sample is essential for an immediate decision and response related to various intoxications. A rapid simultaneous analytical method 260 pesticides human urine was developed validated using liquid chromatography-tandem mass spectrometry (LC-MS/MS). High speed positive/negative switching electrospray ionization (ESI) mode used, scheduled multiple reaction monitoring (MRM) optimized. Three versions of scaled-down QuEChERS procedures were...

Background and Aims: Cannabigerol (CBG) is a nonintoxicating cannabinoid synthesized in the Cannabis sativa plant that incorporated into dietary supplements. This study investigated influence of fat an emulsified delivery vehicle on CBG pharmacokinetics (PKs) after oral ingestion by adults.

Dermal & inhalation exposure was examined and according to these results, risk assessment of agricultural workers thiamethoxam performed during pesticide mixing/loading hand-held sprayer application (11 replicates, each about 1000 L spray suspension) in vineyards. For the whole body dosimetry (WBD), clothing (Outer inner), gauze, nitrile gloves were analyzed determine dermal using whole-body protocol. The measured a glass fiber filter with an IOM sampler. Analytical method validation...

Background and Objectives The purpose of the present study was to provide hearing threshold levels in elderly Korean population, compare data with that International Organization for Standardization (ISO) 7029 (2000). Subjects Methods Data were collected from a total 526 ears 112 males 151 females aged 60-84 years. All participants screened otologically by procedure given ISO 8253-1 (2010). Results showed pure-tone average gradually elevated increasing age. amount loss greater than females,...

The dissipation patterns of cyantraniliprole and its metabolite IN-J9Z38 were investigated using proso millet (Panicum miliaceum) under open-field conditions to establish a pre-harvest interval. A simple sensitive analytical method was developed for analyzing residues ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) multiple reaction monitoring target compounds. validated in terms the instrumental limit quantitation, linearity, accuracy,...

Abstract A quantitative analysis of ginsenoside is very important for ginseng studies because each shows different medical activity and metabolic pathway. In this study, a rapid, simultaneous, 26 ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg2(R), Rg2(S), Rg3(S), Rg3(R), Rg5, Rg6, Rh1(R), Rh1(S), Rh2(R), Rh2(S), F1, F2, F3, F4, K, Mc, PPT(S), XVII, Y) in white, red Panax was established using multiple reaction monitoring (MRM) mode on ultra-high-performance liquid chromatography-tandem mass...

Abstract The dissipation of ethoprophos and tricyclazole in soil their translocation tendency to spinach were investigated. Prior field trials, the analytical method for determination these pesticide residues was optimized validated on spinach. trial conducted under greenhouse conditions two different pretreatment periods with pesticides. After treating pesticides 30 (PBI-30) 60 days (PBI-60) before seeding, samples collected study soil. Spinach harvested from soil, 50% 100% mature...

Exposure of agricultural workers in rice paddies to the insecticide chlorantraniliprole and its subsequent potential health risks were investigated during two scenarios (mixing/loading hand-held spraying). The exposure factors, such as outer dosimeter, inner gauze, nitrile gloves, calculated using whole-body dosimetry measure dermal exposure. inhalation was determined a fiberglass filter which is set with an Institute Occupational Medicine (IOM) sampler. A recovery test performed evaluate...

문장을 이용한 일반용 청능훈련 도구개발

어음을 이용한 청력검사기가 1920년 대 중반 처음으로 개발 된 이래 다양한 검사방법과 검사장비가 지속적으로 발전되어

Agricultural workers exposed to pesticides can experience adverse health impacts depending on toxicity and exposure amount. Whole-body dosimetry (WBD) is the most reliable, practical, realistic method for measuring exposure. Since validation of analytical experimental methodologies critical quantitative determination exposure, we conducted a procedure design an essential protocol WBD studies. Using fungicide kresoxim-methyl, matrix-matched standards were prepared with various matrices...

For more rapid and sensitive simultaneous analysis of a 356 pesticide multiresidues by gas chromatography–tandem mass spectrometry (GC–MS/MS), microbore (20 m length × 0.18 mm i.d.) column, instead the conventional narrow bore column (30 0.25 i.d.), pulsed pressure injection (PPI) were evaluated in this study. An time 35.2 min with was greatly reduced to 17.8 column. Retention times all target compounds on new adjusted using automated adjustment retention function. The gave significantly...

Abstract Endosulfan sulfate is a major oxidized metabolite of endosulfan, which broad-spectrum chlorinated cyclodiene insecticide. In this study, GC–MS-based metabolic profiles dead or live carp ( Cyprinus carpio ) exposed to endosulfan were investigated elucidate the molecular toxicological effects on carp. Three different extraction methods compared, and 50% methanol solution was chosen as an efficient method. Carp at concentration 8 ppb for 2 days. After exposure, whole body fish...

In this study, we proposed new self assessment of hearing loss in mobile phones and realized a function compensation for impaired person. The results experiments on phone showed that the test is sufficient to check based result can improve speech intelligibility persons.